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Search Results for " bmps "

Targets

4

Compounds

9

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T14668 BMPS Others
BMPS, a non-cleavable ADC linker, is utilized in the synthesis of antibody-drug conjugates (ADCs).
T1944 LDN-214117 ALK , TGF-beta/Smad
LDN-214117 is a potent and selective ALK2 inhibitor.
T30486 BMPSP
BMPSP is a fluorescent DNA groove binding probe.
T23127 PD-161570 PD 161570 EGFR , FGFR , PDGFR , Src
PD-161570 is a potent and ATP-competitive human FGF-1 receptor inhibitor with an IC50 of 39.9 nM and a Ki of 42 nM. PD-161570 also inhibits the PDGFR, EGFR and c-Src tyrosine kinases with IC50 values of 310 nM, 240 nM, a...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPH-01079 CLN5 Protein, Human, Recombinant (His) Human E. coli
Plays a role in influencing the retrograde trafficking of lysosomal sorting receptors SORT1 and IGF2R from the endosomes to the trans-Golgi network by controlling the recruitment of retromer complex to the endosomal memb...
TMPJ-01065 Noggin/NOG Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
Noggin is a secreted homodimeric glycoprotein that is an antagonist of bone morphogenetic proteins (BMPs). Mouse Noggin cDNA encodes a 232 amino acid (aa) residue precursor protein with 19 aa residue putative signal pept...
TMPH-02552 BMP3 Protein, Mouse, Recombinant (Myc) Mouse E. coli
Negatively regulates bone density. Antagonizes the ability of certain osteogenic BMPs to induce osteoprogenitor differentitation and ossification.
TMPY-01817 GDF-10 Protein, Mouse, Recombinant (hFc) Mouse HEK293 Cells
BMP-3b / GDF-10 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a ma...
TMPJ-01322 TWSG1 Protein, Human, Recombinant (His) Human HEK293 Cells
Twisted Gastrulation Protein Homolog 1 (TWSG1) is a 22 kDa secreted protein that belongs to the twisted gastrulation protein family. Human TWSG1 is synthesized as a 223 aa precursor that contains a 25 aa signal peptide a...
TMPJ-00521 CHL2 Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
Mouse Chordin-Like 2, also known as CHL2, is a novel chordin family member with structural homology to CHL1 which is implicated in tumor angiogenesis. The mouse CHL2 gene encodes a 426 amino acids (aa) protein with a 25...
TMPY-00681 BMP-5 Protein, Human, Recombinant (hFc) Human HEK293 Cells
Bone Morphogenetic Protein 5 (BMP-5) is a member of the structurally and functionally related bone morphogenetic proteins (BMPs) which constitute a novel subfamily of the transforming growth factor β (TGF-β) superfamily....
TMPH-01015 BMP-3 Protein, Human, Recombinant (His) Human E. coli
Growth factor of the TGF-beta superfamily that plays an essential role in developmental process by inducing and patterning early skeletal formation and by negatively regulating bone density. Antagonizes the ability of ce...
TMPJ-01177 NOV/CCN3 Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
NOV, also called CCN3, is a secreted protein of CCN family members. CCN family members are highly conserved cysteine rich proteins sharing a common modular structure having 4 conserved domains, insulin-like growth factor...
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