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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T9608 | KL201 | Others | |
KL201 a circadian clock modulator, is a isoform-selective cryptochrome 1 (CRY1) stabilizer. KL201 lengthens the period of circadian rhythms in cells and tissues[1]. | |||
T22891 | KL001 | KL 001,KL-001 | Others |
KL 001 is a Cryptochrome protein (CRY) stabilizer. KL001 prevented ubiquitin-dependent degradation of CRY, resulting in lengthening of the circadian period. KL001-mediated CRY stabilization inhibited glucagon-induced glu... | |||
T32401 | KL044 | KL 044,KL-044 | Others |
KL044 is a cryptochrome 1 (CRY1) activator that prolongs circadian rhythms and inhibits PER2 activity. KL044 inhibits melanogenesis by inhibiting the cAMP/PKA/CREB pathway. | |||
T74743 | M47 | ||
M47, a small molecule, selectively targets and destabilizes Cryptochrome 1 (CRY1), promoting its degradation within the nucleus. This compound not only initiates apoptosis in Ras-transformed P53-deficient mouse skin fibr... | |||
T38433 | KS15 | ||
KS15 is a chemical compound that acts as an inhibitor on the interactions between cryptochromes, specifically CRY1 and CRY2, and the CLOCK: BMAL1 heterodimer. This compound, with an EC50 value of 4.9 μM, hinders the feed... |
Cat No. | Product Name | Species | Expression System |
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TMPH-01159 | CRY1 Protein, Human, Recombinant (His & Myc) | Human | E. coli |
CRY1 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 73.8 kDa and the accession number is Q16526. | |||
TMPH-00180 | Cry1Ab Protein, Bacillus thuringiensis subsp., Recombinant (His & SUMO) | Bacillus thuringiensis subsp. kurstaki | E. coli |
Promotes colloidosmotic lysis by binding to the midgut epithelial cells of many lepidopteran larvae. Cry1Ab Protein, Bacillus thuringiensis subsp., Recombinant (His & SUMO) is expressed in E. coli expression system with ... | |||
TMPH-00184 | Cry1Fb Protein, Bacillus thuringiensis subsp., Recombinant (His) | Bacillus thuringiensis subsp. morrisoni | E. coli |
Promotes colloidosmotic lysis by binding to the midgut epithelial cells of insects. Cry1Fb Protein, Bacillus thuringiensis subsp., Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predict... | |||
TMPH-00181 | Cry1Ia Protein, Bacillus thuringiensis subsp., Recombinant (His & KSI) | Bacillus thuringiensis subsp. Kurstaki | E. coli |
Promotes colloidosmotic lysis by binding to the midgut epithelial cells of certain coleopteran and lepidopteran species. Active on Plutella xylostella and Bombyx mori. Cry1Ia Protein, Bacillus thuringiensis subsp., Recom... | |||
TMPH-00179 | Cry1Ab Protein, Bacillus thuringiensis subsp., Recombinant (His) | Bacillus thuringiensis subsp. kurstaki | P. pastoris (Yeast) |
Promotes colloidosmotic lysis by binding to the midgut epithelial cells of many lepidopteran larvae. Cry1Ab Protein, Bacillus thuringiensis subsp., Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted ... | |||
TMPH-00177 | Cry1Bb Protein, Bacillus thuringiensis, Recombinant (His & Myc) | Bacillus thuringiensis | E. coli |
Promotes colloidosmotic lysis by binding to the midgut epithelial cells of many lepidopteran larvae. Cry1Bb Protein, Bacillus thuringiensis, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis... | |||
TMPH-00183 | Cry1Ac Protein, Bacillus thuringiensis subsp., Recombinant (GST) | Bacillus thuringiensis subsp. kurstaki | E. coli |
Promotes colloidosmotic lysis by binding to the midgut epithelial cells of many lepidopteran larvae. Cry1Ac Protein, Bacillus thuringiensis subsp., Recombinant (GST) is expressed in E. coli expression system with N-GST t... |