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Search Results for " ara-c "

9

Compounds

Cat No. Product Name Synonyms Targets
T1272L Cytarabine hydrochloride Ara-C hydrochloride,Cytosine Arabinoside hydrochloride DNA/RNA Synthesis
Cytarabine hydrochloride (Ara-C hydrochloride) is a nucleoside analog that causes S phase cell cycle arrest and inhibits DNA polymerase. Cytarabine inhibits DNA synthesis with an IC 50 of 16 nM. Cytarabine hydrochloride ...
T1272 Cytarabine Ara-C,Cytosine Arabinoside,Cytosine β-D-arabinofuranoside,Arabinocytidine Apoptosis , Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis , Endogenous Metabolite , Autophagy , HSV
Cytarabine (Ara-C) is a nucleoside analog, an inhibitor of DNA synthesis (IC50=16 nM). Cytarabine inhibits DNA polymerase and induces cell cycle arrest, autophagy, and apoptosis. Cytarabine has antitumor activity.
TNU1176 2’-Fluoro-2’-deoxy-ara-C(Bz)-3’-phosphoramidite
2'-Fluoro-2'-deoxy-ara-C(Bz)-3'-phosphoramidite is a Nucleoside Phosphoramidite; Nucleoside Derivative - Fluoro-modified nucleoside.
TP1828 N-Acetyl-Ser-Asp-Lys-Pro RAAS
Acetyl Ser-Asp-Lys-Pro is formed in bone marrow cells by enzymatic processing of thymosin β4. It inhibits the entry of pluripotent hemopoietic stem cells into S-phase of the cell cycle and protects against Ara-C lethalit...
T8308 NL-1 Mitochondrial Metabolism , Autophagy
NL-1 is a mitoNEET inhibitor with antileukemic effect.
T36944 Ara-G Nucleoside Antimetabolite/Analog
Ara-G is an analog of the nucleoside guanosine and an active metabolite of nelarabine .1,2 Ara-G accumulates in T lymphoblasts and malignant T-lymphoid cells, where it is phosphorylated to produce ara-GTP and incorporate...
T11957 MBC-11 trisodium Others
MBC-11 trisodium has potential to treat tumor-induced bone disease (TIBD).It is a first-in-class conjugate of the bone-targeting bisphosphonate HEDP covalently linked to the antimetabolite Ara-C.
T17059 Tetrahydrouridine NSC 112907,NSC112907,NSC-112907 DNA Methyltransferase
Tetrahydrouridine (NSC-112907; THU) is a multidrug resistance modulator. It can be used in cancer treatment to make tumor cells more sensitive to radiation therapy. THU is a competitive cytidine deaminase(CDA) inhibitor ...
T71361 CHS-828 nicotinate
CHS-828 nicotinate is a CHS-828 salt with Nicotinic acid.. CHS-828 also known as GMX-1778, is a potent and selective NAMPT inhibitor. CHS-828 inhibits cellular synthesis of NAD. CHS 828 kill tumour cells by inhibiting ...
TargetMol