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Search Results for " 5-ht6 "

20

Compounds

Cat No. Product Name Synonyms Targets
T61807 5-HT6/7 antagonist 1 Dopamine Receptor , 5-HT Receptor
5-HT6/7 antagonist 1 is a dual 5-HT6/7/2A and D2 receptor antagonist for the study of dementia and Alzheimer's disease.
T3183 SAX-187 WAY 181187,WAY181187 5-HT Receptor
SAX-187 (SAX-187) has high-affinity binding at the human 5-HT6 receptor.
T8720 PRX-07034 hydrochloride PRX-07034 5-HT Receptor
PRX-07034 hydrochloride is a selective antagonist of 5-HT6 receptor. It has cognition and memory-enhancing properties and potently decreases food intake and body weight in rodents. PRX-07034 hydrochloride is both a poten...
T79325 5-HT6 agonist 1 5-HT Receptor
Compound 19, a 5-HT6 agonist with an affinity (K i : 5 nM), exhibits antidepressant-like effects and enhances cognitive function while also inhibiting platelet aggregation. It demonstrates high metabolic stability [1].
T30798 Cerlapirdine PF05212365,P -05212365,SAM-531,SAM531,PF-05212365,SAM 531,WAY-262,531 5-HT Receptor
Cerlapirdine (PF-05212365) is a selective, potent, full antagonist of the 5-hydroxytryptamine 6 (5-HT6) receptor. Cerlapirdine is already in clinical development for the treatment of cognitive disorders related to Alzhei...
T61837 5-HT6/5-HT2AR antagonist-1
5-HT6/5-HT2AR antagonist-1 is a powerful and effective compound that acts as a dual antagonist for both the 5-HT6 and 5-HT2A receptors. It exhibits high potency with K i values of 11 nM and 39 nM for the respective recep...
T61207 5-HT6/5-HT2A receptor ligand-1
5-HT6/5-HT2A receptor ligand-1 (compound 33) is a dual antagonist for the 5-HT6 and 5-HT2A receptors. It exhibits a K i value of 2 nM and 11 nM for the respective receptors. This compound holds promise for research in ne...
T61220 5-HT6/5-HT2A receptor ligand-2
Compound 42, a 5-HT6/5-HT2A receptor ligand-2, serves as a dual antagonist for the 5-HT6 and 5-HT2A receptors with Ki values of 25 nM and 32 nM, respectively. This brain-penetrant compound exhibits pro-cognitive properti...
T13007 ST1936 oxalate 5-HT Receptor
ST1936 oxalate is a selective, nanomolar affinity agonist of 5-HT6 receptor(Ki values of 13 nM, 168 nM and 245 nM for human 5-HT6, 5-HT7 and 5-HT2B receptors, respectively).
T1774 Intepirdine RVT-101,SB 742457,GSK-742457 5-HT Receptor
Intepirdine (GSK-742457) is a highly selective 5-HT6 receptor antagonist, used in trials studying the treatment of Alzheimer's Disease.
T10053 5HT6-ligand-1 5-HT Receptor
5HT6-ligand-1 is an orally active ligand of 5-HT6 receptor (Ki = 1.43 nM).
T7103 Idalopirdine Lu AE58054 5-HT Receptor
Idalopirdine (Lu AE58054), a selective 5-HT6 receptor antagonist( Ki : 0.83 nM),as a treatment for Alzheimer's disease.
T11948 Masupirdine free base Masupirdine,SUVN-502 free base 5-HT Receptor
Masupirdine free base (SUVN-502 free base) is an orally available 5-HT6 receptor antagonist that crosses the blood-brain barrier and has a Ki value of 2.04 nM for the human 5-HT6 receptor.Masupirdine free base is potent ...
T4118 SB 271046 hydrochloride SB 271046A 5-HT Receptor
SB 271046 hydrochloride (SB 271046A) is selective, orally active 5-HT6 antagonist (pKi values are 9.02-8.92, 6.35, 6.55, 6.27 at 5-HT6, 5-HT1A, 5-HT1D and D3, and 6.05, 5.95, 5.76, 5.73, 5.62, 5.55, 5.41, 5.39, 5.27 and ...
T11949 Masupirdine mesylate SUVN-502 mesylate,SVN-502 mesylate 5-HT Receptor
Masupirdine mesylate (SUVN-502 mesylate) is a selective 5-HT6 receptor antagonist that crosses the blood-brain barrier.Masupirdine mesylate is used in the study of neurological disorders such as Alzheimer's disease and d...
T23396 ST1936 ST 1936 oxalate 5-HT Receptor
ST1936 (ST 1936 oxalate) is a selective and highly potent 5-HT6 receptor agonist that inhibits human 5-HT6, 5-HT7 and 5-HT2B receptors by fully activating cloned human 5-HT6 receptors. body to stimulate cAMP, Ca2+, ERK1/...
T21499 Dimebolin Latrepirdine,Dimebon,Dimebone 5-HT Receptor
Dimebolin (Latrepirdine) is a 5-HT6 antagonist.
T26085 Rilapine Rilapinum
Rilapine is an atypical antipsychotic with high affinity for the 5-HT6 receptor.
T23318L SB 258585 5-HT Receptor
SB 258585 is a selective 5-HT6 receptor antagonist.SB 258585 has a high affinity for individual receptor populations in cell lines with human recombinant 5-HT6 receptors.SB 258585 can be used to label both recombinant an...
T11183 EMDT 5-HT Receptor
EMDT oxalate is a selective 5-HT6 agonist, and has antidepressant effects.
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