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Search Results for " filovirus "

8

Compounds

Cat No. Product Name Synonyms Targets
T6377 Aloperine Apoptosis , Virus Protease , HIV Protease , Antibiotic , Autophagy
Aloperine exhibits anti-inflammatory, antibacterial, antiviral, and anti-tumor properties.
T3S1852 Cephaeline hydrochloride Others , Virus Protease , Influenza Virus
Cephaeline hydrochloride, a phenolic alkaloid found in Indian Ipecac, effectively inhibits the infection of viruses ZIKV and EBOV.
TN1480 Cephaeline Virus Protease , Influenza Virus , HIF
Cephaeline was highly active against protected primary CLL cells (relative IC50's 35nM ) and acted by repressing HIF-1α± and disturbing intracellular redox homeostasis.
T1583 Vorinostat MK0683,suberoylanilide hydroxamic acid,SAHA Apoptosis , Mitophagy , Virus Protease , HDAC , Autophagy
Vorinostat (SAHA) is a pan-histone deacetylase (HDAC) inhibitor (IC50=10 nM) with inhibitory activity against HDAC1/2/3/6/7/11. Vorinostat has antitumor activity, induces cell differentiation, blocks the cell cycle and i...
T8903 Retro-2 Retro 2,2-{[(5-methyl-2-thienyl)methylene]amino} Others , Virus Protease , Parasite , Autophagy
Retro-2 (2-{[(5-methyl-2-thienyl)methylene]amino}) is a plant toxin ricin inhibitor, itprotects HeLa cells against Ricin, Stx1 and Stx2, selectively blocks retrograde toxin trafficking at the early endosome-TGN (trans-Go...
T16914 SP187 UV4,MON-​DNJ Others , Virus Protease , Influenza Virus
SP187 (MON-DNJ) is a host-targeted iminosugar. It has anti-filovirus infection activity.SP187 is used for therapeutic use against influenza and dengue viruses.
T77078 Maftivimab
Maftivimab (REGN3470-3471-3479), also known as Atoltivimab, Odesivimab (Inmazeb), is a Filovirus inhibitor and a Food and Drug Administration (FDA)-approved agent for the research of Zaire ebolavirus infection [1].
T73652 Eritoran
Eritoran, a Toll-like receptor 4 (TLR4) antagonist, effectively protects mice from lethal infections caused by viruses such as the Ebola virus (EBOV) and Marburg virus (MARV). By decreasing granulocytosis levels, Eritora...
TargetMol