aurora — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T5524	Aurora kinase inhibitor-3	Aurora Kinase Inhibitor III	Aurora Kinase
	Aurora kinase inhibitor-3 (Aurora Kinase Inhibitor III) is a potent inhibitor of Aurora A kinase (IC50 = 42 nM).1 It is selective for Aurora A over BMX, BTK, IGF-1R, c-Src, TRKB, SYK, and EGFR.		Aurora Kinase
T9040	Aurora kinase inhibitor-2	IUN-70219,Aurora Kinase Inhibitor II	Aurora Kinase
	Aurora kinase inhibitor-2 (IUN-70219) is a cell-permeable anilinoquinazoline that inhibit the activity of Aurora A (IC50 = 0.39 M).		Aurora Kinase
T12010	Aurora B inhibitor 1		Aurora Kinase
	Aurora B inhibitor 1 is an Aurora B (Aurora-1) inhibitor (Ki <0.010 uM) with potential anticancer activity for cancer research.		Aurora Kinase
T6767	TCS7010	Aurora A Inhibitor I	Apoptosis , Aurora Kinase
	TCS7010 (Aurora A Inhibitor I) is a novel, potent, and selective inhibitor of Aurora A with IC50 of 3.4 nM in a cell-free assay. It is 1000-fold more selective for Aurora A than Aurora B.		Apoptosis , Aurora Kinase
T10412	Aurora inhibitor 1		Aurora Kinase
	Aurora inhibitor 1 is a potent Aurora inhibitor (IC50: ≤ 4 nM and ≤13 nM for Aurora A and Aurora B kinase).		Aurora Kinase
T23044	N,N'-Dicyclohexylurea	DCU,1,3-Dicyclohexylurea,NSC 17013,Dicyclohexylurea,Dicyclohexylcarbodiamide,AURORA KA-3582	Epoxide Hydrolase
	N,N'-Dicyclohexylurea (AURORA KA-3582) is a soluble epoxide hydrolase (sEH) inhibitor.		Epoxide Hydrolase
T78753	Aurora Kinases-IN-4		Aurora Kinase
	Aurora Kinases-IN-4 (Compound 11c) is a covalent, ATP-competitive inhibitor of aurora kinase A with an IC50 value of 1.7 nM. It demonstrates cell proliferation inhibition in SJSA-1, MDA-MB-231, A549, and HeLa cell lines ...		Aurora Kinase
T63773	Aurora kinase inhibitor-8
	Aurora kinase inhibitor-8 is a highly selective inhibitor of Aurora kinase.
T62789	Aurora kinase inhibitor-9
	Aurora kinase inhibitor-9 (compound 9d) is a potent AURKA/B bipolar kinase inhibitor, acting on Aurora A (IC50: 0.093 μM), Aurora B (IC50: 0.09 μM). broad-spectrum anti-proliferative activity.
T82931	Aurora A inhibitor 3		Aurora Kinase
	Aurora A Inhibitor 3 (Compound 5h) effectively inhibits Aurora-A kinase, exhibiting an IC50 of 0.78 μM, and demonstrates cytotoxicity against MCF-7 and MDA-MB-231 cell lines with GI50 values of 0.12 μM and 0.63 μM, respe...		Aurora Kinase
T72522	Aurora kinase-IN-1
	Aurora kinase-IN-1, a potent aurora kinase inhibitor, modulates cell cycle progression and induces apoptosis by upregulating G1 cell cycle inhibitory proteins (including p21 and p27), elevating G1 progressive cyclin D1, ...
T72504	Aurora Kinases-IN-3
	Aurora Kinases-IN-3, an orally active inhibitor of AURKB, suppresses AURKB activity by hindering its mitotic localization rather than by inhibiting its phosphorylation of H3 at Ser10.
T62484	Aurora Kinases-IN-2
	Aurora Kinases-IN-2 (compound 12Aj) is a potent inhibitor of Aurora kinases, acting on Aurora A (IC50: 90 nM) and Aurora B (IC50: 152 nM). Aurora Kinases-IN-2 can be used in cancer research.
T63436	Aurora A inhibitor 1
	Aurora A inhibitor 1 is a potent and selective Aurora A inhibitor. Aurora A is associated with cancers of multiple histological origins and may exhibit oncogenic activity when overexpressed. aurora A inhibitor 1 exhibits...
T62647	Aurora A inhibitor 2
	Aurora A inhibitor 2 (Compound 16h) is a potent inhibitor of Aurora A kinase (IC50: 21.94 nM).
T63853	Aurora kinase inhibitor-10
	Aurora kinase inhibitor-10 is an orally active Aurora B inhibitor (IC50: 8 nM) that exhibits antitumour effects.
T60783	Aurora/LIM kinase-IN-1
	Aurora/LIM kinase-IN-1 (Compound F114) is a potent aurora and lim kinase dual inhibitor. Aurora/LIM kinase-IN-1 inhibits the proliferation and invasion of GBM that may be used in drug development efforts for GBM, further...
T62945	Aurora A/PKC-IN-1
	Aurora A/PKC-IN-1 (Compound 2e) is a potent dual inhibitor of Aurora A (AurA) and PKC (α, β1, β2, θ), acting on AurA (IC50: 6.9 nM) and PKCα (IC50: 16.9 nM). Aurora A/PKC-IN-1 showed anti-proliferative and anti-metastati...
T6532	Hesperadin		Influenza Virus , Parasite , Aurora Kinase , Autophagy
	Hesperadin(IC50=250 nM) effectively inhibits Aurora B. It potently reduces the activity of AMPK, MAPKAP-K1, MKK1, Lck, CHK1 and PHK, but it could not inhibit MKK1 activity in vivo.		Influenza Virus , Parasite , Aurora Kinase , Autophagy
T1825	Reversine		Aurora Kinase , Adenosine Receptor , Autophagy
	Reversine, a small synthetic purine analogue (2, 6-disubstituted purine), is a potent inhibitior of Aurora A/B/C(IC50s=150-500 nM).		Aurora Kinase , Adenosine Receptor , Autophagy