cn2 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T82700	Cn2 toxin	β-Mammal toxin Cn2
	Cn2 toxin, a β-toxin, interacts with the voltage-sensing domain of voltage-gated sodium channels (NaV) [1].
T11373	GCN2-IN-1	A-92	Others
	GCN2-IN-1 (A-92) is an effective GCN2 inhibitor and can be used in research on the treatment of cancer as a chemotherapeutic agent.		Others
T11374	GCN2-IN-6		Others , PERK
	GCN2-IN-6 is also a eIF2α kinase PERK inhibitor with an IC50 of 0.26 nM (in enzymatic assay) and 230 nM (in cells). GCN2-IN-6 is a potent, and orally available GCN2 inhibitor confirmed by in-house enzymatic (IC50 of 1.8...		Others , PERK
T7494	TCN238	TCN 238	GluR
	TCN238 is an orally bioavailable positive allosteric modulator of the metabotropic glutamate receptor 4 (mGluR4with an EC50 of 1 μM).		GluR
T11375	GCN2iB		Others , Autophagy
	GCN2iB is an ATP-competitive inhibitor of a serine/threonine-protein kinase general control nonderepressible 2 (GCN2), with an IC50 of 2.4 nM.		Others , Autophagy
T63699	GCN2-IN-7
	GCN2-IN-7 is a selective, orally active general control nonderepressible 2 (GCN2) inhibitor with an IC50 value of 5 nM that exhibits antitumor effects in vivo.
T69829	GCN2iB acetate
	GCN2iB is a GCN2 inhibitor. GCN2iB may be useful for the treatment of cancer. The inhibition of GCN2 sensitizes cancer cells with low basal-level expression of asparagine synthetase (ASNS) to the antileukemic agent L-as...

Compounds

Cn2 toxin

T82700

Synonym: β-Mammal toxin Cn2

Target: Others, Autophagy

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPH-00361	Beta-mammal toxin Cn2 Protein, Centruroides noxius, Recombinant (His)	Centruroides noxius	P. pastoris (Yeast)
	Mammal beta-toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the activation voltage to more negative potentials. This toxin is active against mammals. Beta-mammal toxin Cn2 Protein, Centruro...
TMPY-01773	CNDP2 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	CNDP2 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 54.2 kDa and the accession number is CAC69883.1.
TMPH-01199	CNDP2 Protein, Human, Recombinant (E. coli, His)	Human	E. coli
	CNDP2 Protein, Human, Recombinant (E. coli, His) is expressed in E. coli.
TMPY-01739	CNDP2 Protein, Mouse, Recombinant (His)	Mouse	Baculovirus Insect Cells
	CNDP2 Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 54.22 kDa and the accession number is Q9D1A2.
TMPY-00988	Lipocalin-2/LCN2 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Lipocalin-2/LCN2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22.3 kDa and the accession number is P11672.
TMPY-00873	Lipocalin-2/LCN2 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Lipocalin-2/LCN2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22.7 kDa and the accession number is P80188-1.
TMPY-01003	TCN2 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	TCN2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46.7 kDa and the accession number is P20062-1.
TMPK-00672	CTGF/CCN2 Protein, Rhesus macaque, Recombinant (His)	Rhesus	HEK293 Cells
	Connective tissue growth factor (CTGF) is a member of the CCN matricellular protein family, consisting of four domains, that regulates the signaling of other growth factors and promotes kidney fibrosis.CTGF can simultane...
TMPJ-01162	CTGF/CCN2 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	CTGF/CCN2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 67-81 KDa and the accession number is Q5M8T4.
TMPJ-01163	CTGF/CCN2 Protein, Human, Recombinant (HEK293, His)	Human	HEK293 Cells
	Connective Tissue Growth Factor (CTGF), also known as CCN2, is a member of the CCN (CYR61/CTGF/NOV) family of secreted matricellular proteins. Like other CCN proteins, mature human CTGF consists of IGF-binding protein d...
TMPY-03697	SCN2B Protein, Human, Recombinant (His)	Human	HEK293 Cells
	SCN2B Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 34.7 kDa and the accession number is O60939.
TMPY-02192	TCN2 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	TCN2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 47 kDa and the accession number is O88968.
TMPY-05203	Lipocalin-2/LCN2 Protein, Mouse, Recombinant	Mouse	HEK293 Cells
	Lipocalin-2/LCN2 Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 20.9 kDa and the accession number is P11672.
TMPK-01000	CTGF/CCN2 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	Connective tissue growth factor (CTGF) is a member of the CCN matricellular protein family, consisting of four domains, that regulates the signaling of other growth factors and promotes kidney fibrosis.CTGF can simultane...
TMPH-01069	CTGF/CCN2 Protein, Human, Recombinant (His)	Human	E. coli
	Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types ...
TMPY-03183	SCN2B Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	SCN2B Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 42.2 kDa and the accession number is O60939.
TMPH-02568	CTGF/CCN2 Protein, Mouse, Recombinant (GST)	Mouse	E. coli
	Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types ...
TMPJ-01113	RCN2 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Reticulocalbin-2 (RCN2, also named as ERC-55), is a 55-kDa Ca2+-binding protein containing six EF-hands, which was identified to be localized in endoplasmic reticulum. RCN2 is belonging to Reticulocalbin (RCN) family, th...
TMPJ-01161	CTGF/CCN2 Protein, Human, Recombinant	Human	HEK293 Cells
	CTGF/CCN2 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 16-25 KDa and the accession number is Q5M8T4.
TMPY-02316	Lipocalin-2/LCN2 Protein, Rat, Recombinant (His)	Rat	Baculovirus Insect Cells
	Lipocalin-2/LCN2 Protein, Rat, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 21.9 kDa and the accession number is P30152.