B cells, also known as B lymphocytes, are a type of white blood cell of the lymphocyte subtype. They function in the humoral immunity component of the adaptive immune system. In mammals, B cells mature in the bone marrow. B cell activation occurs in the secondary lymphoid organs (SLOs), such as the spleen and lymph nodes. After B cells mature in the bone marrow, they migrate through the blood to SLOs, which receive a constant supply of antigen through circulating lymph. At the SLO, B cell activation begins when the B cell binds to an antigen via its B-cell receptors (BCR).
Immature B cells express CD19, CD20, CD34, CD38, and CD45R. Most mature B cells express IgM, CD19, CD20, and CD22. Activated B cells express CD30. Plasma B cells could not express CD19, but could express CD78.
Cat No. | product name / Synonyms | Species | Expression System |
---|---|---|---|
TMPK-00447 | CD45 Protein, Human, Recombinant (aa 26-577, hFc)
CD45 Protein, Human, Recombinant (aa 26-577, hFc)
|
Human | HEK293 Cells |
PTPRC (also known as CD45),T cells require the protein tyrosine phosphatase CD45 to detect and respond to antigen because it activates the Src family kinase Lck,... | |||
TMPK-00510 | BAFF/TNFSF13B Trimer Protein, Cynomolgus, Recombinant (His & Avi, Flag), Biotinylated
BAFF/TNFSF13B Trimer Protein, Cynomolgus, Recombinant (His & Avi, Flag), Biotinylated
|
Cynomolgus | HEK293 Cells |
B-cell activating factor (BAFF) also known as tumor necrosis factor ligand superfamily member 13B is a protein that in humans is encoded by the TNFSF13B gene.BAF... | |||
TMPK-00511 | BAFF/TNFSF13B Trimer Protein, Cynomolgus, Recombinant (His & Avi)
BAFF/TNFSF13B Trimer Protein, Cynomolgus, Recombinant (His & Avi)
|
Cynomolgus | HEK293 Cells |
B-cell activating factor (BAFF) also known as tumor necrosis factor ligand superfamily member 13B is a protein that in humans is encoded by the TNFSF13B gene.BAF... | |||
TMPK-00518 | CD44 Protein, Cynomolgus, Recombinant (His)
CD44 Protein, Cynomolgus, Recombinant (His)
|
Cynomolgus | HEK293 Cells |
CD44 is a hyaluronan binding cell surface signal transducing receptor that influences motility, cell survival and proliferation as well as the formation of tumor... | |||
TMPK-00593 | Syndecan-1 Protein, Human, Recombinant (His & Avi), Biotinylated
Syndecan-1 Protein, Human, Recombinant (His & Avi), Biotinylated
|
Human | HEK293 Cells |
Liver diseases such as liver cirrhosis, primary and metastatic liver cancers are still a major medical challenge. Syndecan-1 is one of the most important proteog... | |||
TMPK-00594 | Syndecan-1 Protein, Human, Recombinant (aa 23-254, hFc)
Syndecan-1 Protein, Human, Recombinant (aa 23-254, hFc)
|
Human | HEK293 Cells |
Liver diseases such as liver cirrhosis, primary and metastatic liver cancers are still a major medical challenge. Syndecan-1 is one of the most important proteog... | |||
TMPK-00595 | Syndecan-1 Protein, Human, Recombinant (aa 23-254, His)
Syndecan-1 Protein, Human, Recombinant (aa 23-254, His)
|
Human | HEK293 Cells |
Liver diseases such as liver cirrhosis, primary and metastatic liver cancers are still a major medical challenge. Syndecan-1 is one of the most important proteog... | |||
TMPK-00642 | CD5 Protein, Rhesus macaque, Recombinant (His & Avi)
CD5 Protein, Rhesus macaque, Recombinant (His & Avi)
|
Rhesus | HEK293 Cells |
CD5: a type I transmembrane protein found on T cells, thymocytes, and some B cells that is a ligand for CD72 and is involved in cellular activation or adhesion; ... | |||
TMPK-00643 | CD5 Protein, Rhesus macaque, Recombinant (His & Avi), Biotinylated
CD5 Protein, Rhesus macaque, Recombinant (His & Avi), Biotinylated
|
Rhesus | HEK293 Cells |
CD5: a type I transmembrane protein found on T cells, thymocytes, and some B cells that is a ligand for CD72 and is involved in cellular activation or adhesion; ... | |||
TMPK-00653 | B7-2 Protein, Cynomolgus, Recombinant (His)
B7-2 Protein, Cynomolgus, Recombinant (His)
|
Cynomolgus | HEK293 Cells |
B7-1 and B7-2 are homologous costimulatory ligands expressed on the surface of antigen presenting cells (APCs). Binding of these molecules to the T cell costimul... | |||
TMPK-00674 | CD24 Protein, Cynomolgus, Recombinant (hFc)
CD24 Protein, Cynomolgus, Recombinant (hFc)
|
Cynomolgus | HEK293 Cells |
CD24 is a sialoglycoprotein expressed at the surface of most B lymphocytes and differentiating neuroblasts. It is also expressed on neutrophils and neutrophil pr... | |||
TMPK-00675 | CD24 Protein (Primary Amine Labeling), Cynomolgus, Recombinant (hFc), Biotinylated
CD24 Protein (Primary Amine Labeling), Cynomolgus, Recombinant (hFc), Biotinylated
|
Cynomolgus | HEK293 Cells |
CD24 is a sialoglycoprotein expressed at the surface of most B lymphocytes and differentiating neuroblasts. It is also expressed on neutrophils and neutrophil pr... | |||
TMPK-00777 | CD117 Protein, Mouse, Recombinant (His)
CD117 Protein, Mouse, Recombinant (His)
|
Mouse | HEK293 Cells |
The c-kit proto-oncogen (CD 117) has been shown to be present in several cell types including normal and neoplastic hemopoietic cells. Among normal BM cells, CD1... | |||
TMPK-00805 | CD117 Protein, Human, Recombinant (His & Avi), Biotinylated
CD117 Protein, Human, Recombinant (His & Avi), Biotinylated
|
Human | HEK293 Cells |
The c-kit proto-oncogen (CD 117) has been shown to be present in several cell types including normal and neoplastic hemopoietic cells. Among normal BM cells, CD1... | |||
TMPK-00809 | CD37 Protein, Human, Recombinant (His)
CD37 Protein, Human, Recombinant (His)
|
Human | HEK293 Cells |
CD37 is a tetraspanin expressed prominently on the surface of B cells. It is an attractive molecular target exploited in the immunotherapy of B cell-derived lymp... | |||
TMPK-00840 | CD21 Protein, Mouse, Recombinant (His)
CD21 Protein, Mouse, Recombinant (His)
|
Mouse | HEK293 Cells |
A natural soluble form of CD21 that is cleaved from lymphocyte membrane CD21 circulates in normal human serum. Soluble CD21 retains the capacity to bind iC3b and... | |||
TMPK-00842 | CD21 Protein, Human, Recombinant (His)
CD21 Protein, Human, Recombinant (His)
|
Human | HEK293 Cells |
CD21 mRNA expression, an EBV-entry receptor, was transiently detected in NK cells after exosome treatment, and levels decreased after further culture. CD21 prote... | |||
TMPK-00880 | B7-2 Protein, Human, Recombinant (His & Avi)
B7-2 Protein, Human, Recombinant (His & Avi)
|
Human | HEK293 Cells |
B7-1 and B7-2 are homologous costimulatory ligands expressed on the surface of antigen presenting cells (APCs). Binding of these molecules to the T cell costimul... | |||
TMPK-00881 | B7-2 Protein, Human, Recombinant (His & Avi), Biotinylated
B7-2 Protein, Human, Recombinant (His & Avi), Biotinylated
|
Human | HEK293 Cells |
B7-1 and B7-2 are homologous costimulatory ligands expressed on the surface of antigen presenting cells (APCs). Binding of these molecules to the T cell costimul... | |||
TMPK-00882 | B7-2 Protein, Human, Recombinant (hFc)
B7-2 Protein, Human, Recombinant (hFc)
|
Human | HEK293 Cells |
B7-1 and B7-2 are homologous costimulatory ligands expressed on the surface of antigen presenting cells (APCs). Binding of these molecules to the T cell costimul... |