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EZM0414

Catalog No. T9969 CAS 2411748-50-8

EZM0414 is a potent, selective, orally bioavailable inhibitor of SETD2 with IC50 of 18 nM in SETD2 biochemical assay and IC50 of 34 nM in a cellular assay. EZM0414 can be used for the research of relapsed or refractory multiple myeloma and diffuse large B-cell lymphoma [1].

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

EZM0414, CAS 2411748-50-8

Pack Size	Availability	Price/USD
1 mg	In stock	$ 279.00
5 mg	In stock	$ 688.00
10 mg	In stock	$ 978.00
25 mg	In stock	$ 1,460.00
50 mg	In stock	$ 1,960.00
100 mg	In stock	$ 2,650.00

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Purity: 98.9%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Molecular Weight	400.49
Formula	C22H29FN4O2
CAS No.	2411748-50-8

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 115 mg/mL (287.15 mM), Sonication and heating to 60℃ are recommended.

References and Literature

1. Jennifer Totman, et al. Pharmacologic Inhibition of the Histone Methyltransferase SETD2 with EZM0414 As a Novel Therapeutic Strategy in Relapsed or Refractory Multiple Myeloma and Diffuse Large B-cell Lymphoma.

Related compound libraries

This product is contained In the following compound libraries：

Anti-Cancer Drug Library Anti-Cancer Clinical Compound Library Drug Repurposing Compound Library Anti-Cancer Active Compound Library Inhibitor Library Immunology/Inflammation Compound Library Bioactive Compounds Library Max Bioactive Compound Library Clinical Compound Library Epigenetics Compound Library

Related Products

Related compounds with same targets

EPZ020411 2HCl (1700663-41-7(free base)) OICR-9429 Pinometostat GSK2807 Trifluoroacetate SGC-iMLLT EEDi-5285 GSK126 UNC6934

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

EZM0414 2411748-50-8 Chromatin/Epigenetic Histone Methyltransferase EZM 0414 EZM-0414 inhibitor inhibit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.