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Search Results for " casr "

20

Compounds

Cat No. Product Name Synonyms Targets
T79023 CaSR antagonist-1 CaSR
CaSR Antagonist-1 is a potent inhibitor of the calcium-sensing receptor (CaSR) with an inhibitory concentration (IC50) of 50 nM, suitable for the investigation of diseases related to dysregulated bone or mineral homeosta...
T3802 Ligustroflavone Nuezhenoside Others , CaSR
Ligustroflavone (Nuezhenoside) has anti-inflammatory activity.
T12846 SB-423562 CaSR
SB-423562 is a calcium-sensing receptor (CaSR) antagonist and can be used in studies about osteoporosis.
T15261 Evocalcet KHK7580 CaSR
Evocalcet (KHK7580) has an activating effect on the calcium-sensing receptor (CaSR).
T8457 NPS2390 GluR
NPS2390 is a first generation quinoxaline derivative that acts as a noncompetitive antagonist of mGluR1 and mGluR5 (IC50 of 5.2 and 82 nM, respectively)
T8403 Cinacalcet AMG 073 CaSR
Cinacalcet (AMG 073) is an orally active, allosteric Ca receptor (CaR) agonist, treatment of cardiovascular disease .
T22795 Gadolinium chloride CaSR
Gadolinium chloride is a calcium-sensing receptor (CaSR) agonist
T1641 Strontium ranelate Distrontium renelate,S12911 Calcium Channel , CaSR
Strontium ranelate (S12911), a strontium (II) salt of the ranelic acid, is a medication for osteoporosis. Studies indicate it can also slow the course of osteoarthritis of the knee. The drug is unusual in that it both in...
TP1236 Etelcalcetide hydrochloride AMG 416 hydrochloride,KAI-4169 hydrochloride CaSR
Etelcalcetide hydrochloride (AMG 416 hydrochloride) is a synthetic peptide that acts as an allosteric modulator of the calcium-sensing receptor (CaSR), effectively lowering parathyroid hormone (PTH) levels in patients wi...
T2406 Cinacalcet hydrochloride AMG-073 HCl,Cinacalcet HCl,AMG-073 hydrochloride,Cinacalcet CaSR
Cinacalcet hydrochloride (AMG-073 hydrochloride) is a naphthalene derivative and CALCIMIMETIC AGENT that increases the sensitivity of PARATHYROID GLAND calcium-sensing receptors to serum calcium. This action reduces para...
T1730 NPS-2143 SB262470,NPS 2143,SB 262470A Calcium Channel , CaSR
NPS-2143 (SB 262470A) is a novel potent and selective antagonist of Ca(2+) receptor.
T4967 NPS-2143 hydrochloride NPS-2143 HCL CaSR
NPS-2143 hydrochloride (NPS-2143 HCL) is a selective potent calcium ion-sensing receptor antagonist.
T40363 Poly-D-lysine hydrobromide (MW 30000-70000) Poly-D-lysine HBr (MW 30000-70000) CaSR
Poly-D-lysine hydrobromide (MW 30000-70000)(Poly-D-lysine HBr) is an orally available peptide CaSR agonist that removes proteinase K-resistant PrP from prion-infected SN56 neuroblastoma cells.
T23401 Strontium chloride Others , CaSR
Strontium chloride is an agonist of Calcium sensing receptor (CaSR) and directly affects C-type nerve fibers.
T7716 TNCA Lycoperodine-1 Others
TNCA (Lycoperodine-1) is a high-affinity CaSR ligand (CaSRL) with co-agonist activity.
T34385 Ronacaleret HCl SB 751689,SB 751689A,SB-751689A,SB-751689,SB751689A,SB751689 CaSR
Ronacaleret HCl (SB-751689) is a small molecule CaSR antagonist for the treatment of endocrine and metabolic diseases, skin and musculoskeletal disorders.
T13918 Tecalcet Hydrochloride R-568 hydrochloride,R-568 (hydrochloride) CaSR
Tecalcet Hydrochloride (R-568 hydrochloride) is an allosteric and positive modulator of the calcium-sensing receptor(CaSR). Tecalcet Hydrochloride increases the sensitivity to the activation of extracellular Ca2+.
T29541 AC265347 AC-265347 CaSR
AC265347 is a potent calcium-sensitive receptor (CaSR) agonist and ago-PAM orthosteric modulator with antitumour activity that inhibits neuroblastoma tumour growth by inducing differentiation.AC265347 can be used to stud...
T10666 Calhex 231 hydrochloride CaSR
Calhex 231 hydrochloride is a CaSR inhibitor with the potential for diabetic cardiomyopathy treatment. It blocks Ca2+-induced accumulation of [3H]inositol phosphate (IC50: 0.39 μM in HEK293 cells).
T11493 GSK3004774 Others
GSK3004774 is a nonabsorbable agonist of CaSR (pEC50: 7.3, 6.6, and 6.5 for human, mouse, and rat CaSR). GSK3004774 shows an EC50 of 50 nM for human CaSR.
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