B cells, also known as B lymphocytes, are a type of white blood cell of the lymphocyte subtype. They function in the humoral immunity component of the adaptive immune system. In mammals, B cells mature in the bone marrow. B cell activation occurs in the secondary lymphoid organs (SLOs), such as the spleen and lymph nodes. After B cells mature in the bone marrow, they migrate through the blood to SLOs, which receive a constant supply of antigen through circulating lymph. At the SLO, B cell activation begins when the B cell binds to an antigen via its B-cell receptors (BCR).
Immature B cells express CD19, CD20, CD34, CD38, and CD45R. Most mature B cells express IgM, CD19, CD20, and CD22. Activated B cells express CD30. Plasma B cells could not express CD19, but could express CD78.
Cat No. | product name / Synonyms | Species | Expression System |
---|---|---|---|
TMPY-05197 | BCMA/TNFRSF17 Protein, Human, Recombinant (mFc)
BCMA/TNFRSF17 Protein, Human, Recombinant (mFc)
|
Human | HEK293 |
Tumor necrosis factor receptor superfamily, member 17 (TNFRSF17), also known as B cell maturation antigen (BCMA) or CD269 antigen, is a member of the TNF-recepto... | |||
TMPY-05223 | Siglec-2/CD22 Protein, Human, Recombinant (His), Biotinylated
Siglec-2/CD22 Protein, Human, Recombinant (His), Biotinylated
|
Human | HEK293 |
CD22 is a member of the immunoglobulin superfamily, SIGLEC family of lectins. It is first expressed in the cytoplasm of pro-B and pre-B cells, and on the surface... | |||
TMPY-05246 | CD86 Protein, Human, Recombinant (His), Biotinylated
CD86 Protein, Human, Recombinant (His), Biotinylated
|
Human | HEK293 |
CD86, also known as B-lymphocyte activation antigen B7-2 (referred to as B70), is a member of the cell surface immunoglobulin superfamily. B7-2 exists predominan... | |||
TMPY-05298 | CD24 Protein, Human, Recombinant (rFc)
CD24 Protein, Human, Recombinant (rFc)
|
Human | HEK293 |
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified... | |||
TMPY-05299 | CD24 Protein, Human, Recombinant (mFc)
CD24 Protein, Human, Recombinant (mFc)
|
Human | HEK293 |
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified... | |||
TMPY-05316 | Siglec-2/CD22 Protein, Human, Recombinant (aa 176-687, His), Biotinylated
Siglec-2/CD22 Protein, Human, Recombinant (aa 176-687, His), Biotinylated
|
Human | HEK293 |
CD22 is a member of the immunoglobulin superfamily, SIGLEC family of lectins. It is first expressed in the cytoplasm of pro-B and pre-B cells, and on the surface... | |||
TMPY-05328 | BCMA/TNFRSF17 Protein, Human, Recombinant (His & Avi)
BCMA/TNFRSF17 Protein, Human, Recombinant (His & Avi)
|
Human | HEK293 |
Tumor necrosis factor receptor superfamily, member 17 (TNFRSF17), also known as B cell maturation antigen (BCMA) or CD269 antigen, is a member of the TNF-recepto... | |||
TMPY-05359 | CD40 Protein, Human, Recombinant (mFc)
CD40 Protein, Human, Recombinant (mFc)
|
Human | HEK293 |
CD40, also known as TNFRSF5, is a member of the TNF receptor superfamily which are single transmembrane-spanning glycoproteins. CD40 protein plays an essential r... | |||
TMPY-05377 | IL-7R alpha/CD127 Protein, Human, Recombinant (hFc)
IL-7R alpha/CD127 Protein, Human, Recombinant (hFc)
|
Human | HEK293 |
Interleukin 7 Receptor alpha (IL-7RA), also known as CD127, is a 75 kDa hematopoietic receptor superfamily member that plays an important role in lymphocyte diff... | |||
TMPY-05379 | B7-1 Protein, Human, Recombinant (hFc)
B7-1 Protein, Human, Recombinant (hFc)
|
Human | HEK293 |
The B-lymphocyte activation antigen B7-1 (referred to as B7), also known as CD80, is a member of cell surface immunoglobulin superfamily and is expressed on the ... | |||
TMPY-05385 | BCMA/TNFRSF17 Protein, Human, Recombinant (hFc)
BCMA/TNFRSF17 Protein, Human, Recombinant (hFc)
|
Human | HEK293 |
Tumor necrosis factor receptor superfamily, member 17 (TNFRSF17), also known as B cell maturation antigen (BCMA) or CD269 antigen, is a member of the TNF-recepto... | |||
TMPY-05386 | CD86 Protein, Mouse, Recombinant (hFc)
CD86 Protein, Mouse, Recombinant (hFc)
|
Mouse | HEK293 |
CD86, also known as B-lymphocyte activation antigen B7-2 (referred to as B70), is a member of the cell surface immunoglobulin superfamily. B7-2 exists predominan... | |||
TMPY-05390 | CD86 Protein, Human, Recombinant (hFc)
CD86 Protein, Human, Recombinant (hFc)
|
Human | HEK293 |
CD86, also known as B-lymphocyte activation antigen B7-2 (referred to as B70), is a member of the cell surface immunoglobulin superfamily. B7-2 exists predominan... | |||
TMPY-05391 | CD28 Protein, Mouse, Recombinant (hFc)
CD28 Protein, Mouse, Recombinant (hFc)
|
Mouse | HEK293 |
CD28 (Cluster of Differentiation 28) is a disulphide-bonded glycoprotein belonging to the immunoglobulin (Ig) superfamily, and structurally consists of a single ... | |||
TMPY-05415 | CD27/TNFRSF7 Protein, Human, Recombinant (hFc & Avi), Biotinylated
CD27/TNFRSF7 Protein, Human, Recombinant (hFc & Avi), Biotinylated
|
Human | HEK293 |
CD27, also known as TNFRSF7, is a member of the TNF-receptor superfamily limited to cells of the lymphoid lineage, and exists as both a dimeric glycoprotein on t... | |||
TMPY-05420 | CD19 Protein, Cynomolgus, Rhesus, Recombinant (His)
CD19 Protein, Cynomolgus, Rhesus, Recombinant (His)
|
Cynomolgus,Rhesus | HEK293 |
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified... | |||
TMPY-05422 | CD5 Protein, Human, Recombinant (hFc)
CD5 Protein, Human, Recombinant (hFc)
|
Human | HEK293 |
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified... | |||
TMPY-05425 | CD40 Protein, Mouse, Recombinant (hFc)
CD40 Protein, Mouse, Recombinant (hFc)
|
Mouse | HEK293 |
CD40, also known as TNFRSF5, is a member of the TNF receptor superfamily which are single transmembrane-spanning glycoproteins. CD40 protein plays an essential r... | |||
TMPY-05445 | CD27/TNFRSF7 Protein, Human, Recombinant (hFc)
CD27/TNFRSF7 Protein, Human, Recombinant (hFc)
|
Human | HEK293 |
CD27, also known as TNFRSF7, is a member of the TNF-receptor superfamily limited to cells of the lymphoid lineage, and exists as both a dimeric glycoprotein on t... | |||
TMPY-05567 | BCMA/TNFRSF17 Protein, Human (His & hFc), FITC conjugated
BCMA/TNFRSF17 Protein, Human (His & hFc), FITC conjugated
|
Human | HEK293 |
Tumor necrosis factor receptor superfamily, member 17 (TNFRSF17), also known as B cell maturation antigen (BCMA) or CD269 antigen, is a member of the TNF-recepto... |