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Corosolic acid

Catalog No. T3391   CAS 4547-24-4
Synonyms: Corsolic acid, 2α-Hydroxyursolic acid, Glucosol, Colosolic acid, Colosic acid

Corosolic acid (Colosic acid) contains anti-angiogenic activity that can suppress FAK signaling induced by angiopoietin-1. Corosolic acid exerts anticancer activities against HCC, colon, and colorectal Y cells, by inducing apoptosis and promoting the N-terminal phosphorylation and subsequent proteasomal degradation of β-catenin.

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Corosolic acid Chemical Structure
Corosolic acid, CAS 4547-24-4
Pack Size Availability Price/USD Quantity
5 mg In stock $ 39.00
10 mg In stock $ 59.00
25 mg In stock $ 113.00
50 mg In stock $ 172.00
100 mg In stock $ 255.00
1 mL * 10 mM (in DMSO) In stock $ 43.00
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Purity: 99.52%
Purity: 99.5%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Corosolic acid (Colosic acid) contains anti-angiogenic activity that can suppress FAK signaling induced by angiopoietin-1. Corosolic acid exerts anticancer activities against HCC, colon, and colorectal Y cells, by inducing apoptosis and promoting the N-terminal phosphorylation and subsequent proteasomal degradation of β-catenin.
Source
Synonyms Corsolic acid, 2α-Hydroxyursolic acid, Glucosol, Colosolic acid, Colosic acid
Molecular Weight 472.7
Formula C30H48O4
CAS No. 4547-24-4

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 86 mg/mL(181.9 mM)

Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.: Soluble

TargetMolReferences and Literature

1. Yoo KH, et al. Phytother Res. 2015 May;29(5):714-23. 2. Feng X, et al. Nat Prod Res. 2014;28(21):1879-86. 3. Kim JH, et al. Food Chem Toxicol. 2014 May;67:87-95. 4. Sung B, et al. Int J Mol Med. 2014 Apr;33(4):943-9. 6. Ki Hyun Yoo, et al. Corosolic Acid Exhibits Anti-angiogenic and Anti-lymphangiogenic Effects on In Vitro Endothelial Cells and on an In Vivo CT-26 Colon Carcinoma Animal Model. Phytotherapy Research, 2015 , 29 (5): 14–723

Related compound libraries

This product is contained In the following compound libraries:
Miao medicine Compound Library Tyrosine Kinase Inhibitor Library Anti-Cancer Active Compound Library Traditional Chinese Medicine Monomer Library Terpene Natural Product Library PBCRBS Traditional Chinese Medicine Compound Library Anti-Aging Compound Library Anti-COVID-19 Traditional Chinese Medicine Compound Library ReFRAME Related Library Selected Plant-Sourced Compound Library

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Keywords

Corosolic acid 4547-24-4 Angiogenesis Autophagy Cytoskeletal Signaling Tyrosine Kinase/Adaptors FAK inhibit Corsolic acid 2α-Hydroxyursolic acid Glucosol Colosolic acid 2alpha-Hydroxyursolic acid Inhibitor 2a-Hydroxyursolic acid Colosic acid inhibitor

 

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