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Estetrol

Catalog No. T15248 CAS 15183-37-6

Synonyms: Donesta

Estetrol(Donesta) is an orally available, selective modulator of the estrogen receptor, a naturally occurring estrogen synthesized by the human fetal liver during pregnancy.Estetrol has effects on the endometrium or central nervous system, but is antagonistic to the breast.Estetrol may help to reduce thrombosis at low concentrations. Estetrol may be used to relieve menopausal symptoms.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

Estetrol, CAS 15183-37-6

Pack Size	Availability	Price/USD
1 mg	In stock	$ 128.00
5 mg	In stock	$ 326.00
10 mg	In stock	$ 486.00
25 mg	In stock	$ 778.00
50 mg	In stock	$ 1,060.00
100 mg	In stock	$ 1,430.00
1 mL * 10 mM (in DMSO)	In stock	$ 443.00

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Purity: 99.83%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Synonyms	Donesta
Molecular Weight	304.38
Formula	C18H24O4
CAS No.	15183-37-6

Storage

store at low temperature,keep away from direct sunlight

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 90 mg/mL (295.68 mM), Sonication is recommended.

References and Literature

1. Valéra MC, et al. Effect of estetrol, a selective nuclear estrogen receptor modulator, in mouse models of arterial and venous thrombosis. Mol Cell Endocrinol. 2018 Dec 5;477:132-139. 2. Montt-Guevara MM, et al. Estetrol Modulates Endothelial Nitric Oxide Synthesis in Human Endothelial Cells. Front Endocrinol (Lausanne). 2015 Jul 22;6:111.

Related compound libraries

This product is contained In the following compound libraries：

Drug Repurposing Compound Library EMA Approved Drug Library Anti-Cancer Approved Drug Library Bioactive Compounds Library Max FDA-Approved & Pharmacopeia Drug Library Approved Drug Library FDA-Approved Drug Library Bioactive Compound Library

Related Products

Related compounds with same targets

Pipendoxifene hydrochloride Camizestrant TFA Hexestrol Quinestrol (±)-Equol G36 CMP8 Raloxifene hydrochloride

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Estetrol 15183-37-6 Endocrinology/Hormones Metabolism Estrogen Receptor/ERR Endogenous Metabolite Donesta inhibitor inhibit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.