9
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T1272L | Cytarabine hydrochloride | Ara-C hydrochloride,Cytosine Arabinoside hydrochloride | DNA/RNA Synthesis |
Cytarabine hydrochloride (Ara-C hydrochloride) is a nucleoside analog that causes S phase cell cycle arrest and inhibits DNA polymerase. Cytarabine inhibits DNA synthesis with an IC 50 of 16 nM. Cytarabine hydrochloride ... | |||
T1272 | Cytarabine | Ara-C,Cytosine Arabinoside,Cytosine β-D-arabinofuranoside,Arabinocytidine | Apoptosis , Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis , Endogenous Metabolite , Autophagy , HSV |
Cytarabine (Ara-C) is a nucleoside analog, an inhibitor of DNA synthesis (IC50=16 nM). Cytarabine inhibits DNA polymerase and induces cell cycle arrest, autophagy, and apoptosis. Cytarabine has antitumor activity. | |||
TNU1176 | 2’-Fluoro-2’-deoxy-ara-C(Bz)-3’-phosphoramidite | ||
2'-Fluoro-2'-deoxy-ara-C(Bz)-3'-phosphoramidite is a Nucleoside Phosphoramidite; Nucleoside Derivative - Fluoro-modified nucleoside. | |||
TP1828 | N-Acetyl-Ser-Asp-Lys-Pro | RAAS | |
Acetyl Ser-Asp-Lys-Pro is formed in bone marrow cells by enzymatic processing of thymosin β4. It inhibits the entry of pluripotent hemopoietic stem cells into S-phase of the cell cycle and protects against Ara-C lethalit... | |||
T8308 | NL-1 | Mitochondrial Metabolism , Autophagy | |
NL-1 is a mitoNEET inhibitor with antileukemic effect. | |||
T36944 | Ara-G | Nucleoside Antimetabolite/Analog | |
Ara-G is an analog of the nucleoside guanosine and an active metabolite of nelarabine .1,2 Ara-G accumulates in T lymphoblasts and malignant T-lymphoid cells, where it is phosphorylated to produce ara-GTP and incorporate... | |||
T11957 | MBC-11 trisodium | Others | |
MBC-11 trisodium has potential to treat tumor-induced bone disease (TIBD).It is a first-in-class conjugate of the bone-targeting bisphosphonate HEDP covalently linked to the antimetabolite Ara-C. | |||
T17059 | Tetrahydrouridine | NSC 112907,NSC112907,NSC-112907 | DNA Methyltransferase |
Tetrahydrouridine (NSC-112907; THU) is a multidrug resistance modulator. It can be used in cancer treatment to make tumor cells more sensitive to radiation therapy. THU is a competitive cytidine deaminase(CDA) inhibitor ... | |||
T71361 | CHS-828 nicotinate | ||
CHS-828 nicotinate is a CHS-828 salt with Nicotinic acid.. CHS-828 also known as GMX-1778, is a potent and selective NAMPT inhibitor. CHS-828 inhibits cellular synthesis of NAD. CHS 828 kill tumour cells by inhibiting ... |