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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T0054 | Disulfiram | Tetraethylthiuram disulfide,NSC 190940,TETD | Dehydrogenase , Interleukin , Pyroptosis |
Disulfiram (TETD) is an inhibitor of the acetaldehyde dehydrogenase ALDH, inhibiting hALDH1 and hALDH2 (IC50=0.15/1.45 μM) with specificity. Disulfiram is acutely sensitized to alcohol and also inhibits GSDMD pore format... | |||
TN2252 | Syrosingopine | Dopamine Receptor | |
Syrosingopine has selective depleting effect on brain amines is potentiated by combined treatment with disulfiram or fusaric acid, a dopamine beta-hydroxylase inhibitor. | |||
T61214 | EWP 815 | Phosphatase , Hydroxylase | |
EWP 815 is a disulfiram analogue that functions as a powerful inhibitor of Ins(1,4) P 2 phosphatase, Ins(1,4,5) P 3 5-phosphatase, and dopamine β-hydroxylase activity [1] [2]. | |||
T4876 | 2-(1H-Indol-3-yl)ethan-1-ol | Tryptophol,3-(2-Hydroxyethyl)indole,Indole-3-ethanol | Others , Endogenous Metabolite |
2-(1H-Indol-3-yl)ethan-1-ol (3-(2-Hydroxyethyl)indole) is a metabolite formed in the liver after disulfiram treatment that induces sleep in humans. It is also a secondary product of alcoholic fermentation. | |||
T35543 | Methyl Diethyldithiocarbamate | ||
Methyl diethyldithiocarbamate is an active metabolite of the aldehyde dehydrogenase inhibitor disulfiram .1It is produced by methylation of the disulfiram metabolite diethyldithiocarbamate in mouse liver microsomes.2Meth... |