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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T12218 | NFAT Transcription Factor Regulator-1 | IL Receptor | |
NFAT Transcription Factor Regulator-1 is an synthesis inhibitor of IL-2 (IC50 of 182 nM). | |||
T6980 | Scriptaid | GCK1026,Scriptide | Apoptosis , Influenza Virus , HDAC , Autophagy |
Scriptaid (GCK1026) is an inhibitor of HDAC, and has a greater effect on acetylated H4 than H3. | |||
T5842 | Bromocriptine mesylate | CB-154 | Dopamine Receptor , Autophagy |
Bromocriptine mesylate (CB-154) is a potent dopamine receptor agonist that binds the D2 receptor with highest affinity (Ki = 2.5 nM) | |||
T12715 | Reverse transcriptase-IN-1 | HIV Protease | |
Reverse transcriptase-IN-1 is a diarylbenzopyrimidine (DABP) analogue and a potent inhibitor of HIV-1 nonnucleoside reverse transcriptase with an IC50of 13.7 nM. | |||
T72206 | Reverse transcriptase-IN-4 | ||
Reverse transcriptase-IN-4 is a potent, selective non-nucleoside reverse transcriptase (NNRT) inhibitor, demonstrating an EC50 of 0.053 μM against wild-type HIV-1 and 0.26 μM for the E138K HIV-1 mutant. | |||
T72203 | Reverse transcriptase-IN-3 | ||
Reverse transcriptase-IN-3, a pyrimidine-5-carboxamide derivative, functions as an inhibitor of HIV-1, demonstrating potent activity against both wild-type and mutant strains of HIV-1. | |||
T72658 | cRIPGBM chloride | ||
cRIPGBM chloride is an orally active, proapoptotic compound derived from glioblastoma multiforme (GBM) cancer stem cells (CSCs). It specifically targets receptor-interacting protein kinase 2 (RIPK2) to trigger caspase 1-... | |||
T68440 | Epicriptine | ||
Epicriptine or beta-dihydroergocryptine is a dopamine agonist of the ergoline class. It constitutes one third of the mixture known as dihydroergocryptine, the other two thirds consisting of alpha-dihydroergocryptine. The... | |||
TP2291 | Signal transducer and activator of transcription 6 fragment | Others | |
The signal transducer and activator of transcription 6 fragments is a peptide with the sequence H2N-Ser-Tyr-Trp-Ser-Asp-Arg-Leu-Ile-Ile-OH, MW= 1152.3. | |||
T40459 | Transcriptional Intermediary Factor 2 (TIF2) (740-753) | Transcriptional Intermediary Factor 2 (TIF2) (740-753) | |
Transcriptional Intermediary Factor 2 (TIF2) (740-753) is a 14-amino acid peptide that serves as a coactivator of TIF-2 protein. It specifically covers residues 740-753 of the TIF-2 protein. | |||
T19250 | cRIPGBM | TNF | |
cRIPGBM, a proapoptotic derivative of RIPGBM, selectively induces apoptosis in GBM cancer stem cells (CSCs) by targeting receptor-interacting protein kinase 2 (RIPK2), demonstrating an EC50 of 68 nM in GBM-1 cells [1]. |
Cat No. | Product Name | Species | Expression System |
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TMPY-03342 | CRIP2 Protein, Human, Recombinant (His & GST) | Human | Baculovirus Insect Cells |
CRIP2 Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 50.3 kDa and the accession number is P52943. | |||
TMPY-03459 | CRIP2 Protein, Human, Recombinant | Human | Baculovirus Insect Cells |
CRIP2 Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 22.6 kDa and the accession number is P52943. | |||
TMPY-01413 | Cripto Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Cripto Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.4 kDa and the accession number is AAH22393.1. | |||
TMPY-02679 | Cripto Protein, Rat, Recombinant (hFc) | Rat | HEK293 Cells |
Cripto Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 41 kDa and the accession number is XP_001056317.2. | |||
TMPY-03908 | Cripto Protein, Rat, Recombinant (His) | Rat | HEK293 Cells |
Cripto Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.5 kDa and the accession number is XP_001056317.2. | |||
TMPY-03750 | CRIPT Protein, Human, Recombinant (His) | Human | E. coli |
CRIPT, also known as cysteine-rich PDZ-binding protein, belongs to the CRIPT family. It interacts with TUBB1. CRIPT also interacts strongly with the PDZ3 domain of members of the DLG4 family. It is involved in the cytosk... | |||
TMPH-01798 | Nucleolar transcription factor 1 Protein, Human, Recombinant (Cell-Free, His & SUMO) | Human | E. coli |
Recognizes the ribosomal RNA gene promoter and activates transcription mediated by RNA polymerase I through cooperative interactions with the transcription factor SL1/TIF-IB complex. It binds specifically to the upstream... | |||
TMPY-05503 | Cripto Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
Cripto Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 42.7 kDa and the accession number is P13385. | |||
TMPH-01799 | Nucleolar transcription factor 1 Protein, Human, Recombinant (E. coli, His & SUMO) | Human | E. coli |
Recognizes the ribosomal RNA gene promoter and activates transcription mediated by RNA polymerase I through cooperative interactions with the transcription factor SL1/TIF-IB complex. It binds specifically to the upstream... | |||
TMPK-00073 | TDGF1/Cripto Protein, Human, Recombinant (His) | Human | HEK293 Cells |
TDGF1 (CRIPTO) is a member of the epidermal growth factor-Cripto-1/FRL-1/Cryptic (EGF/CFC) gene family and an obligate co-receptor involved in NODAL signaling, a developmental program implicated in midline, forebrain, an... |
Cat No. | Product Name | ||
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L1380 | Transcription Factor-Targeted Compound Library | 695 compounds | |
Well-chosen 695 compounds with unique structures targeting transcription factor; |