Powder: -20°C for 3 years | In solvent: -80°C for 1 year
5-Methoxytryptophol (2-(5-Methoxy-1H-indol-3-yl)ethanol) is a pineal indoleamine derived from serotonin shown to be biologically active in a number of species.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
10 mg | In stock | $ 30.00 | |
25 mg | In stock | $ 64.00 | |
50 mg | In stock | $ 98.00 | |
100 mg | In stock | $ 150.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 39.00 |
Description | 5-Methoxytryptophol (2-(5-Methoxy-1H-indol-3-yl)ethanol) is a pineal indoleamine derived from serotonin shown to be biologically active in a number of species. |
In vitro | In MC3T3-E1 cells, most of the 5-methoxytryptophol doses reduced slightly the metabolic activity of osteoblasts. After 14 days of cell culture, Rankl mRNA levels were decreased. 5-methoxytryptophol also induced a high osteocalcin secretion and mineralization capacity. In RAW264.7 cells, 5-methoxytryptophol decreased the number of osteoclast formed and its activity. 5-methoxytryptophol promoted activation of the ERK1/2 pathway through the phosphorylation of ERK, while LUZ addition suppressed this effect. In conclusion, 5-methoxytryptophol inhibits osteoclastogenesis and promoting osteoblast differentiation[3]. |
Synonyms | 2-(5-Methoxy-1H-indol-3-yl)ethanol, Methoxytryptophol |
Molecular Weight | 191.23 |
Formula | C11H13NO2 |
CAS No. | 712-09-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 88 mg/mL (460.18 mM)
You can also refer to dose conversion for different animals. More
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5-Methoxytryptophol 712-09-4 Metabolism Endogenous Metabolite 2-(5-Methoxy-1H-indol-3-yl)ethanol Inhibitor Methoxytryptophol 5 Methoxytryptophol 5Methoxytryptophol inhibit inhibitor