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Cell Cycle/Checkpoint cell cycle arrest Gracillin

Gracillin

Catalog No. T3774   CAS 19083-00-2

Gracillin can induce cell cycle arrest, oxidative stress, and apoptosis in HL60 cells, and has the potential to be developed as an antitumor agent. Gracillin can be selected as lead compounds for the development of new drugs against I. multifiliis.

Gracillin, CAS 19083-00-2
Pack Size Availability Price/USD Quantity
2 mg In stock 74.00
5 mg In stock 104.00
10 mg In stock 185.00
25 mg In stock 311.00
1 mL * 10 mM (in DMSO) In stock 180.00
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Purity 99.70%
Purity 99.86%
Biological Description
Chemical Properties
Storage & Solubility Information
Description Gracillin can induce cell cycle arrest, oxidative stress, and apoptosis in HL60 cells, and has the potential to be developed as an antitumor agent. Gracillin can be selected as lead compounds for the development of new drugs against I. multifiliis.
Targets&IC50 cell cycle arrest
Molecular Weight 885.05
Formula C45H72O17
CAS No. 19083-00-2

Storage

0-4℃ for short term (days to weeks), or -20℃ for long term (months).

Solubility Information

DMSO: 113 mM

( < 1 mg/ml refers to the product slightly soluble or insoluble )

Citations

References and Literature
1. Chen CR,et al.Gracillin induces apoptosis in HL60 human leukemic cell line via oxidative stress and cell cycle arrest of G1. Pharmazie. 2015 Mar;70(3):199-204. 1. Chen CR,et al.Gracillin induces apoptosis in HL60 human leukemic cell line via oxidative stress and cell cycle arrest of GPharmazie. 2015 Mar;70(3):199-204. 2. Zheng W,et al.Antiparasitic efficacy of Gracillin and Zingibernsis newsaponin from Costus speciosus (Koen ex. Retz) Sm. against Ichthyophthirius multifiliis.Parasitology. 2015 Mar;142(3):473-9. 3. Chen CR et al. Gracillin induces apoptosis in HL60 human leukemic cell line via oxidative stress and cell cycle arrest of G1. Pharmazie. 2015 Mar;70(3):199-204.

Related compound libraries

This product is contained In the following compound libraries:
Bioactive Compound Library Natural Compound Library for HTS Anti-cancer Compound Library Selected Plant-sourced Compound Library Cell cycle related Compound Library

Related Products

Related compounds with same targets
Kaempferitrin Gracillin Ginsenoside C-K 4-Oxofenretinide

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