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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T61807 | 5-HT6/7 antagonist 1 | Dopamine Receptor , 5-HT Receptor | |
5-HT6/7 antagonist 1 is a dual 5-HT6/7/2A and D2 receptor antagonist for the study of dementia and Alzheimer's disease. | |||
T3183 | SAX-187 | WAY 181187,WAY181187 | 5-HT Receptor |
SAX-187 (SAX-187) has high-affinity binding at the human 5-HT6 receptor. | |||
T8720 | PRX-07034 hydrochloride | PRX-07034 | 5-HT Receptor |
PRX-07034 hydrochloride is a selective antagonist of 5-HT6 receptor. It has cognition and memory-enhancing properties and potently decreases food intake and body weight in rodents. PRX-07034 hydrochloride is both a poten... | |||
T79325 | 5-HT6 agonist 1 | 5-HT Receptor | |
Compound 19, a 5-HT6 agonist with an affinity (K i : 5 nM), exhibits antidepressant-like effects and enhances cognitive function while also inhibiting platelet aggregation. It demonstrates high metabolic stability [1]. | |||
T30798 | Cerlapirdine | PF05212365,P -05212365,SAM-531,SAM531,PF-05212365,SAM 531,WAY-262,531 | 5-HT Receptor |
Cerlapirdine (PF-05212365) is a selective, potent, full antagonist of the 5-hydroxytryptamine 6 (5-HT6) receptor. Cerlapirdine is already in clinical development for the treatment of cognitive disorders related to Alzhei... | |||
T61837 | 5-HT6/5-HT2AR antagonist-1 | ||
5-HT6/5-HT2AR antagonist-1 is a powerful and effective compound that acts as a dual antagonist for both the 5-HT6 and 5-HT2A receptors. It exhibits high potency with K i values of 11 nM and 39 nM for the respective recep... | |||
T61207 | 5-HT6/5-HT2A receptor ligand-1 | ||
5-HT6/5-HT2A receptor ligand-1 (compound 33) is a dual antagonist for the 5-HT6 and 5-HT2A receptors. It exhibits a K i value of 2 nM and 11 nM for the respective receptors. This compound holds promise for research in ne... | |||
T61220 | 5-HT6/5-HT2A receptor ligand-2 | ||
Compound 42, a 5-HT6/5-HT2A receptor ligand-2, serves as a dual antagonist for the 5-HT6 and 5-HT2A receptors with Ki values of 25 nM and 32 nM, respectively. This brain-penetrant compound exhibits pro-cognitive properti... | |||
T13007 | ST1936 oxalate | 5-HT Receptor | |
ST1936 oxalate is a selective, nanomolar affinity agonist of 5-HT6 receptor(Ki values of 13 nM, 168 nM and 245 nM for human 5-HT6, 5-HT7 and 5-HT2B receptors, respectively). | |||
T1774 | Intepirdine | RVT-101,SB 742457,GSK-742457 | 5-HT Receptor |
Intepirdine (GSK-742457) is a highly selective 5-HT6 receptor antagonist, used in trials studying the treatment of Alzheimer's Disease. | |||
T10053 | 5HT6-ligand-1 | 5-HT Receptor | |
5HT6-ligand-1 is an orally active ligand of 5-HT6 receptor (Ki = 1.43 nM). | |||
T7103 | Idalopirdine | Lu AE58054 | 5-HT Receptor |
Idalopirdine (Lu AE58054), a selective 5-HT6 receptor antagonist( Ki : 0.83 nM),as a treatment for Alzheimer's disease. | |||
T11948 | Masupirdine free base | Masupirdine,SUVN-502 free base | 5-HT Receptor |
Masupirdine free base (SUVN-502 free base) is an orally available 5-HT6 receptor antagonist that crosses the blood-brain barrier and has a Ki value of 2.04 nM for the human 5-HT6 receptor.Masupirdine free base is potent ... | |||
T4118 | SB 271046 hydrochloride | SB 271046A | 5-HT Receptor |
SB 271046 hydrochloride (SB 271046A) is selective, orally active 5-HT6 antagonist (pKi values are 9.02-8.92, 6.35, 6.55, 6.27 at 5-HT6, 5-HT1A, 5-HT1D and D3, and 6.05, 5.95, 5.76, 5.73, 5.62, 5.55, 5.41, 5.39, 5.27 and ... | |||
T11949 | Masupirdine mesylate | SUVN-502 mesylate,SVN-502 mesylate | 5-HT Receptor |
Masupirdine mesylate (SUVN-502 mesylate) is a selective 5-HT6 receptor antagonist that crosses the blood-brain barrier.Masupirdine mesylate is used in the study of neurological disorders such as Alzheimer's disease and d... | |||
T23396 | ST1936 | ST 1936 oxalate | 5-HT Receptor |
ST1936 (ST 1936 oxalate) is a selective and highly potent 5-HT6 receptor agonist that inhibits human 5-HT6, 5-HT7 and 5-HT2B receptors by fully activating cloned human 5-HT6 receptors. body to stimulate cAMP, Ca2+, ERK1/... | |||
T21499 | Dimebolin | Latrepirdine,Dimebon,Dimebone | 5-HT Receptor |
Dimebolin (Latrepirdine) is a 5-HT6 antagonist. | |||
T26085 | Rilapine | Rilapinum | |
Rilapine is an atypical antipsychotic with high affinity for the 5-HT6 receptor. | |||
T23318L | SB 258585 | 5-HT Receptor | |
SB 258585 is a selective 5-HT6 receptor antagonist.SB 258585 has a high affinity for individual receptor populations in cell lines with human recombinant 5-HT6 receptors.SB 258585 can be used to label both recombinant an... | |||
T11183 | EMDT | 5-HT Receptor | |
EMDT oxalate is a selective 5-HT6 agonist, and has antidepressant effects. |