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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T82700 | Cn2 toxin | β-Mammal toxin Cn2 | |
Cn2 toxin, a β-toxin, interacts with the voltage-sensing domain of voltage-gated sodium channels (NaV) [1]. | |||
T11373 | GCN2-IN-1 | A-92 | Others |
GCN2-IN-1 (A-92) is an effective GCN2 inhibitor and can be used in research on the treatment of cancer as a chemotherapeutic agent. | |||
T11374 | GCN2-IN-6 | Others , PERK | |
GCN2-IN-6 is also a eIF2α kinase PERK inhibitor with an IC50 of 0.26 nM (in enzymatic assay) and 230 nM (in cells). GCN2-IN-6 is a potent, and orally available GCN2 inhibitor confirmed by in-house enzymatic (IC50 of 1.8... | |||
T7494 | TCN238 | TCN 238 | GluR |
TCN238 is an orally bioavailable positive allosteric modulator of the metabotropic glutamate receptor 4 (mGluR4with an EC50 of 1 μM). | |||
T11375 | GCN2iB | Others , Autophagy | |
GCN2iB is an ATP-competitive inhibitor of a serine/threonine-protein kinase general control nonderepressible 2 (GCN2), with an IC50 of 2.4 nM. | |||
T63699 | GCN2-IN-7 | ||
GCN2-IN-7 is a selective, orally active general control nonderepressible 2 (GCN2) inhibitor with an IC50 value of 5 nM that exhibits antitumor effects in vivo. | |||
T69829 | GCN2iB acetate | ||
GCN2iB is a GCN2 inhibitor. GCN2iB may be useful for the treatment of cancer. The inhibition of GCN2 sensitizes cancer cells with low basal-level expression of asparagine synthetase (ASNS) to the antileukemic agent L-as... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-00361 | Beta-mammal toxin Cn2 Protein, Centruroides noxius, Recombinant (His) | Centruroides noxius | P. pastoris (Yeast) |
Mammal beta-toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the activation voltage to more negative potentials. This toxin is active against mammals. Beta-mammal toxin Cn2 Protein, Centruro... | |||
TMPY-01773 | CNDP2 Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
CNDP2 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 54.2 kDa and the accession number is CAC69883.1. | |||
TMPH-01199 | CNDP2 Protein, Human, Recombinant (E. coli, His) | Human | E. coli |
CNDP2 Protein, Human, Recombinant (E. coli, His) is expressed in E. coli. | |||
TMPY-01739 | CNDP2 Protein, Mouse, Recombinant (His) | Mouse | Baculovirus Insect Cells |
CNDP2 Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 54.22 kDa and the accession number is Q9D1A2. | |||
TMPY-00988 | Lipocalin-2/LCN2 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Lipocalin-2/LCN2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22.3 kDa and the accession number is P11672. | |||
TMPY-00873 | Lipocalin-2/LCN2 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Lipocalin-2/LCN2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22.7 kDa and the accession number is P80188-1. | |||
TMPY-01003 | TCN2 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
TCN2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46.7 kDa and the accession number is P20062-1. | |||
TMPK-00672 | CTGF/CCN2 Protein, Rhesus macaque, Recombinant (His) | Rhesus | HEK293 Cells |
Connective tissue growth factor (CTGF) is a member of the CCN matricellular protein family, consisting of four domains, that regulates the signaling of other growth factors and promotes kidney fibrosis.CTGF can simultane... | |||
TMPJ-01162 | CTGF/CCN2 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
CTGF/CCN2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 67-81 KDa and the accession number is Q5M8T4. | |||
TMPJ-01163 | CTGF/CCN2 Protein, Human, Recombinant (HEK293, His) | Human | HEK293 Cells |
Connective Tissue Growth Factor (CTGF), also known as CCN2, is a member of the CCN (CYR61/CTGF/NOV) family of secreted matricellular proteins. Like other CCN proteins, mature human CTGF consists of IGF-binding protein d... | |||
TMPY-03697 | SCN2B Protein, Human, Recombinant (His) | Human | HEK293 Cells |
SCN2B Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 34.7 kDa and the accession number is O60939. | |||
TMPY-02192 | TCN2 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
TCN2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 47 kDa and the accession number is O88968. | |||
TMPY-05203 | Lipocalin-2/LCN2 Protein, Mouse, Recombinant | Mouse | HEK293 Cells |
Lipocalin-2/LCN2 Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 20.9 kDa and the accession number is P11672. | |||
TMPK-01000 | CTGF/CCN2 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 Cells |
Connective tissue growth factor (CTGF) is a member of the CCN matricellular protein family, consisting of four domains, that regulates the signaling of other growth factors and promotes kidney fibrosis.CTGF can simultane... | |||
TMPH-01069 | CTGF/CCN2 Protein, Human, Recombinant (His) | Human | E. coli |
Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types ... | |||
TMPY-03183 | SCN2B Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
SCN2B Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 42.2 kDa and the accession number is O60939. | |||
TMPH-02568 | CTGF/CCN2 Protein, Mouse, Recombinant (GST) | Mouse | E. coli |
Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types ... | |||
TMPJ-01113 | RCN2 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Reticulocalbin-2 (RCN2, also named as ERC-55), is a 55-kDa Ca2+-binding protein containing six EF-hands, which was identified to be localized in endoplasmic reticulum. RCN2 is belonging to Reticulocalbin (RCN) family, th... | |||
TMPJ-01161 | CTGF/CCN2 Protein, Human, Recombinant | Human | HEK293 Cells |
CTGF/CCN2 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 16-25 KDa and the accession number is Q5M8T4. | |||
TMPY-02316 | Lipocalin-2/LCN2 Protein, Rat, Recombinant (His) | Rat | Baculovirus Insect Cells |
Lipocalin-2/LCN2 Protein, Rat, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 21.9 kDa and the accession number is P30152. |