5α-reductase — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T10636	5α-reductase-IN-1		Others
	5α-reductase-IN-1 is a potent inhibitor of the enzyme 5α-reductase. This compound is primarily employed in research studies to investigate its potential efficacy in treating patterned alopecia. It is commonly used in com...		Others
TN2601	12-O-Methylcarnosic acid		Reductase
	12-O-Methylcarnosic acid is a diterpene carnosic acid isolated from Salvia microphylla, is an active constituent of 5α-Reductase inhibition with an IC50 value of 61.7 μM. 12-O-Methylcarnosic acid has Antioxidant activity...		Reductase
T0488	Finasteride	MK-906	Reductase
	Finasteride (MK-906) is an oral inhibitor of active testosterone 5-alpha-reductase and Ki value is 10 nM.		Reductase
T3378	Alpha-Estradiol	Alfatradiol,17α-Estradiol,Epiestrol,Epiestradiol	Estrogen/progestogen Receptor , Reductase , Endogenous Metabolite
	Alpha-Estradiol (Epiestradiol) is an estrogen that inhibits 5alpha-reductase and has potential in the study of androgenetic alopecia.
T15239	Epristeride	SKF105657,ONO-9302	Others
	Epristeride is a novel inhibor of 5α-reductase.		Others
T71703	Turosteride		Reductase
	Turosteride is a small molecule steroidal 5α-reductase (5α-reductase) inhibitor.Turosteride has antitumor activity for the treatment of oncologic diseases and genitourinary disorders, and may be used in the study of pros...		Reductase
T27798	Lapisteride	CS891B,CS-891,CS-891B,CS891	Others
	Lapisteride (CS-891) a steroidal 5α-reductase inhibitor is used to treat benign prostatic hyperplasia (BPH) and androgenetic alopecia and may be effective in preventing or treating AGA .		Others
T3329	4',7-Dimethoxyisoflavone	Dimethoxydaidzein,Daidzein dimethyl ether	Endogenous Metabolite , Antifungal
	4',7-Dimethoxyisoflavone (Daidzein dimethyl ether) , a kind of isoflavonoids, showed inhibitory effects on rat prostate testosterone 5α-reductase.		Endogenous Metabolite , Antifungal
T5S0543	Isocurcumenol		Apoptosis , Estrogen Receptor/ERR , Reductase
	1. Isocurcumenol inhibits 5α-reductase which converts testosterone to dihydrotestosterone (DHT).		Apoptosis , Estrogen Receptor/ERR , Reductase
T67901	SRD5A1-IN-1		Others
	SRD5A1-IN-1 is an inhibitor of steroid 5α-reductase type 1 (SRD5A1, IC50 = 1.44 µM). SRD5A1-IN-1 lowers the production of dihydrotestosterone and shows a significant decrease in the SRD5A1 protein expression.		Others
T1499	Dutasteride	GG 745,Avodart,GI 198745	Apoptosis , Reductase
	Dutasteride (GI 198745) is a 5-alpha-reductase inhibitor that inhibits both type-1 and type2 isoforms of the enzyme and is used to treat benign prostatic hyperplasia.		Apoptosis , Reductase
T27643	Izonsteride	LY-320236,LY320236,UNII-A5E8C36F34	Reductase
	Izonsteride (LY320236) is a selective and potent 5alpha reductase inhibitor with dual action on the type I and type II isoforms of the enzyme.Izonsteride is used in the treatment of oncology and genitourinary disorders, ...		Reductase
T71703L	Isomer-Turosteride	Isomer-Turosteride(Isomer-137099-09-3)	Reductase
	Isomer-Turosteride (Isomer-Turosteride(Isomer-137099-09-3)) is a novel 5 alpha-reductase inhibitor.The antiprostatic effect of Isomer-Turosteride in adult rats is associated with the inhibition of the conversion of T to ...		Reductase
T27889	LY191704	LY 191704,LY-191704
	LY 191704 is a 5α-reductase type 1 inhibitor.
T33414	MK 0434	MK0434,MK434,MK 434,MK-0434,MK-434
	MK 0434 is a steroid 5α-reductase inhibitor and hormone antagonist associated with a significant reduction in DHT.
T28956	TF-505	FR-146687,FK-687,TF 505,FK687
	TF-505, a steroid 5α-reductase inhibitor, is used potentially for the treatment of benign prostatic hyperplasia.
T75674	Pedunculagin
	Pedunculagin, a potent 5α-reductase type 1 inhibitor, effectively inhibits the production of nitric oxide (NO), IL-6, and IL-8 while also decreasing the protein expression of 5α-reductase. Additionally, it exhibits anti-...
T21668	Finasteride acetate
	Finasteride (MK-906) acetate is a potent and competitive 5α-reductase inhibitor, with an IC 50 of 4.2 nM for type II 5α-reductase. The affinity of Finasteride acetate for type II 5α-reductase enzyme was approximately 100...
T2195L	Epiandrosterone Sulfate	Epiandrosterone 16-bromo,Epiandrosterone
	Epiandrosterone sulfate is a steroid hormone with weak androgenic activity. Epiandrosterone is naturally produced by the enzyme 5α-reductase of the adrenal hormone DHEA.
T28280	Oxendolone	Roxenone,Prostetin
	Oxendolone is a steroidal progestin and antiandrogen. Oxendolone binds to the progesterone receptor (Ki = 20 nM) and androgen receptor (AR) (Ki = 320 nM) and acts as a weak but clinically relevant inhibitor of 5α-reducta...