epi — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T6829	EPI-001	EPI001,EPI 001	Apoptosis , Androgen Receptor , PPAR
	EPI-001 is an androgen receptor N-terminal domain antagonist with IC50 of ～6 μM and a selective PPAR-gamma modulator.		Apoptosis , Androgen Receptor , PPAR
T3S2372	7-epi-Taxol	7-Epitaxol,7-epi-Paclitaxel	Others , Microtubule Associated
	1. 7-epi-Taxol (7-Epitaxol) is the major derivative of taxol found in cells and that its presence does not alter, in a major way, the overall biological activity of taxol.		Others , Microtubule Associated
T13681	Epi-galantamine		AChE
	Epi-galantamine, a diastereomer of galantamine, is an alkaloid extracted from the bulbs and flowers of the Caucasian snowdrop (Galanthus woronowii). It acts as an AChE inhibitor, featuring an EC50 of 45.7 μM.		AChE
T5738	7-Epi 10-desacetyl paclitaxel	10-Deacetyl-7-epipaclitaxel,7-Epi-10-deacetyltaxol	Others
	7-Epi 10-desacetyl paclitaxel (10-Deacetyl-7-epipaclitaxel) shows IC50 values of 0.085 nM, against HeLa cells.		Others
TN2755	2-Desoxy-4-epi-pulchellin		Anti-infection
	2-Desoxy-4-epi-pulchellin has potent in vitro cytotoxicities against the K562, MCF-7, Hela, DU145, U937, H1975, SGC-7901, A549, MOLT-4, and HL60 cell lines with IC50 values ranging from 0.10 to 46.7uM, while it shows sig...		Anti-infection
TN7549	2-epi-Abamectin	epi-Avermectin B1a	Others
	2-epi-Abamectin, a degradation product of abamectin, exhibits toxicity towards the two-spotted spider mite in contact assays, possessing an LC50 value of 4 ppm. This indicates it is approximately 100-fold less potent tha...		Others
T28502	Ralaniten	EPI-002	Androgen Receptor
	Ralaniten (EPI-002) is a potent, specific, and orally active antagonist of the androgen receptor N-terminal structural domain (AR-NTD).Ralaniten inhibits AR transcriptional activity with an IC50 value of 7.4 μM.Ralanites...		Androgen Receptor
T37970	12-epi Leukotriene B4	12-epi Leukotriene B4	Others
	Leukotriene B4 (LTB4) compounds are produced by both enzymatic and non-enzymatic processes. The products of enzymatic origin, via Leukotriene A4 (LTA4) hydrolase, are stereospecifically 12(R). Non-enzymatic hydrolysis pr...		Others
T84617	15-epi Prostaglandin A1	15-epi PGA1	Others
	15-epiProstaglandin A1 (15-epiPGA1) is an R-stereoisomer of PGA1, belonging to the A-series prostaglandins derived from gorgonian soft corals. PGA1 is known for its effects on renal vasodilation, promoting sodium excreti...		Others
T36919	1α-Hydroxy-3-epi-vitamin D3	1α-Hydroxy-3-epi-vitamin D3	Others
	1α-Hydroxy-3-epi-vitamin D3, a natural metabolite derived from 1alpha,25-dihydroxyvitamin D3, effectively suppresses parathyroid hormone (PTH) secretion[1].		Others
TQ0247	7-Epi-docetaxel	7-Epidocetaxel,4-epi-Docetaxel,7-Epitaxotere	Others
	7-Epi-10-oxo-docetaxel (7-Epitaxotere) is a impurity of docetaxel.		Others
T60507	Utreloxastat	EPI 857,PTC857	Lipoxygenase
	Utreloxastat (PTC857) is a novel 15-lipoxygenase inhibitor that can be used to study amyotrophic lateral sclerosis .		Lipoxygenase
T35500	3-epi-25-hydroxy Vitamin D3	3-epi-25-hydroxy Vitamin D3	Others
	3-epi-25-hydroxy Vitamin D3is the C-3 epimer of 25-hydroxy vitamin D3.1Dietary administration of 3-epi-25-hydroxy vitamin D3(0.5 and 1 IU/g) decreases levels of serum parathyroid hormone (PTH) in male, but not female, we...		Others
T40200	5-epi-Jinkoheremol		Others
	5-epi-Jinkoheremol exhibits more potent fungicidal activity than validamycin.		Others
T36375	Ralaniten triacetate	EPI-506	Androgen Receptor
	Ralaniten triacetate (EPI-506), a precursor of Ralaniten, is a first-of-its-kind, orally active androgen receptor N-terminal structural domain (AR-NTD) inhibitor with anticancer activity and can be used to study prostate...		Androgen Receptor
T11214	EPI-589		Others
	EPI-589, a quinone derivative and oxidoreductase enzyme inhibitor, is considered safe and well tolerated, showing promise for the treatment of amyotrophic lateral sclerosis (ALS).		Others
TN3962	epi-Eudesmol		Others
	epi-Eudesmol is a natural product from Laggera alata var. montana C. D. Adams.		Others
TN2368	8-Epiloganic acid	8-Epi-Loganic acid	Others
	8-Epiloganic acid has antibacterial and antiviral effects.		Others
T36595	4-epi-Chlortetracycline (hydrochloride)		Others
	Chlortetracycline is an analog of tetracycline , a broad spectrum antibiotic. In addition to its actions against microorganisms, chlortetracycline suppresses inflammation by inhibiting neutrophil action and other aspects...		Others
T37001	7-epi Maresin 1		Others
	7-epi Maresin 1 is the inactive 7(S) epimer of Maresin 1 , which contains a 7(R) hydroxyl group. It can be used as an experimental negative control.		Others