Chemokines are a family of small cytokines or signaling proteins secreted by cells that induce directional movement of leukocytes, as well as other cell types, including endothelial and epithelial cells. In addition to playing a major role in the activation of host immune responses, chemokines are important for biological processes, including morphogenesis and wound healing, as well as in the pathogenesis of diseases like cancers. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controlling the migration of cells during normal processes of tissue maintenance or development. Chemokines have been classified into four main subfamilies: CXC, CC, CX3C and C. All of these proteins exert their biological effects by interacting with G protein-linked transmembrane receptors called chemokine receptors.
Cat No. | product name / Synonyms | Species | Expression System |
---|---|---|---|
TMPK-00704 | CCL24 Protein, Human, Recombinant (hFc)
CCL24 Protein, Human, Recombinant (hFc)
|
Human | HEK293 Cells |
C-C motif chemokine ligand 24 (CCL24) is a chemokine that regulates inflammatory and fibrotic activities through its receptor, C-C motif chemokine receptor (CCR3... | |||
TMPK-00721 | CX3CL1/Fractalkine Protein, Mouse, Recombinant (His & Avi), Biotinylated
CX3CL1/Fractalkine Protein, Mouse, Recombinant (His & Avi), Biotinylated
|
Mouse | HEK293 Cells |
Fractalkine/CX3C chemokine ligand 1 (CX3CL1) is a chemokine involved in the anticancer function of lymphocytes-mainly NK cells, T cells and dendritic cells. Its ... | |||
TMPK-00734 | CXCL13/BCA-1 Protein, Mouse, Recombinant (hFc)
CXCL13/BCA-1 Protein, Mouse, Recombinant (hFc)
|
Mouse | HEK293 Cells |
Recent studies have implicated chemokines in microglial activation and pathogenesis of neuropathic pain. C-X-C motif chemokine 13 (CXCL13) is a B lymphocyte chem... | |||
TMPK-00735 | CXCL13/BCA-1 Protein, Mouse, Recombinant (His)
CXCL13/BCA-1 Protein, Mouse, Recombinant (His)
|
Mouse | HEK293 Cells |
Recent studies have implicated chemokines in microglial activation and pathogenesis of neuropathic pain. C-X-C motif chemokine 13 (CXCL13) is a B lymphocyte chem... | |||
TMPK-00916 | MCP-1/CCL2 Protein, Cynomolgus, Recombinant (His)
MCP-1/CCL2 Protein, Cynomolgus, Recombinant (His)
|
Cynomolgus | HEK293 Cells |
MCP-1/CCL2 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 9.79 kDa and the acces... | |||
TMPK-01195 | CCL24 Protein, Mouse, Recombinant (hFc)
CCL24 Protein, Mouse, Recombinant (hFc)
|
Mouse | HEK293 Cells |
C-C motif chemokine ligand 24 (CCL24) is a chemokine that regulates inflammatory and fibrotic activities through its receptor, C-C motif chemokine receptor (CCR3... | |||
TMPK-01196 | CCL24 Protein, Mouse, Recombinant (His)
CCL24 Protein, Mouse, Recombinant (His)
|
Mouse | HEK293 Cells |
C-C motif chemokine ligand 24 (CCL24) is a chemokine that regulates inflammatory and fibrotic activities through its receptor, C-C motif chemokine receptor (CCR3... | |||
TMPK-01248 | CXCL4 Protein, Mouse, Recombinant (hFc)
CXCL4 Protein, Mouse, Recombinant (hFc)
|
Mouse | HEK293 Cells |
Chemokines regulate leukocyte migration during physiological and pathological conditions. It is currently accepted that these chemotactic cytokines are also impo... | |||
TMPK-01265 | CCL24 Protein, Cynomolgus, Recombinant (His)
CCL24 Protein, Cynomolgus, Recombinant (His)
|
Cynomolgus | HEK293 Cells |
C-C motif chemokine ligand 24 (CCL24) is a chemokine that regulates inflammatory and fibrotic activities through its receptor, C-C motif chemokine receptor (CCR3... | |||
TMPK-01269 | CXCL10 Protein, Cynomolgus, Recombinant (His)
CXCL10 Protein, Cynomolgus, Recombinant (His)
|
Cynomolgus | E. coli |
C-X-C motif ligand 10 (CXCL10), or interferon-inducible protein-10, is a small chemokine belonging to the CXC chemokine family. Its members are responsible for l... | |||
TMPY-00001 | CXCL14 Protein, Mouse, Recombinant
CXCL14 Protein, Mouse, Recombinant
|
Mouse | E. coli |
CXCL14 Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 9.4 kDa and the accession number is Q9WUQ5. | |||
TMPY-00006 | GRO beta/CXCL2 Protein, Human, Recombinant
GRO beta/CXCL2 Protein, Human, Recombinant
|
Human | E. coli |
GRO beta/CXCL2 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 7.9 kDa and the accession number is A0A02... | |||
TMPY-00008 | CXCL1 Protein, Rat, Recombinant
CXCL1 Protein, Rat, Recombinant
|
Rat | E. coli |
CXCL1 Protein, Rat, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 7.9 kDa and the accession number is P14095. | |||
TMPY-00009 | GRO beta/CXCL2 Protein, Rat, Recombinant
GRO beta/CXCL2 Protein, Rat, Recombinant
|
Rat | E. coli |
GRO beta/CXCL2 Protein, Rat, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 7.6 kDa and the accession number is A6KKD4.... | |||
TMPY-00168 | MPIF-1/CCL23 Protein, Human, Recombinant (His)
MPIF-1/CCL23 Protein, Human, Recombinant (His)
|
Human | P. pastoris (Yeast) |
MPIF-1/CCL23 Protein, Human, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 9.9 kDa and the accession number is P55773.3... | |||
TMPY-00218 | CXCL7 Protein, Mouse, Recombinant (aa 40-113, His)
CXCL7 Protein, Mouse, Recombinant (aa 40-113, His)
|
Mouse | E. coli |
CXCL7 Protein, Mouse, Recombinant (aa 40-113, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 10.4 kDa and the acc... | |||
TMPY-00305 | MDC Protein, Mouse, Recombinant (His)
MDC Protein, Mouse, Recombinant (His)
|
Mouse | E. coli |
MDC Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 9.9 kDa and the accession number ... | |||
TMPY-00433 | CXCL1 Protein, Mouse, Recombinant
CXCL1 Protein, Mouse, Recombinant
|
Mouse | E. coli |
CXCL1 Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 8.3 kDa and the accession number is A2RTH0. | |||
TMPY-00469 | CXCL7 Protein, Human, Recombinant (His)
CXCL7 Protein, Human, Recombinant (His)
|
Human | E. coli |
CXCL7 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 9.9 kDa and the accession numbe... | |||
TMPY-00564 | MCP-4 Protein, Human, Recombinant (His)
MCP-4 Protein, Human, Recombinant (His)
|
Human | P. pastoris (Yeast) |
Monocyte Chemoattractant Proteins 4 (MCP-4/CCL13) is a member of a distinct, structurally-related subclass of CC chemokines mainly involved in recruitment of eos... |