store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Vinorelbine ditartrate (KW-2307), a semi-synthetic vinca alkaloid, interacts with tubulin resulting in mitosis inhibition.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | In stock | $ 30.00 | |
10 mg | In stock | $ 51.00 | |
25 mg | In stock | $ 108.00 | |
50 mg | In stock | $ 183.00 | |
100 mg | In stock | $ 288.00 | |
500 mg | In stock | $ 688.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 61.00 |
Description | Vinorelbine ditartrate (KW-2307), a semi-synthetic vinca alkaloid, interacts with tubulin resulting in mitosis inhibition. |
Targets&IC50 | Anti-mitotic:1.25 nM |
In vitro | Vinorelbine inhibits microtubule assembly by inducing tubulin aggregation into spirals and paracrystals. [1] Vinorelbine shows potent antiproliferative activity against a series of tumor cells, including human melanoma, non-small-cell lung cancer, breast cancer, etc. [2][3][4] |
In vivo | In vivo, Vinorelbine also shows antitumour activity against a series of subcutaneously-implanted human tumour xenografts. [5] |
Source |
Synonyms | Vinorelbine Tartrate, Nor-5'-anhydrovinblastine ditartrate, KW-2307, Navelbine tartrate |
Molecular Weight | 1079.11 |
Formula | C45H54N4O8·2C4H6O6 |
CAS No. | 125317-39-7 |
store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: 107.9 mg/mL (100 mM)
DMSO: 107.9 mg/mL (100 mM)
You can also refer to dose conversion for different animals. More
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Vinorelbine ditartrate 125317-39-7 Autophagy Cytoskeletal Signaling Microtubule Associated Vinorelbine Tartrate Nor-5'-anhydrovinblastine ditartrate Inhibitor KW-2307 Nor-5'-anhydrovinblastine Vinorelbine KW 2307 Microtubule/Tubulin Navelbine tartrate Nor-5'-anhydrovinblastine Ditartrate KW2307 Vinorelbine Ditartrate inhibit Navelbine Tartrate inhibitor