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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T14668 | BMPS | Others | |
BMPS, a non-cleavable ADC linker, is utilized in the synthesis of antibody-drug conjugates (ADCs). | |||
T1944 | LDN-214117 | ALK , TGF-beta/Smad | |
LDN-214117 is a potent and selective ALK2 inhibitor. | |||
T30486 | BMPSP | ||
BMPSP is a fluorescent DNA groove binding probe. | |||
T23127 | PD-161570 | PD 161570 | EGFR , FGFR , PDGFR , Src |
PD-161570 is a potent and ATP-competitive human FGF-1 receptor inhibitor with an IC50 of 39.9 nM and a Ki of 42 nM. PD-161570 also inhibits the PDGFR, EGFR and c-Src tyrosine kinases with IC50 values of 310 nM, 240 nM, a... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-01079 | CLN5 Protein, Human, Recombinant (His) | Human | E. coli |
Plays a role in influencing the retrograde trafficking of lysosomal sorting receptors SORT1 and IGF2R from the endosomes to the trans-Golgi network by controlling the recruitment of retromer complex to the endosomal memb... | |||
TMPJ-01065 | Noggin/NOG Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Noggin is a secreted homodimeric glycoprotein that is an antagonist of bone morphogenetic proteins (BMPs). Mouse Noggin cDNA encodes a 232 amino acid (aa) residue precursor protein with 19 aa residue putative signal pept... | |||
TMPH-02552 | BMP3 Protein, Mouse, Recombinant (Myc) | Mouse | E. coli |
Negatively regulates bone density. Antagonizes the ability of certain osteogenic BMPs to induce osteoprogenitor differentitation and ossification. | |||
TMPY-01817 | GDF-10 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 Cells |
BMP-3b / GDF-10 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a ma... | |||
TMPJ-01322 | TWSG1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Twisted Gastrulation Protein Homolog 1 (TWSG1) is a 22 kDa secreted protein that belongs to the twisted gastrulation protein family. Human TWSG1 is synthesized as a 223 aa precursor that contains a 25 aa signal peptide a... | |||
TMPJ-00521 | CHL2 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Mouse Chordin-Like 2, also known as CHL2, is a novel chordin family member with structural homology to CHL1 which is implicated in tumor angiogenesis. The mouse CHL2 gene encodes a 426 amino acids (aa) protein with a 25... | |||
TMPY-00681 | BMP-5 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
Bone Morphogenetic Protein 5 (BMP-5) is a member of the structurally and functionally related bone morphogenetic proteins (BMPs) which constitute a novel subfamily of the transforming growth factor β (TGF-β) superfamily.... | |||
TMPH-01015 | BMP-3 Protein, Human, Recombinant (His) | Human | E. coli |
Growth factor of the TGF-beta superfamily that plays an essential role in developmental process by inducing and patterning early skeletal formation and by negatively regulating bone density. Antagonizes the ability of ce... | |||
TMPJ-01177 | NOV/CCN3 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
NOV, also called CCN3, is a secreted protein of CCN family members. CCN family members are highly conserved cysteine rich proteins sharing a common modular structure having 4 conserved domains, insulin-like growth factor... |