Powder: -20°C for 3 years | In solvent: -80°C for 1 year
PF-05186462 (PF-05150122) is a potent, state-dependent, subtype selective Nav1.7 inhibitor with IC50 of 21 nM, no significant activity against Nav1.5.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 133.00 | |
5 mg | In stock | $ 302.00 | |
10 mg | In stock | $ 453.00 | |
25 mg | In stock | $ 747.00 | |
50 mg | In stock | $ 1,050.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 389.00 |
Description | PF-05186462 (PF-05150122) is a potent, state-dependent, subtype selective Nav1.7 inhibitor with IC50 of 21 nM, no significant activity against Nav1.5. |
Targets&IC50 | human Nav1.7:21 nM (IC50) |
Synonyms | PF-05150122 |
Molecular Weight | 531.89 |
Formula | C19H10ClF4N5O3S2 |
CAS No. | 1235406-03-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 11 mg/mL (20.68 mM)
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
PF-05186462 1235406-03-7 Membrane transporter/Ion channel Sodium Channel acute Na channels PF05186462 inhibit chronic voltage PF-05150122 channel Na+ channels Inhibitor Nav1.7 pain PF 05150122 PF 05186462 sodium PF05150122 inhibitor