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Chemokines

Chemokines are a family of small cytokines or signaling proteins secreted by cells that induce directional movement of leukocytes, as well as other cell types, including endothelial and epithelial cells. In addition to playing a major role in the activation of host immune responses, chemokines are important for biological processes, including morphogenesis and wound healing, as well as in the pathogenesis of diseases like cancers. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controlling the migration of cells during normal processes of tissue maintenance or development. Chemokines have been classified into four main subfamilies: CXC, CC, CX3C and C. All of these proteins exert their biological effects by interacting with G protein-linked transmembrane receptors called chemokine receptors.

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Species
Canine (9)
Cynomolgus (10)
Human (87)
Mouse (45)
Rat (12)
Rhesus (8)
Expression System
Baculovirus Insect Cells (21)
E. coli (75)
HEK293 Cells (54)
P. pastoris (Yeast) (18)
Tag
C-6xHis (10)
C-His (45)
C-His-Avi (3)
C-Mucin-His (1)
C-hFc (9)
C-hFc-6xHis (2)
C-mFc (1)
His (4)
N-6xHis (3)
N-His (22)
N-His-Avi (3)
N-His-Sumo (1)
N-SUMO (1)
N-hFc (12)
N-mFc (1)
NusA (2)
SUMO (2)
Tag Free (50)
Cat No. product name / Synonyms Species Expression System
TMPK-00704 CCL24 Protein, Human, Recombinant (hFc)
CCL24 Protein, Human, Recombinant (hFc)
Human HEK293 Cells
C-C motif chemokine ligand 24 (CCL24) is a chemokine that regulates inflammatory and fibrotic activities through its receptor, C-C motif chemokine receptor (CCR3...
TMPK-00721 CX3CL1/Fractalkine Protein, Mouse, Recombinant (His & Avi), Biotinylated
CX3CL1/Fractalkine Protein, Mouse, Recombinant (His & Avi), Biotinylated
Mouse HEK293 Cells
Fractalkine/CX3C chemokine ligand 1 (CX3CL1) is a chemokine involved in the anticancer function of lymphocytes-mainly NK cells, T cells and dendritic cells. Its ...
TMPK-00734 CXCL13/BCA-1 Protein, Mouse, Recombinant (hFc)
CXCL13/BCA-1 Protein, Mouse, Recombinant (hFc)
Mouse HEK293 Cells
Recent studies have implicated chemokines in microglial activation and pathogenesis of neuropathic pain. C-X-C motif chemokine 13 (CXCL13) is a B lymphocyte chem...
TMPK-00735 CXCL13/BCA-1 Protein, Mouse, Recombinant (His)
CXCL13/BCA-1 Protein, Mouse, Recombinant (His)
Mouse HEK293 Cells
Recent studies have implicated chemokines in microglial activation and pathogenesis of neuropathic pain. C-X-C motif chemokine 13 (CXCL13) is a B lymphocyte chem...
TMPK-00916 MCP-1/CCL2 Protein, Cynomolgus, Recombinant (His)
MCP-1/CCL2 Protein, Cynomolgus, Recombinant (His)
Cynomolgus HEK293 Cells
MCP-1/CCL2 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 9.79 kDa and the acces...
TMPK-01195 CCL24 Protein, Mouse, Recombinant (hFc)
CCL24 Protein, Mouse, Recombinant (hFc)
Mouse HEK293 Cells
C-C motif chemokine ligand 24 (CCL24) is a chemokine that regulates inflammatory and fibrotic activities through its receptor, C-C motif chemokine receptor (CCR3...
TMPK-01196 CCL24 Protein, Mouse, Recombinant (His)
CCL24 Protein, Mouse, Recombinant (His)
Mouse HEK293 Cells
C-C motif chemokine ligand 24 (CCL24) is a chemokine that regulates inflammatory and fibrotic activities through its receptor, C-C motif chemokine receptor (CCR3...
TMPK-01248 CXCL4 Protein, Mouse, Recombinant (hFc)
CXCL4 Protein, Mouse, Recombinant (hFc)
Mouse HEK293 Cells
Chemokines regulate leukocyte migration during physiological and pathological conditions. It is currently accepted that these chemotactic cytokines are also impo...
TMPK-01265 CCL24 Protein, Cynomolgus, Recombinant (His)
CCL24 Protein, Cynomolgus, Recombinant (His)
Cynomolgus HEK293 Cells
C-C motif chemokine ligand 24 (CCL24) is a chemokine that regulates inflammatory and fibrotic activities through its receptor, C-C motif chemokine receptor (CCR3...
TMPK-01269 CXCL10 Protein, Cynomolgus, Recombinant (His)
CXCL10 Protein, Cynomolgus, Recombinant (His)
Cynomolgus E. coli
C-X-C motif ligand 10 (CXCL10), or interferon-inducible protein-10, is a small chemokine belonging to the CXC chemokine family. Its members are responsible for l...
TMPY-00001 CXCL14 Protein, Mouse, Recombinant
CXCL14 Protein, Mouse, Recombinant
Mouse E. coli
CXCL14 Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 9.4 kDa and the accession number is Q9WUQ5.
TMPY-00006 GRO beta/CXCL2 Protein, Human, Recombinant
GRO beta/CXCL2 Protein, Human, Recombinant
Human E. coli
GRO beta/CXCL2 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 7.9 kDa and the accession number is A0A02...
TMPY-00008 CXCL1 Protein, Rat, Recombinant
CXCL1 Protein, Rat, Recombinant
Rat E. coli
CXCL1 Protein, Rat, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 7.9 kDa and the accession number is P14095.
TMPY-00009 GRO beta/CXCL2 Protein, Rat, Recombinant
GRO beta/CXCL2 Protein, Rat, Recombinant
Rat E. coli
GRO beta/CXCL2 Protein, Rat, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 7.6 kDa and the accession number is A6KKD4....
TMPY-00168 MPIF-1/CCL23 Protein, Human, Recombinant (His)
MPIF-1/CCL23 Protein, Human, Recombinant (His)
Human P. pastoris (Yeast)
MPIF-1/CCL23 Protein, Human, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 9.9 kDa and the accession number is P55773.3...
TMPY-00218 CXCL7 Protein, Mouse, Recombinant (aa 40-113, His)
CXCL7 Protein, Mouse, Recombinant (aa 40-113, His)
Mouse E. coli
CXCL7 Protein, Mouse, Recombinant (aa 40-113, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 10.4 kDa and the acc...
TMPY-00305 MDC Protein, Mouse, Recombinant (His)
MDC Protein, Mouse, Recombinant (His)
Mouse E. coli
MDC Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 9.9 kDa and the accession number ...
TMPY-00433 CXCL1 Protein, Mouse, Recombinant
CXCL1 Protein, Mouse, Recombinant
Mouse E. coli
CXCL1 Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 8.3 kDa and the accession number is A2RTH0.
TMPY-00469 CXCL7 Protein, Human, Recombinant (His)
CXCL7 Protein, Human, Recombinant (His)
Human E. coli
CXCL7 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 9.9 kDa and the accession numbe...
TMPY-00564 MCP-4 Protein, Human, Recombinant (His)
MCP-4 Protein, Human, Recombinant (His)
Human P. pastoris (Yeast)
Monocyte Chemoattractant Proteins 4 (MCP-4/CCL13) is a member of a distinct, structurally-related subclass of CC chemokines mainly involved in recruitment of eos...
CCL24 Protein, Human, Recombinant (hFc)
TMPK-00704
C-C motif chemokine ligand 24 (CCL24) is a chemokine that regulates inflammatory and fibrotic activities through its receptor, C-C motif chemokine receptor (CCR3...
CX3CL1/Fractalkine Protein, Mouse, Recombinant (His & Avi), Biotinylated
TMPK-00721
Fractalkine/CX3C chemokine ligand 1 (CX3CL1) is a chemokine involved in the anticancer function of lymphocytes-mainly NK cells, T cells and dendritic cells. Its ...
CXCL13/BCA-1 Protein, Mouse, Recombinant (hFc)
TMPK-00734
Recent studies have implicated chemokines in microglial activation and pathogenesis of neuropathic pain. C-X-C motif chemokine 13 (CXCL13) is a B lymphocyte chem...
CXCL13/BCA-1 Protein, Mouse, Recombinant (His)
TMPK-00735
Recent studies have implicated chemokines in microglial activation and pathogenesis of neuropathic pain. C-X-C motif chemokine 13 (CXCL13) is a B lymphocyte chem...
MCP-1/CCL2 Protein, Cynomolgus, Recombinant (His)
TMPK-00916
MCP-1/CCL2 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 9.79 kDa and the acces...
CCL24 Protein, Mouse, Recombinant (hFc)
TMPK-01195
C-C motif chemokine ligand 24 (CCL24) is a chemokine that regulates inflammatory and fibrotic activities through its receptor, C-C motif chemokine receptor (CCR3...
CCL24 Protein, Mouse, Recombinant (His)
TMPK-01196
C-C motif chemokine ligand 24 (CCL24) is a chemokine that regulates inflammatory and fibrotic activities through its receptor, C-C motif chemokine receptor (CCR3...
CXCL4 Protein, Mouse, Recombinant (hFc)
TMPK-01248
Chemokines regulate leukocyte migration during physiological and pathological conditions. It is currently accepted that these chemotactic cytokines are also impo...
CCL24 Protein, Cynomolgus, Recombinant (His)
TMPK-01265
C-C motif chemokine ligand 24 (CCL24) is a chemokine that regulates inflammatory and fibrotic activities through its receptor, C-C motif chemokine receptor (CCR3...
CXCL10 Protein, Cynomolgus, Recombinant (His)
TMPK-01269
C-X-C motif ligand 10 (CXCL10), or interferon-inducible protein-10, is a small chemokine belonging to the CXC chemokine family. Its members are responsible for l...
CXCL14 Protein, Mouse, Recombinant
TMPY-00001
CXCL14 Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 9.4 kDa and the accession number is Q9WUQ5.
GRO beta/CXCL2 Protein, Human, Recombinant
TMPY-00006
GRO beta/CXCL2 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 7.9 kDa and the accession number is A0A02...
CXCL1 Protein, Rat, Recombinant
TMPY-00008
CXCL1 Protein, Rat, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 7.9 kDa and the accession number is P14095.
GRO beta/CXCL2 Protein, Rat, Recombinant
TMPY-00009
GRO beta/CXCL2 Protein, Rat, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 7.6 kDa and the accession number is A6KKD4....
MPIF-1/CCL23 Protein, Human, Recombinant (His)
TMPY-00168
MPIF-1/CCL23 Protein, Human, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 9.9 kDa and the accession number is P55773.3...
CXCL7 Protein, Mouse, Recombinant (aa 40-113, His)
TMPY-00218
CXCL7 Protein, Mouse, Recombinant (aa 40-113, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 10.4 kDa and the acc...
MDC Protein, Mouse, Recombinant (His)
TMPY-00305
MDC Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 9.9 kDa and the accession number ...
CXCL1 Protein, Mouse, Recombinant
TMPY-00433
CXCL1 Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 8.3 kDa and the accession number is A2RTH0.
CXCL7 Protein, Human, Recombinant (His)
TMPY-00469
CXCL7 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 9.9 kDa and the accession numbe...
MCP-4 Protein, Human, Recombinant (His)
TMPY-00564
Monocyte Chemoattractant Proteins 4 (MCP-4/CCL13) is a member of a distinct, structurally-related subclass of CC chemokines mainly involved in recruitment of eos...
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TargetMol