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Chemokines

Chemokines are a family of small cytokines or signaling proteins secreted by cells that induce directional movement of leukocytes, as well as other cell types, including endothelial and epithelial cells. In addition to playing a major role in the activation of host immune responses, chemokines are important for biological processes, including morphogenesis and wound healing, as well as in the pathogenesis of diseases like cancers. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controlling the migration of cells during normal processes of tissue maintenance or development. Chemokines have been classified into four main subfamilies: CXC, CC, CX3C and C. All of these proteins exert their biological effects by interacting with G protein-linked transmembrane receptors called chemokine receptors.

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Species
Canine (9)
Cynomolgus (10)
Human (87)
Mouse (45)
Rat (12)
Rhesus (8)
Expression System
Baculovirus Insect Cells (21)
E. coli (75)
HEK293 Cells (54)
P. pastoris (Yeast) (18)
Tag
C-6xHis (10)
C-His (45)
C-His-Avi (3)
C-Mucin-His (1)
C-hFc (9)
C-hFc-6xHis (2)
C-mFc (1)
His (4)
N-6xHis (3)
N-His (22)
N-His-Avi (3)
N-His-Sumo (1)
N-SUMO (1)
N-hFc (12)
N-mFc (1)
NusA (2)
SUMO (2)
Tag Free (50)
Cat No. product name / Synonyms Species Expression System
TMPJ-01000 CCL9 Protein, Mouse, Recombinant
CCL9 Protein, Mouse, Recombinant
Mouse E. coli
C-C motif chemokine 9(CCL9) is an 11 kDa, secreted, monomeric polypeptide that belongs to the beta (or CC) intercrine family of chemokines. It is expressed mainl...
TMPJ-01001 CCL11 Protein, Human, Recombinant
CCL11 Protein, Human, Recombinant
Human E. coli
C-C Motif Chemokine 11 (CCL11) is a secreted protein that belongs to the intercrine beta (chemokine CC) family. In response to the presence of allergens, CCL11 s...
TMPJ-01060 CXCL6 Protein, Human, Recombinant (His)
CXCL6 Protein, Human, Recombinant (His)
Human HEK293 Cells
Chemokine (C-X-C-Motif) Ligand 6 (CXCL6) is a small cytokine belonging to the CXC chemokine family. It is a potent neutrophil chemotactic and activating factor a...
TMPJ-01084 CXCL9 Protein, Human, Recombinant (His)
CXCL9 Protein, Human, Recombinant (His)
Human HEK293 Cells
Chemokine (C-X-C Motif) Ligand 9 (CXCL9) belongs to the intercrine alpha (chemokine CXC) family. It is secreted by interferon stimulated monocytes, macrophages a...
TMPJ-01279 TAFA4 Protein, Human, Recombinant (His)
TAFA4 Protein, Human, Recombinant (His)
Human E. coli
FAM19A4 is a secreted, 12 kDa member of the FAM19/TAFA family of chemokine-like proteins. Like other members of the FAM19/TAFA family, with the exception of TAFA...
TMPJ-01341 CCL24 Protein, Mouse, Recombinant
CCL24 Protein, Mouse, Recombinant
Mouse E. coli
Mouse CCL24 is a secreted protein, which is a member of the CC chemokine subfamily. Mouse Ccl24 cDNA encodes a 119 amino acid residue precursor protein, shares a...
TMPJ-01394 CXCL15 Protein, Mouse, Recombinant (His)
CXCL15 Protein, Mouse, Recombinant (His)
Mouse HEK293 Cells
Mouse C-X-C motif chemokine 15, also known as Cxcl15, is a secreted protein which is member of the ELR motif-containing CXC chemokines. It expressed at low level...
TMPJ-01409 CCL27 Protein, Human, Recombinant
CCL27 Protein, Human, Recombinant
Human E. coli
Human Chemokine (C-C Motif) Ligand 27 (CCL27) is a small cytokine that is a member of the CC chemokine family; it is expressed in numerous tissues, including gon...
TMPK-00008 CCL5 Protein, Mouse, Recombinant (hFc)
CCL5 Protein, Mouse, Recombinant (hFc)
Mouse HEK293 Cells
The CCR5 and the CCL5 ligand have been detected in some hematological malignancies, lymphomas, and a great number of solid tumors, but extensive studies on the r...
TMPK-00009 CCL5 Protein, Human, Recombinant (His & Avi), Biotinylated
CCL5 Protein, Human, Recombinant (His & Avi), Biotinylated
Human E. coli
The CCR5 and the CCL5 ligand have been detected in some hematological malignancies, lymphomas, and a great number of solid tumors, but extensive studies on the r...
TMPK-00010 MCP-1/CCL2 Protein, Human, Recombinant (His & Avi)
MCP-1/CCL2 Protein, Human, Recombinant (His & Avi)
Human HEK293 Cells
MCP-1/CCL2 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 11.5 kDa and the ...
TMPK-00011 MCP-1/CCL2 Protein, Human, Recombinant (His & Avi), Biotinylated
MCP-1/CCL2 Protein, Human, Recombinant (His & Avi), Biotinylated
Human HEK293 Cells
MCP-1/CCL2 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 11....
TMPK-00012 CXCL4 Protein, Human, Recombinant (His & Avi)
CXCL4 Protein, Human, Recombinant (His & Avi)
Human E. coli
Chemokines regulate leukocyte migration during physiological and pathological conditions. It is currently accepted that these chemotactic cytokines are also impo...
TMPK-00013 CXCL4 Protein, Human, Recombinant (His & Avi), Biotinylated
CXCL4 Protein, Human, Recombinant (His & Avi), Biotinylated
Human E. coli
Chemokines regulate leukocyte migration during physiological and pathological conditions. It is currently accepted that these chemotactic cytokines are also impo...
TMPK-00014 CXCL4 Protein, Human, Recombinant (hFc)
CXCL4 Protein, Human, Recombinant (hFc)
Human HEK293 Cells
Chemokines regulate leukocyte migration during physiological and pathological conditions. It is currently accepted that these chemotactic cytokines are also impo...
TMPK-00017 CXCL13/BCA-1 Protein, Human, Recombinant (hFc)
CXCL13/BCA-1 Protein, Human, Recombinant (hFc)
Human HEK293 Cells
Recent studies have implicated chemokines in microglial activation and pathogenesis of neuropathic pain. C-X-C motif chemokine 13 (CXCL13) is a B lymphocyte chem...
TMPK-00018 CXCL13/BCA-1 Protein, Human, Recombinant (His & Sumo)
CXCL13/BCA-1 Protein, Human, Recombinant (His & Sumo)
Human E. coli
Recent studies have implicated chemokines in microglial activation and pathogenesis of neuropathic pain. C-X-C motif chemokine 13 (CXCL13) is a B lymphocyte chem...
TMPK-00138 CXCL16 Protein, Mouse, Recombinant (hFc)
CXCL16 Protein, Mouse, Recombinant (hFc)
Mouse HEK293 Cells
CXC chemokine ligand 16 (CXCL16) is a CXC soluble chemokine, an adhesion molecule and a cell surface scavenger receptor. CXCL16 regulates inflammation, tissue in...
TMPK-00469 CXCL16 Protein, Human, Recombinant (hFc)
CXCL16 Protein, Human, Recombinant (hFc)
Human HEK293 Cells
CXC chemokine ligand 16 (CXCL16) is a CXC soluble chemokine, an adhesion molecule and a cell surface scavenger receptor. CXCL16 regulates inflammation, tissue in...
TMPK-00480 IL-8/CXCL8 Protein, Cynomolgus, Recombinant (His)
IL-8/CXCL8 Protein, Cynomolgus, Recombinant (His)
Cynomolgus HEK293 Cells
Interleukin-8 (IL-8) has been revealed as a critical regulator of CNS function and development with participation in many CNS disorders including gliomas.Several...
CCL9 Protein, Mouse, Recombinant
TMPJ-01000
C-C motif chemokine 9(CCL9) is an 11 kDa, secreted, monomeric polypeptide that belongs to the beta (or CC) intercrine family of chemokines. It is expressed mainl...
CCL11 Protein, Human, Recombinant
TMPJ-01001
C-C Motif Chemokine 11 (CCL11) is a secreted protein that belongs to the intercrine beta (chemokine CC) family. In response to the presence of allergens, CCL11 s...
CXCL6 Protein, Human, Recombinant (His)
TMPJ-01060
Chemokine (C-X-C-Motif) Ligand 6 (CXCL6) is a small cytokine belonging to the CXC chemokine family. It is a potent neutrophil chemotactic and activating factor a...
CXCL9 Protein, Human, Recombinant (His)
TMPJ-01084
Chemokine (C-X-C Motif) Ligand 9 (CXCL9) belongs to the intercrine alpha (chemokine CXC) family. It is secreted by interferon stimulated monocytes, macrophages a...
TAFA4 Protein, Human, Recombinant (His)
TMPJ-01279
FAM19A4 is a secreted, 12 kDa member of the FAM19/TAFA family of chemokine-like proteins. Like other members of the FAM19/TAFA family, with the exception of TAFA...
CCL24 Protein, Mouse, Recombinant
TMPJ-01341
Mouse CCL24 is a secreted protein, which is a member of the CC chemokine subfamily. Mouse Ccl24 cDNA encodes a 119 amino acid residue precursor protein, shares a...
CXCL15 Protein, Mouse, Recombinant (His)
TMPJ-01394
Mouse C-X-C motif chemokine 15, also known as Cxcl15, is a secreted protein which is member of the ELR motif-containing CXC chemokines. It expressed at low level...
CCL27 Protein, Human, Recombinant
TMPJ-01409
Human Chemokine (C-C Motif) Ligand 27 (CCL27) is a small cytokine that is a member of the CC chemokine family; it is expressed in numerous tissues, including gon...
CCL5 Protein, Mouse, Recombinant (hFc)
TMPK-00008
The CCR5 and the CCL5 ligand have been detected in some hematological malignancies, lymphomas, and a great number of solid tumors, but extensive studies on the r...
CCL5 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00009
The CCR5 and the CCL5 ligand have been detected in some hematological malignancies, lymphomas, and a great number of solid tumors, but extensive studies on the r...
MCP-1/CCL2 Protein, Human, Recombinant (His & Avi)
TMPK-00010
MCP-1/CCL2 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 11.5 kDa and the ...
MCP-1/CCL2 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00011
MCP-1/CCL2 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 11....
CXCL4 Protein, Human, Recombinant (His & Avi)
TMPK-00012
Chemokines regulate leukocyte migration during physiological and pathological conditions. It is currently accepted that these chemotactic cytokines are also impo...
CXCL4 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00013
Chemokines regulate leukocyte migration during physiological and pathological conditions. It is currently accepted that these chemotactic cytokines are also impo...
CXCL4 Protein, Human, Recombinant (hFc)
TMPK-00014
Chemokines regulate leukocyte migration during physiological and pathological conditions. It is currently accepted that these chemotactic cytokines are also impo...
CXCL13/BCA-1 Protein, Human, Recombinant (hFc)
TMPK-00017
Recent studies have implicated chemokines in microglial activation and pathogenesis of neuropathic pain. C-X-C motif chemokine 13 (CXCL13) is a B lymphocyte chem...
CXCL13/BCA-1 Protein, Human, Recombinant (His & Sumo)
TMPK-00018
Recent studies have implicated chemokines in microglial activation and pathogenesis of neuropathic pain. C-X-C motif chemokine 13 (CXCL13) is a B lymphocyte chem...
CXCL16 Protein, Mouse, Recombinant (hFc)
TMPK-00138
CXC chemokine ligand 16 (CXCL16) is a CXC soluble chemokine, an adhesion molecule and a cell surface scavenger receptor. CXCL16 regulates inflammation, tissue in...
CXCL16 Protein, Human, Recombinant (hFc)
TMPK-00469
CXC chemokine ligand 16 (CXCL16) is a CXC soluble chemokine, an adhesion molecule and a cell surface scavenger receptor. CXCL16 regulates inflammation, tissue in...
IL-8/CXCL8 Protein, Cynomolgus, Recombinant (His)
TMPK-00480
Interleukin-8 (IL-8) has been revealed as a critical regulator of CNS function and development with participation in many CNS disorders including gliomas.Several...
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TargetMol