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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T40711 | H-D-Phe-Pip-Arg-pNA dihydrochloride | S-2238 dihydrochloride,H-D-Phe-Pip-Arg-pNA dihydrochloride | Others |
H-D-Phe-Pip-Arg-pNA dihydrochloride (S-2238 dihydrochloride), a chromogenic substrate, mimics the N-terminal fragment of the A alpha chain of fibrinogen, the native substrate of thrombin. Specifically designed for thromb... | |||
T9011 | VU0155094 | ML 397,ML-397,VU 0155094,VU-0155094 | GluR |
VU0155094 (ML 397) is a positive allosteric modulator with differential activity at the various group III mGluRs. | |||
TL0007 | Bisdemethoxycurcumin | Curcumin III,Didemethoxycurcumin | Epigenetic Reader Domain , Wnt/beta-catenin |
Bisdemethoxycurcumin (Curcumin III) is a natural demethoxy derivative of curcumin. It is a potent activator of macrophage phagocytosis, interacting with 1α, 25-dihydroxy vitamin D3 to stimulate amyloid-β clearance by mac... | |||
T39066 | H-D-Phe-Pip-Arg-pNA hydrochloride | S-2238 hydrochloride,H-D-Phe-Pip-Arg-pNA hydrochloride | |
H-D-Phe-Pip-Arg-pNA hydrochloride, a chromogenic substrate, mimics the N-terminal segment of the A alpha chain of fibrinogen, the native substrate of thrombin. It displays specificity towards thrombin and is employed for... | |||
T27444 | GSK 932121 | GSK-932121,GSK932121 | |
GSK 932121 is a potent antimalarial agent. GSK 932121 inhibits selectively the electron-transport chain in P. falciparum at the cytochrome bc1 level (complex III). | |||
T37851 | Chlorido[N,N'-disalicylidene-1,2-phenylenediamine]iron(III) | ||
Chlorido[N,N'-disalicylidene-1,2-phenylenediamine]iron(III) is an inducer of ferroptosis.1 It induces ferroptosis, but not apoptosis or necroptosis, in NB1 cancer cells when used at a concentration of 3 μM.1 Chlorido[N,N... | |||
T36227 | Beauveriolide III | ||
Beauveriolide III is a cyclodepsipeptide that has been found inBeauveriaand an inhibitor of lipid droplet formation.1It inhibits lipid droplet formation when used at concentrations of 3 and 10 μM, as well as inhibits cho... | |||
T35821 | CAY10721 | ||
CAY10721 is an inhibitor of sirtuin 3 (SIRT3), a class III HDAC (39% SIRT3 inhibition at 200 μM). Upregulation of SIRT3 transcription is associated with oral squamous cell carcinoma (OSCC) and breast cancer with lymph no... | |||
T35966 | Mn(III)TMPyP | ||
Mn(III)TMPyP is a manganese-porphyrin which acts as a superoxide dismutase (SOD) mimetic and peroxynitrite decomposition catalyst. SOD mimetics described to date are unstable and are capable of catalyzing undesired side-... | |||
T83471 | 10-Deacetyl-13-oxobaccatin III | ||
10-Deacetyl-13-oxobaccatin III, a taxane isolated from Taxus sumatrana, exhibits cytotoxicity at a concentration of 30 μg/mL, inhibiting A498, NCI-H226, A549, and PC-3 cancer cell lines with respective rates of 29.7%, 49... | |||
T37498 | Antimycin A4 | ||
Antimycin A4 is an active component of the antimycin A antibiotic complex that is more polar than antimycin A1 , antimycin A2 , and antimycin A3 . Antimycin A4 inhibits ATP-citrate lyase with a Ki value of 64.8 μM. The a... | |||
T83435 | 19-Hydroxy-10-deacetylbaccatin III | ||
19-Hydroxy-10-deacetylbaccatin III (compound 13), a taxane potentially active against tumors, exhibits low cytotoxicity towards A498 and NCI-H226 cell lines. At a concentration of 30 μg/mL, it inhibits A498 and NCI-H226 ... | |||
T83663 | Mn(III) Protoporphyrin IX Chloride | Manganese(III) Protoporphyrin IX Chloride | |
Mn(III) protoporphyrin IX chloride is a metalloporphyrin that, at a concentration of 10 µM, promotes mRNA expression of δ-aminolevulinate synthase and heme oxygenase (HO) in chick embryo liver cells, enzymes crucial for ... | |||
T62123 | FNDR-20123 | ||
FNDR-20123 is the first safe and effective anti-malarial HDAC inhibitor, acting on both Plasmodium falciparum HDAC (IC50: 31 nM) and human HDAC (IC50: 3 nM). FNDR-20123 inhibited HDAC1 (IC50: 25 nM), HDAC2 (IC50: 29 nM),... | |||
T35822 | CAY10722 | ||
CAY10722 is an inhibitor of sirtuin 3 (SIRT3), a class III HDAC (71% inhibition at 200 μM). SIRT3 is involved in modulating metabolic homeostasis as a NAD+-dependent protein deacetylase in the mitochondria. SIRT3 functio... | |||
T68297 | Dilmapimod tosylate | ||
Dilmapimod tosylate is a potent p38 mitogen-activated protein kinase (MAPK) inhibitor. It was investigated for its anti-inflammatory effect in non-head injury trauma patients at risk for developing acute respiratory dist... | |||
T75540 | Ipomoeassin F | ||
Ipomoeassin F, a selective and potent inhibitor of endoplasmic reticulum (ER) protein translocation, targets the Sec61 complex's pore-forming subunit (Sec61α) at the ER membrane. It inhibits the ER membrane translocation... | |||
T35428 | β-Rubromycin | ||
β-Rubromycin is a bacterial metabolite originally isolated from Streptomyces that has diverse biological activities.1 It inhibits the growth of HMO2, KATO-III, and MCF-7 cells with GI50 values of 0.5, 0.84, and <0.1 μM, ... | |||
T37127 | L-AP4 monohydrate | L-AP4 monohydrate | |
L-AP4 (L-APB) monohydrate is a potent and specific agonist for the group III mGluRs, with EC50s of 0.13, 0.29, 1.0, 249 μM for mGlu4, mGlu8, mGlu6 and mGlu7 receptors, respectively[1][2]. L-AP4 (5-30 μg, intrathecal inhe... | |||
T71401 | Oxaliplatin-d10 | ||
Oxaliplatin-d10 is intended for use as an internal standard for the quantification of oxaliplatin by GC- or LC-MS. Oxaliplatin is a platinum-containing DNA-crosslinking agent. It induces the formation of DNA inter- and i... |