Search Result

Search Results for " apn "

Targets

Compounds

Natural Products

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
T14311	APN-NH2		Others
	APN- NH2 is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].		Others
T17453	APN-PEG4-tetrazine		Others
	APN-PEG4-tetrazine is a cleavable ADC linker compound comprised of four PEG units, specifically designed for the synthesis of antibody-drug conjugates (ADCs)[1].		Others
T17451	APN-PEG4-DBCO		Others
	APN-PEG4-DBCO is a cleavable linker for antibody-drug conjugates (ADCs), comprised of a four-unit PEG and a DBCO moiety. It finds application in the synthesis of ADCs[1].		Others
T14310	APN-C3-PEG4-azide		Others
	APN-C3-PEG4-azide is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system...		Others
T17450	APN-PEG4-BCN		Others
	APN-PEG4-BCN is a cleavable four-unit polyethylene glycol (PEG) linker, employed in the synthesis of antibody-drug conjugates (ADCs)[1].		Others
T17452	APN-PEG4-PFP		Others
	APN-PEG4-PFP is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system with...		Others
T14309	APN-C3-PEG4-alkyne		Others
	APN-C3-PEG4-alkyne is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome syste...		Others
T17449	APN-PEG4-Amine hydrochloride		Others
	APN-PEG4-Amine (hydrochloride) is a cleavable four-unit polyethylene glycol (PEG) linker utilized in the synthesis of antibody-drug conjugates (ADCs)[1].		Others
T14308	APN-C3-NH-Boc	tert-Butyl 3-(4-(2-cyanoethynyl)phenylcarbamoyl)propylcarbamate	Others
	APN-C3-NH-Boc is a alkyl/ether-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome sy...		Others
T77836	APN-PEG36-tetrazine
	APN-PEG36-tetrazine, an analogue of APN-PEG4-tetrazine, serves as a cleavable polyethylene glycol (PEG) linker with 36 units, facilitating the synthesis of antibody-drug conjugates (ADCs) [1].
T61756	APN/AKT-IN-1
	APN/AKT-IN-1 is a potent dual inhibitor of aminopeptidase N (APN) and protein kinase B (AKT), exhibiting IC50 values of 0.21 μM and 0.27 μM for APN and AKT inhibition, respectively. This compound effectively suppresses t...
T12159	APNEA	(2R,3R,4S,5R)-2-[6-[2-(4-aminophenyl)ethylamino]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol,N6-[2-(4-Aminophenyl)ethyl]adenosine	Adenosine Receptor
	APNEA ((2R,3R,4S,5R)-2-[6-[2-(4-aminophenyl)ethylamino]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol) is a non-selective agonist of adenosine A3 receptor.		Adenosine Receptor
T9321	Zapnometinib	ATR-002,3,4-difluoro-2-(2-chloro-4-iodophenylaMino)-benzoic acid,PD0184264,2-(2-chloro-4-iodoanilino)-3,4-difluorobenzoic acid	Influenza Virus , MEK , Antibacterial
	Zapnometinib (ATR-002) is a MEK inhibitor.		Influenza Virus , MEK , Antibacterial
T23850	Capnoidine	l-Capnoidine,l-Adlumidine,(-)-Adlumidine
	Capnoidine is a potential new anti-inflammatory drug lead candidate for diseases where current standard-of-care often fails and is associated with major side effects.
T124692	Capnolactone
	Capnolactone is a useful organic compound for research related to life sciences. The catalog number is T124692 and the CAS number is 53771-63-4.
T27136	Debio-0827	PL37,PL-37,PL 37,Debio0827
	Debio-0827, a NEP and APN inhibitor, is used potentially for treatment of pain.
TP1771	NGR peptide Trifluoroacetate
	NGR peptide Trifluoroacetate containing the asparagine-glycine-arginine (NGR) motif is recognized by CD13/aminopeptidase N (APN) receptor isoforms that are selectively overexpressed in tumor neovasculature.
T38641	AP 811
	AP 811, a selective antagonist of the atrial natriuretic peptide clearance receptor (APN-CR, NPR3) with a K i value of 0.48 nM, exhibits remarkable selectivity for NPR3 over NPR1 by more than 20,000-fold. Moreover, AP 81...

Compounds

APN-PEG4-Amine hydrochloride

Synonym: tert-Butyl 3-(4-(2-cyanoethynyl)phenylcarbamoyl)propylcarbamate

Target: Others

APN-PEG36-tetrazine

Synonym: (2R,3R,4S,5R)-2-[6-[2-(4-aminophenyl)ethylamino]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol,N6-[2-(4-Aminophenyl)ethyl]adenosine

Target: Adenosine Receptor

zapnometinib

T9321

Synonym: ATR-002,3,4-difluoro-2-(2-chloro-4-iodophenylaMino)-benzoic acid,PD0184264,2-(2-chloro-4-iodoanilino)-3,4-difluorobenzoic acid

Target: Influenza Virus, MEK, Antibacterial

Capnoidine

T23850

Synonym: l-Capnoidine,l-Adlumidine,(-)-Adlumidine

Synonym: PL37,PL-37,PL 37,Debio0827

Target:

NGR peptide Trifluoroacetate

Cat No.	Product Name	Synonyms	Targets
T3529	Bestatin hydrochloride	Ubenimex hydrochloride	Integrin , Aminopeptidase , Antibacterial , Antibiotic
	Bestatin hydrochloride (Ubenimex hydrochloride) is an inhibitor of aminopeptidase N (APN)/CD13 and aminopeptidase B.		Integrin , Aminopeptidase , Antibacterial , Antibiotic
T1257	Bestatin	Ubenimex	Others , Aminopeptidase , Antibacterial , Antibiotic , LTR
	Bestatin (Ubenimex) competitively inhibits many aminopeptidases, including B, N and leucine aminopeptidases. Ubenimex is a microbial metabolite and dipeptide with potential immunomodulatory and antitumor activities. Amin...		Others , Aminopeptidase , Antibacterial , Antibiotic , LTR
T62258	Bestatin trifluoroacetate
	Bestatin trifluoroacetate (Ubenimex trifluoroacetate) is a CD13 (Aminopeptidase N)/APN and leukotriene A4 hydrolase inhibitor that is often used in cancer research.

Natural Products

Bestatin hydrochloride

T3529

Synonym: Ubenimex hydrochloride

Target: Integrin, Aminopeptidase, Antibacterial, Antibiotic

Bestatin

T1257

Synonym: Ubenimex

Target: Others, Aminopeptidase, Antibacterial, Antibiotic, LTR

Bestatin trifluoroacetate

T62258

Synonym:

Target:

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-00665	Aminopeptidase N/CD13 Protein, Human, Recombinant (I603M, His)	Human	HEK293 Cells
	Aminopeptidase N/CD13 Protein, Human, Recombinant (I603M, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 104.2 kDa and the accession number is A0A024RC61.
TMPY-00758	Aminopeptidase N/CD13 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Aminopeptidase N/CD13 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 104 kDa and the accession number is P97449.
TMPY-01681	Adiponectin Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Adiponectin Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.4 kDa and the accession number is Q60994.
TMPH-01031	CAPN2 Protein, Human, Recombinant (His)	Human	E. coli
	Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Proteolytically cleaves MYOC at 'Arg-226'. Proteolytically cle...
TMPH-01029	CAPN1 Protein, Human, Recombinant (His)	Human	E. coli
	Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Proteolytically cleaves CTBP1 at 'Asn-375', 'Gly-387' and 'His...
TMPH-01673	Human metapneumovirus (strain CAN97-83) Matrix protein (His)	HMPV	P. pastoris (Yeast)
	Plays a crucial role in virus assembly into filaments and budding. Early in infection, localizes in the nucleus where it may inhibit host cell transcription. Later in infection, traffics to the cytoplasm through the acti...
TMPH-00060	ApNPV Viral cathepsin Protein (His & Myc)	ApNPV	E. coli
	Cysteine protease that plays an essential role in host liquefaction to facilitate horizontal transmission of the virus. May participate in the degradation of foreign protein expressed by the baculovirus system. ApNPV Vir...
TMPY-06206	Human metapneumovirus (strain HMPV/Homo sapiens/PER/CFI0466/2010/B) glycoprotein G Protein (His)	HMPV	HEK293 Cells
	Human metapneumovirus (strain HMPV/Homo sapiens/PER/CFI0466/2010/B) glycoprotein G Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 21.6 kDa and the accession number is...
TMPH-02557	CAPN1 Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Proteolytically cleaves CTBP1 at 'Asn-375', 'Gly-388' and 'His...
TMPH-01674	Human metapneumovirus (strain CAN97-83) Nucleoprotein/NP Protein (His & Myc)	HMPV	E. coli
	Encapsidates the viral RNA genome by forming a left-handed helical nucleocapsid that protects the RNA from nucleases. RNA replication depends on the availability of soluble nucleoprotein. The encapsidated genomic RNA is ...
TMPH-01672	Human metapneumovirus (strain CAN97-83) Matrix protein (His & Myc)	HMPV	E. coli
	Plays a crucial role in virus assembly into filaments and budding. Early in infection, localizes in the nucleus where it may inhibit host cell transcription. Later in infection, traffics to the cytoplasm through the acti...
TMPH-01030	CAPN14 Protein, Human, Recombinant (His & Myc)	Human	Baculovirus Insect Cells
	Calcium-regulated non-lysosomal thiol-protease. CAPN14 Protein, Human, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 78.6 kDa and the acce...
TMPY-06207	Human metapneumovirus (strain HMPV/Homo sapiens/PER/CFI0320/2010/A) glycoprotein G Protein (His)	HMPV	HEK293 Cells
	Human metapneumovirus (strain HMPV/Homo sapiens/PER/CFI0320/2010/A) glycoprotein G Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20.4 kDa and the accession number is...
TMPH-01671	Human metapneumovirus (strain CAN97-83) Fusion glycoprotein F0 (His & SUMO)	HMPV	E. coli
	Inactive precursor that is cleaved to give rise to the mature F1 and F2 fusion glycoproteins.; Class I viral fusion protein. Under the current model, the protein has at least 3 conformational states: pre-fusion native st...
TMPY-06885	SARS-CoV-2 XBB.1.16 (Omicron) Spike S1+S2 trimer Protein (ECD, His)
	The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2; DPP4, dipeptidyl peptidase-4;...