Chemokines are a family of small cytokines or signaling proteins secreted by cells that induce directional movement of leukocytes, as well as other cell types, including endothelial and epithelial cells. In addition to playing a major role in the activation of host immune responses, chemokines are important for biological processes, including morphogenesis and wound healing, as well as in the pathogenesis of diseases like cancers. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controlling the migration of cells during normal processes of tissue maintenance or development. Chemokines have been classified into four main subfamilies: CXC, CC, CX3C and C. All of these proteins exert their biological effects by interacting with G protein-linked transmembrane receptors called chemokine receptors.
Cat No. | product name / Synonyms | Species | Expression System |
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TMPJ-01000 | CCL9 Protein, Mouse, Recombinant
CCL9 Protein, Mouse, Recombinant
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Mouse | E. coli |
C-C motif chemokine 9(CCL9) is an 11 kDa, secreted, monomeric polypeptide that belongs to the beta (or CC) intercrine family of chemokines. It is expressed mainl... | |||
TMPJ-01001 | CCL11 Protein, Human, Recombinant
CCL11 Protein, Human, Recombinant
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Human | E. coli |
C-C Motif Chemokine 11 (CCL11) is a secreted protein that belongs to the intercrine beta (chemokine CC) family. In response to the presence of allergens, CCL11 s... | |||
TMPJ-01060 | CXCL6 Protein, Human, Recombinant (His)
CXCL6 Protein, Human, Recombinant (His)
|
Human | HEK293 Cells |
Chemokine (C-X-C-Motif) Ligand 6 (CXCL6) is a small cytokine belonging to the CXC chemokine family. It is a potent neutrophil chemotactic and activating factor a... | |||
TMPJ-01084 | CXCL9 Protein, Human, Recombinant (His)
CXCL9 Protein, Human, Recombinant (His)
|
Human | HEK293 Cells |
Chemokine (C-X-C Motif) Ligand 9 (CXCL9) belongs to the intercrine alpha (chemokine CXC) family. It is secreted by interferon stimulated monocytes, macrophages a... | |||
TMPJ-01279 | TAFA4 Protein, Human, Recombinant (His)
TAFA4 Protein, Human, Recombinant (His)
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Human | E. coli |
FAM19A4 is a secreted, 12 kDa member of the FAM19/TAFA family of chemokine-like proteins. Like other members of the FAM19/TAFA family, with the exception of TAFA... | |||
TMPJ-01341 | CCL24 Protein, Mouse, Recombinant
CCL24 Protein, Mouse, Recombinant
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Mouse | E. coli |
Mouse CCL24 is a secreted protein, which is a member of the CC chemokine subfamily. Mouse Ccl24 cDNA encodes a 119 amino acid residue precursor protein, shares a... | |||
TMPJ-01394 | CXCL15 Protein, Mouse, Recombinant (His)
CXCL15 Protein, Mouse, Recombinant (His)
|
Mouse | HEK293 Cells |
Mouse C-X-C motif chemokine 15, also known as Cxcl15, is a secreted protein which is member of the ELR motif-containing CXC chemokines. It expressed at low level... | |||
TMPJ-01409 | CCL27 Protein, Human, Recombinant
CCL27 Protein, Human, Recombinant
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Human | E. coli |
Human Chemokine (C-C Motif) Ligand 27 (CCL27) is a small cytokine that is a member of the CC chemokine family; it is expressed in numerous tissues, including gon... | |||
TMPK-00008 | CCL5 Protein, Mouse, Recombinant (hFc)
CCL5 Protein, Mouse, Recombinant (hFc)
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Mouse | HEK293 Cells |
The CCR5 and the CCL5 ligand have been detected in some hematological malignancies, lymphomas, and a great number of solid tumors, but extensive studies on the r... | |||
TMPK-00009 | CCL5 Protein, Human, Recombinant (His & Avi), Biotinylated
CCL5 Protein, Human, Recombinant (His & Avi), Biotinylated
|
Human | E. coli |
The CCR5 and the CCL5 ligand have been detected in some hematological malignancies, lymphomas, and a great number of solid tumors, but extensive studies on the r... | |||
TMPK-00010 | MCP-1/CCL2 Protein, Human, Recombinant (His & Avi)
MCP-1/CCL2 Protein, Human, Recombinant (His & Avi)
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Human | HEK293 Cells |
MCP-1/CCL2 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 11.5 kDa and the ... | |||
TMPK-00011 | MCP-1/CCL2 Protein, Human, Recombinant (His & Avi), Biotinylated
MCP-1/CCL2 Protein, Human, Recombinant (His & Avi), Biotinylated
|
Human | HEK293 Cells |
MCP-1/CCL2 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 11.... | |||
TMPK-00012 | CXCL4 Protein, Human, Recombinant (His & Avi)
CXCL4 Protein, Human, Recombinant (His & Avi)
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Human | E. coli |
Chemokines regulate leukocyte migration during physiological and pathological conditions. It is currently accepted that these chemotactic cytokines are also impo... | |||
TMPK-00013 | CXCL4 Protein, Human, Recombinant (His & Avi), Biotinylated
CXCL4 Protein, Human, Recombinant (His & Avi), Biotinylated
|
Human | E. coli |
Chemokines regulate leukocyte migration during physiological and pathological conditions. It is currently accepted that these chemotactic cytokines are also impo... | |||
TMPK-00014 | CXCL4 Protein, Human, Recombinant (hFc)
CXCL4 Protein, Human, Recombinant (hFc)
|
Human | HEK293 Cells |
Chemokines regulate leukocyte migration during physiological and pathological conditions. It is currently accepted that these chemotactic cytokines are also impo... | |||
TMPK-00017 | CXCL13/BCA-1 Protein, Human, Recombinant (hFc)
CXCL13/BCA-1 Protein, Human, Recombinant (hFc)
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Human | HEK293 Cells |
Recent studies have implicated chemokines in microglial activation and pathogenesis of neuropathic pain. C-X-C motif chemokine 13 (CXCL13) is a B lymphocyte chem... | |||
TMPK-00018 | CXCL13/BCA-1 Protein, Human, Recombinant (His & Sumo)
CXCL13/BCA-1 Protein, Human, Recombinant (His & Sumo)
|
Human | E. coli |
Recent studies have implicated chemokines in microglial activation and pathogenesis of neuropathic pain. C-X-C motif chemokine 13 (CXCL13) is a B lymphocyte chem... | |||
TMPK-00138 | CXCL16 Protein, Mouse, Recombinant (hFc)
CXCL16 Protein, Mouse, Recombinant (hFc)
|
Mouse | HEK293 Cells |
CXC chemokine ligand 16 (CXCL16) is a CXC soluble chemokine, an adhesion molecule and a cell surface scavenger receptor. CXCL16 regulates inflammation, tissue in... | |||
TMPK-00469 | CXCL16 Protein, Human, Recombinant (hFc)
CXCL16 Protein, Human, Recombinant (hFc)
|
Human | HEK293 Cells |
CXC chemokine ligand 16 (CXCL16) is a CXC soluble chemokine, an adhesion molecule and a cell surface scavenger receptor. CXCL16 regulates inflammation, tissue in... | |||
TMPK-00480 | IL-8/CXCL8 Protein, Cynomolgus, Recombinant (His)
IL-8/CXCL8 Protein, Cynomolgus, Recombinant (His)
|
Cynomolgus | HEK293 Cells |
Interleukin-8 (IL-8) has been revealed as a critical regulator of CNS function and development with participation in many CNS disorders including gliomas.Several... |