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Search Results for " crip "

Targets

11

Compounds

10

Recombinant Proteins

1

Libraries

Cat No. Product Name Synonyms Targets
T12218 NFAT Transcription Factor Regulator-1 IL Receptor
NFAT Transcription Factor Regulator-1 is an synthesis inhibitor of IL-2 (IC50 of 182 nM).
T6980 Scriptaid GCK1026,Scriptide Apoptosis , Influenza Virus , HDAC , Autophagy
Scriptaid (GCK1026) is an inhibitor of HDAC, and has a greater effect on acetylated H4 than H3.
T5842 Bromocriptine mesylate CB-154 Dopamine Receptor , Autophagy
Bromocriptine mesylate (CB-154) is a potent dopamine receptor agonist that binds the D2 receptor with highest affinity (Ki = 2.5 nM)
T12715 Reverse transcriptase-IN-1 HIV Protease
Reverse transcriptase-IN-1 is a diarylbenzopyrimidine (DABP) analogue and a potent inhibitor of HIV-1 nonnucleoside reverse transcriptase with an IC50of 13.7 nM.
T72206 Reverse transcriptase-IN-4
Reverse transcriptase-IN-4 is a potent, selective non-nucleoside reverse transcriptase (NNRT) inhibitor, demonstrating an EC50 of 0.053 μM against wild-type HIV-1 and 0.26 μM for the E138K HIV-1 mutant.
T72203 Reverse transcriptase-IN-3
Reverse transcriptase-IN-3, a pyrimidine-5-carboxamide derivative, functions as an inhibitor of HIV-1, demonstrating potent activity against both wild-type and mutant strains of HIV-1.
T72658 cRIPGBM chloride
cRIPGBM chloride is an orally active, proapoptotic compound derived from glioblastoma multiforme (GBM) cancer stem cells (CSCs). It specifically targets receptor-interacting protein kinase 2 (RIPK2) to trigger caspase 1-...
T68440 Epicriptine
Epicriptine or beta-dihydroergocryptine is a dopamine agonist of the ergoline class. It constitutes one third of the mixture known as dihydroergocryptine, the other two thirds consisting of alpha-dihydroergocryptine. The...
TP2291 Signal transducer and activator of transcription 6 fragment Others
The signal transducer and activator of transcription 6 fragments is a peptide with the sequence H2N-Ser-Tyr-Trp-Ser-Asp-Arg-Leu-Ile-Ile-OH, MW= 1152.3.
T40459 Transcriptional Intermediary Factor 2 (TIF2) (740-753) Transcriptional Intermediary Factor 2 (TIF2) (740-753)
Transcriptional Intermediary Factor 2 (TIF2) (740-753) is a 14-amino acid peptide that serves as a coactivator of TIF-2 protein. It specifically covers residues 740-753 of the TIF-2 protein.
T19250 cRIPGBM TNF
cRIPGBM, a proapoptotic derivative of RIPGBM, selectively induces apoptosis in GBM cancer stem cells (CSCs) by targeting receptor-interacting protein kinase 2 (RIPK2), demonstrating an EC50 of 68 nM in GBM-1 cells [1].

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-03342 CRIP2 Protein, Human, Recombinant (His & GST) Human Baculovirus Insect Cells
CRIP2 Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 50.3 kDa and the accession number is P52943.
TMPY-03459 CRIP2 Protein, Human, Recombinant Human Baculovirus Insect Cells
CRIP2 Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 22.6 kDa and the accession number is P52943.
TMPY-01413 Cripto Protein, Human, Recombinant (His) Human HEK293 Cells
Cripto Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.4 kDa and the accession number is AAH22393.1.
TMPY-02679 Cripto Protein, Rat, Recombinant (hFc) Rat HEK293 Cells
Cripto Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 41 kDa and the accession number is XP_001056317.2.
TMPY-03908 Cripto Protein, Rat, Recombinant (His) Rat HEK293 Cells
Cripto Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.5 kDa and the accession number is XP_001056317.2.
TMPY-03750 CRIPT Protein, Human, Recombinant (His) Human E. coli
CRIPT, also known as cysteine-rich PDZ-binding protein, belongs to the CRIPT family. It interacts with TUBB1. CRIPT also interacts strongly with the PDZ3 domain of members of the DLG4 family. It is involved in the cytosk...
TMPH-01798 Nucleolar transcription factor 1 Protein, Human, Recombinant (Cell-Free, His & SUMO) Human E. coli
Recognizes the ribosomal RNA gene promoter and activates transcription mediated by RNA polymerase I through cooperative interactions with the transcription factor SL1/TIF-IB complex. It binds specifically to the upstream...
TMPY-05503 Cripto Protein, Human, Recombinant (hFc) Human HEK293 Cells
Cripto Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 42.7 kDa and the accession number is P13385.
TMPH-01799 Nucleolar transcription factor 1 Protein, Human, Recombinant (E. coli, His & SUMO) Human E. coli
Recognizes the ribosomal RNA gene promoter and activates transcription mediated by RNA polymerase I through cooperative interactions with the transcription factor SL1/TIF-IB complex. It binds specifically to the upstream...
TMPK-00073 TDGF1/Cripto Protein, Human, Recombinant (His) Human HEK293 Cells
TDGF1 (CRIPTO) is a member of the epidermal growth factor-Cripto-1/FRL-1/Cryptic (EGF/CFC) gene family and an obligate co-receptor involved in NODAL signaling, a developmental program implicated in midline, forebrain, an...
Cat No. Product Name
L1380 Transcription Factor-Targeted Compound Library

695 compounds
Well-chosen 695 compounds with unique structures targeting transcription factor;
TargetMol