store at low temperature,keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Grossamide (GSE) Grossamide is a lignan amide derived from thioguanosine.6-Thioguanosine (GSE) is a selective and potent miR-210 (miRNA-210) inhibitor.6-Thioguanosine (GSE) is a selective and potent miR-210 (miRNA-210) inhibitor.6-Thioguanosine (GSE) is a selective and potent miR-210 (miRNA-210) inhibitor that inhibits pre-miR-210 processing and induces apoptosis in breast cancer cells.
Pack Size | Availability | Price/USD | Quantity |
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1 mg | In stock | $ 978.00 |
Description | Grossamide (GSE) Grossamide is a lignan amide derived from thioguanosine.6-Thioguanosine (GSE) is a selective and potent miR-210 (miRNA-210) inhibitor.6-Thioguanosine (GSE) is a selective and potent miR-210 (miRNA-210) inhibitor.6-Thioguanosine (GSE) is a selective and potent miR-210 (miRNA-210) inhibitor that inhibits pre-miR-210 processing and induces apoptosis in breast cancer cells. |
In vitro | In the presence of Grossamide, the production of inflammatory molecules mediated by LPS is downregulated[1]. Grossamide, when applied at concentrations ranging from 0 to 20 μM for 1 hour, demonstrates a dose-dependent inhibition of mRNA levels of TNF-α and IL-6. Additionally, Grossamide inhibits LPS-induced activation of NF-κB, as well as the expression of LPS-induced TLR4 and MyD88, all without inducing cytotoxicity[1]. |
Molecular Weight | 624.68 |
Formula | C36H36N2O8 |
CAS No. | 80510-06-1 |
store at low temperature,keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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Grossamide 80510-06-1 Immunology/Inflammation NO Synthase inhibitor inhibit