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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T16914 | SP187 | UV4,MON-DNJ | Others , Virus Protease , Influenza Virus |
SP187 (MON-DNJ) is a host-targeted iminosugar. It has anti-filovirus infection activity.SP187 is used for therapeutic use against influenza and dengue viruses. | |||
T70516 | ToP-DNJ | ||
ToP-DNJ is a selective inhibitor of endoplasmic reticulum α-Glucosidase II, exhibiting antiflaviviral activity. | |||
T12039 | Miglustat | N-Butyldeoxynojirimycin,OGT918,NB-DNJ | Others |
Miglustat (NB-DNJ) is an alkylated product of imino sugar deoxynojirimycin.It is an inhibitor of glucosylceramide synthase, primarily to treat Type I Gaucher disease (GD1). | |||
TQ0155 | Miglustat hydrochloride | NB-DNJ hydrochloride,N-Butyldeoxynojirimycin hydrochloride,OGT918 hydrochloride | Transferase |
Miglustat hydrochloride (N-Butyldeoxynojirimycin hydrochloride) is an inhibitor of glucosylceramide synthase and can be used for studies about Type I Gaucher disease. | |||
T21344 | 1-Deoxynojirimycin hydrochloride | Moranoline,AT2220,Duvoglustat hydrochloride,1-Deoxynojirimycin,DNJ,deoxynojirimycin | PI3K , Antibacterial , Antibiotic , Glucosidase |
1-Deoxynojirimycin hydrochloride (Moranoline) is a potent and selective inhibitor of alpha-glucosidase, most commonly found in mulberry leaves. Duvoglustat is used to suppress the elevation of postprandial hyperglycemia. | |||
TP1080 | N-Nonyldeoxynojirimycin | NN-DNJ,Nonyl-DNJ | |
N-Nonyldeoxynojirimycin (NN-DNJ) is an inhibitor of acid α-glucosidase and α-1,6-glucosidase (IC50s = 0.42 and 8.4 μM, respectively). | |||
T60422 | 5-C-heptyl-DNJ | ||
5-heptyl-DNJ is an effective GAA agonist with a Ki of 0.0047 μM. 5-C-heptyl-DNJ increases GAA activities through chaperrone effects [1]. | |||
T70514 | Ganciclovir monophosphonate | ||
Ganciclovir monophosphonate is a synthetic analog of 2'-deoxy-guanosine which is used to treat or prevent cytomegalovirus (CMV) infections. It inhibits the replication of human CMV with an IC50 value of 0.01 μM and is ef... | |||
T70952 | UR-MK299 | ||
UR-MK299 is a NPY Y1 receptor antagonist. | |||
T74901 | PBI-6DNJ | ||
PBI-6DNJ, an orally active and potent multivalent glycosidase inhibitor, demonstrates significant inhibition activity against α-glucosidase from mice, featuring a K i value of 0.14 μM. It also exhibits notable hypoglycem... | |||
TQ0298 | Fagomine | D-Fagomine | ROS , glycosidase |
Fagomine (D-Fagomine) is a mild glycosidase inhibitor, an analog of 1-deoxynojirimycin (DNJ) with hypoglycemic activity, and Fagomine reduces intracellular reactive oxygen species (ROS) production and malondialdehyde (MD... | |||
T70954 | SP-187 HCl | ||
SP-187, also known as N-9-DNJ and UV-4B, is an alpha-Glucosidase inhibitor potentially for the treatment of dengue fever and influenza infection. Proline-producing strains of Serratia marcescens were more osmotolerant t... |