ampk — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T60675L	AMPK activator 2 hydrochloride( 2410961-69-0 Free base)	AMPK activator 2 hydrochloride( 2410961-69-0 Free base)	AMPK
	AMPK activator 2 hydrochloride is a fluoroguanidine-containing derivative that up-regulates the AMPK signaling pathway and down-regulates mTOR/4EBP1/p70S6K.AMPK activator 2 hydrochloride inhibits the proliferation and mi...		AMPK
T78791	AMPK activator 12		AMPK
	AMPK activator 12 is an AMPK activator and GDF15 inducer that elevates the expression level of GDF15 protein in human hepatocytes, which can be used for cancer research.		AMPK
T62745	AMPK-IN-3		VEGFR , AMPK
	AMPK-IN-3 is a novel, selective and potent AMPK inhibitor with inhibitory effects on AMPK (α2), AMPK (α1) and KDR, with IC50 values of 60.7, 107 and 3820 nM, respectively.AMPK-IN-3 showed anticancer activity in K562 cell...		VEGFR , AMPK
T62238	AMPK activator 4		AMPK
	AMPK activator 4 is a potent and selective AMPK activator that does not inhibit mitochondrial complex I. AMPK activator 4 selectively activates AMPK in muscle tissue and dose-dependently improves glucose tolerance in nor...		AMPK
T22567	AMPK activator		Others
	AMPK activator		Others
T70862	AMPK Activator SC4
	SC4 is a potent, direct AMPK activator. SC4 preferentially activates α2 complexes and stimulates skeletal muscle glucose uptake.
T23734	AMPK activator C2	Compound 2,Compound-2,C2
	AMPK activator C2 is an AMPK allosteric activator.
T10069	AMPK activator 1		Others
	AMPK activator 1 is an AMPK activator(compound No.1-75, EC50: <0.1μM).		Others
T72690	AMPK activator 9
	AMPK Activator 9 (ZM-6), a potent activator of AMPK (α2β1γ1), demonstrates an EC50 of 1.1 µM, indicating its strong efficacy in activating AMPK. This compound holds promise for type 2 diabetes research, highlighting its ...
T63177	AMPK activator 8
	AMPK activator 8 (Compound 2) is an AMP-activated protein kinase (AMPK) activator that acts on rAMPK α1β1γ1 (EC50: 11 nM), rAMPK α2β1γ1 (EC50: 27 nM), rAMPK α1β2γ1 (EC50: 4 nM), rAMPK α2β2 AMPK activator 8 can be used to...
T83127	AMPK activator 13		AMPK
	AMPK Activator 13 is a potent activator of the AMPK pathway, effectively inhibiting mitotic clonal expansion in 3T3-L1 cells and enhancing mitochondrial oxygen consumption rates. This compound is utilized in the study of...		AMPK
T60675	AMPK activator 2		AMPK
	AMPK activator 2 is a chloroformin derivative with potential anticancer activity, which can up-regulate AMPK signaling pathway and down-regulate mTOR/4EBP1/p70S6K, and inhibit proliferation and migration of human cancer ...		AMPK
T73224	AMPK-IN-1
	AMPK-IN-1 is an activator of the AMP-activated protein kinase (AMPK) enzyme, specifically targeting the α2β2γ1 isoform with an EC50 of 551 nM. It induces phosphorylation of eEF2 independent of the mTORC1 pathway.
T62052	AMPK activator 6
	AMPK activator 6 (Compound GC) activates the AMPK pathway and reduces lipid content in HepG2 and 3T3-L1 cells. AMPK activator 6 significantly suppresses the increase of total cholesterol (TC), low-density lipoprotein-C (...
T79226	AMPK activator 11		Mitochondrial Metabolism
	AMPK Activator 11 is a nanomolar potent inhibitor of cell proliferation in various colorectal carcinomas (CRCs), acting through the selective activation of AMP-activated protein kinase (AMPK) and enhancement of oxidative...		Mitochondrial Metabolism
T63117	AMPK activator 7
	AMPK activator 7 (compound I-3-24) is an AMPK activator (EC50: 8.8 nM). AMPK activator 7 can be used in studies involving AMPK disorders, particularly type 2 diabetes, hyperglycaemia, metabolic syndrome, obesity, hyperch...
T83125	AMPK-α1β1γ1 activator 1		AMPK
	AMPK-α1β1γ1 activator 1 (M1), an acyl glucuronide metabolite derived from an Indole-3-carboxylic Acid-based AMPK activator, selectively activates the β1 isoforms of human AMPK with an EC50 of 38.1 nM through direct bindi...		AMPK
T79649	CB1R/AMPK modulator 1		Cannabinoid Receptor
	Compound 38-S is an orally active CB1R/AMPK modulator with a K i of 0.81 nM and an IC50 of 3.9 nM for CB1R. This compound activates AMPK and has been shown to decrease food intake and body weight, in addition to enhancin...		Cannabinoid Receptor
TN1828	Kahweol		Apoptosis , NF-κB , AMPK
	Kahweol has anticarcinogenic, anti-angiogenic,and anti-inflammatory activities, it can block the LPS-induced activation of NF-kappaB by preventing IkappaB degradation and inhibiting IkappaB kinase activity.		Apoptosis , NF-κB , AMPK
TN1836	Kudinoside D		LDL , AMPK , PPAR
	Kudinoside D exerts anti-adipogenic effects through modulation of adipogenic transcription factors via AMPK signaling pathway.		LDL , AMPK , PPAR