Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Salcaprozate sodium (SNAC), an oral absorption promoter, serves as a potent delivery agent for oral heparin and insulin by enhancing passive transcellular permeation through small intestinal epithelia. This is achieved through its capability to increase lipophilicity via non-covalent macromolecule complexation.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
500 mg | In stock | $ 59.00 | |
1 g | In stock | $ 98.00 |
Description | Salcaprozate sodium (SNAC), an oral absorption promoter, serves as a potent delivery agent for oral heparin and insulin by enhancing passive transcellular permeation through small intestinal epithelia. This is achieved through its capability to increase lipophilicity via non-covalent macromolecule complexation. |
In vitro | Salcaprozate sodium(SNAC ;12.5-400 μg/mL;?24 h) has no toxicity to Caco-2 cells, and the survival percentage is above 90% when SNAC is 200 μg/mL.?SNAC (50 and 200 μg/mL) improves the apparent permeability coeffcient (Papp) of RA and SA-B by 2.14-fold and 3.68-fold compared with the Papp of SAs solution[1]. |
Synonyms | SNAC |
Molecular Weight | 301.32 |
Formula | C15H20NNaO4 |
CAS No. | 203787-91-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 100 mg/mL (331.88 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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Salcaprozate sodium 203787-91-1 Others inhibit delivery Inhibitor non-covalent absorption lipophilicity permeation promoter transcellular across complexation Salcaprozate SNAC macromolecule inhibitor