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Retro-2

Catalog No. T8903   CAS 1201652-50-7
Synonyms: Retro 2, 2-{[(5-methyl-2-thienyl)methylene]amino}

Retro-2 (2-{[(5-methyl-2-thienyl)methylene]amino}) is a plant toxin ricin inhibitor, itprotects HeLa cells against Ricin, Stx1 and Stx2, selectively blocks retrograde toxin trafficking at the early endosome-TGN (trans-Golgi network) interface.

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Retro-2 Chemical Structure
Retro-2, CAS 1201652-50-7
Pack Size Availability Price/USD Quantity
1 mg In stock $ 64.00
5 mg In stock $ 139.00
10 mg In stock $ 213.00
25 mg In stock $ 428.00
50 mg In stock $ 639.00
100 mg In stock $ 890.00
1 mL * 10 mM (in DMSO) In stock $ 159.00
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Purity: 96.08%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Retro-2 (2-{[(5-methyl-2-thienyl)methylene]amino}) is a plant toxin ricin inhibitor, itprotects HeLa cells against Ricin, Stx1 and Stx2, selectively blocks retrograde toxin trafficking at the early endosome-TGN (trans-Golgi network) interface.
Targets&IC50 Ebolavirus:12.2 µM (EC50)
Synonyms Retro 2, 2-{[(5-methyl-2-thienyl)methylene]amino}
Molecular Weight 320.41
Formula C19H16N2OS
CAS No. 1201652-50-7

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 20 mg/mL (62.42 mM)

TargetMolReferences and Literature

1. Morgens D W , Chan C , Kane A J , et al. Retro-2 protects cells from ricin toxicity by inhibiting ASNA1-mediated ER targeting and insertion of tail-anchored proteins[J]. eLife Sciences, 2019, 8.

Related compound libraries

This product is contained In the following compound libraries:
Anti-Parasitic Compound Library Autophagy Compound Library NO PAINS Compound Library Anti-Viral Compound Library Bioactive Compounds Library Max Anti-Infection Compound Library Inhibitor Library Bioactive Compound Library

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Keywords

Retro-2 1201652-50-7 Autophagy Microbiology/Virology Others Virus Protease Parasite LC3-II inhibit Inhibitor retrograde Shiga-like Golgi Filovirus toxins Retro 2 Retro2 GFP-LC3 trafficking 2-{[(5-methyl-2-thienyl)methylene]amino} inhibitor

 

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