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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T4380 | Ac-CoA Synthase Inhibitor1 | ACSS2 inhibitor | RSV , Fatty Acid Synthase |
Ac-CoA Synthase Inhibitor1 (ACSS2 inhibitor) is the most potent and specific inhibitor of acetate-dependent acetyl-CoA synthetase 2 (ACSS2). | |||
T36626 | Lys-CoA | ||
Selective p300 histone acetyltransferase (HAT) inhibitor (IC50 = 50-500 nM). Exhibits approximately 100-fold selectivity for p300 over PCAF (IC50 = 200 μM). Inhibits p300-dependent transcription. Active in vivo. Lau et a... | |||
T73829 | Malonyl CoA | ||
Malonyl CoA serves as a substrate in fatty acid biosynthesis while inhibiting fatty acid oxidation. It also acts as a reversible inhibitor of mitochondrial carnitine palmitoyltransferase (CPT) 1 [1] [2]. | |||
T74197 | Pimeloyl-CoA | ||
Pimeloyl-CoA, a precursor to biotin in Escherichia coli, serves as a key compound for researching the de novo biosynthesis pathway of biotin in this bacterium [1]. | |||
T82792 | Caffeoyl-CoA | ||
Caffeoyl-CoA can be isolated from the leaf tissues of Gramineae, exhibiting a Km value of 1.45 μM [1]. | |||
T74171 | Crotonyl-CoA | ||
Crotonyl-CoA, an intermediate in the fermentation of butyric acid as well as in the metabolism of lysine and tryptophan, plays a crucial role in the metabolism of fatty acids and amino acids [1]. | |||
T37958 | Acetyl Coenzyme A trisodium | Acetyl-CoA trisodium | OXPHOS , Endogenous Metabolite , Autophagy |
Acetyl Coenzyme A trisodium (Acetyl-CoA trisodium) is an important compound in glucose metabolism and lipid metabolism and is involved in the tricarboxylic acid cycle. | |||
T73951 | Lys-CoA TFA | ||
Lys-CoA TFA, a selective p300 histone acetyltransferase (HAT) inhibitor (IC 50 =50-500 nM), exhibits a specificity that exceeds 100-fold over PCAF (IC 50 =200 μM). This compound effectively suppresses transcriptional act... | |||
T79520 | HMG-CoA Reductase-IN-1 | ||
HMG-CoA Reductase-IN-1 is an inhibitor of HMG-CoA reductase, demonstrating strong inhibitory activity on HMGR and affinity for OATP1B1, with pIC50 and pKm values of 8.54 and 1.98, respectively. It is utilized in hypercho... | |||
T72180 | Acetyl-CoA Carboxylase-IN-1 | ||
Acetyl-CoA Carboxylase-IN-1 is a potent inhibitor of acetyl-CoA carboxylase (ACC), exhibiting an inhibition concentration (IC50) of less than 5 nM. This compound also displays antibacterial activity. | |||
T36827 | Acetoacetyl Coenzyme A (sodium salt hydrate) | Acetoacetyl-CoA | |
Acetoacetyl-coenzyme A (acetoacetyl-CoA) is a precursor to HMG-CoA in the isoprenoid pathway.[1],[2] It is reversibly converted to acetyl-CoA by acetoacetyl-CoA thiolase in the mitochondria. Acetoacetyl-CoA thiolase (T2)... | |||
T14342 | Atorvastatin lactone | HMG-CoA Reductase | |
Atorvastatin lactone is a prodrug form of atorvastatin. Which is an orally active 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor. | |||
T78511 | Oleoyl coenzyme A lithium | Oleoyl-CoA lithium | |
Oleoyl coenzyme A (Oleoyl-CoA) lithium, a thioester derived from oleic acid and coenzyme A, functions as a metabolite in both Escherichia coli and mice [1] [2]. | |||
T32598 | Lauroyl-coenzyme A | Dodecanoyl-coa,Coenzyme A, lauroyl-,Lauroyl-coa | |
Lauroyl-coenzyme A can function as an acyl group carrier, acetyl-CoA. It can be used as an intermediate in lipid metabolism and is involved in lipid biosynthesis and fatty acid transport. | |||
T37323 | Succinyl-Coenzyme A sodium salt | Succinyl-CoA sodium salt,Succinyl-Coenzyme A (sodium salt),Succinyl-CoA | Endogenous Metabolite |
Succinyl-Coenzyme A sodium salt(Succinyl-CoA sodium salt) participates in the citric acid cycle, where it is converted to succinic acid.Succinyl-Coenzyme A (sodium salt) is involved in a variety of metabolic reactions in... | |||
T9214 | ELOVL6-IN-1 | Others | |
ELOVL6-IN-1 is a potent, orally active and selective ELOVL6 inhibitor. ELOVL6-IN-1 dose-dependently inhibits mouse ELOVL6 activities, with an IC50 value of 0.350 μM. ELOVL6-IN-1 inhibits ELOVL6 in a noncompetitive manner... | |||
T3510 | Olumacostat Glasaretil | Acetyl-CoA Carboxylase | |
Olumacostat glasaretil is a small molecule inhibitor of acetyl coenzyme A carboxylase (ACC). It has been used in trials studying the treatment of Acne Vulgaris. | |||
T12490 | Pitavastatin lactone | Others | |
Pitavastatin lactone is a major Pitavastatin metabolite in humans. Pitavastatin is a potent competitive inhibitor of HMG-CoA reductase little metabolized in hepatic microsomes. | |||
T16068 | MF-438 | Dehydrogenase , Stearoyl-CoA Desaturase (SCD) | |
MF-438 is an effective and orally bioavailable stearoyl-CoA desaturase 1 (SCD1) inhibitor (EC50: 2.3 nM for rSCD1). | |||
T13356 | XEN723 | Dehydrogenase , Stearoyl-CoA Desaturase (SCD) | |
XEN723 is a potent thiazolylimidazolidinone Stearoyl-CoA Desaturase (SCD1) inhibitor(IC50s of 45 and 524 nM in mouse and HepG2 cell, respectively). |