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5-HT Receptor

5-hydroxytryptamine receptors or 5-HT receptors, or serotonin receptors, are a group of G protein-coupled receptor and ligand-gated ion channels found in the central and peripheral nervous systems. They mediate both excitatory and inhibitory neurotransmission.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T1528 Azasetron hydrochloride 123040-16-4 99.85%
Azasetron hydrochloride
Azasetron hydrochloride (Y-25130 HCl) is a 5-HT3 receptor antagonist which is used as an anti-emetic.
T3275 Nefazodone hydrochloride 82752-99-6 99.85%
Nefazodone hydrochloride
Nefazodone hydrochloride (Serzone) is a serotoninergic modulating antidepressant that is used in therapy of depression, aggressive behavior and panic disorder.
T8128 Mosapride 112885-41-3 99.85%
Mosapride
Mosapride (AS-4370) is a selective 5HT4 agonist
T30140 Arotinolol hydrochloride 68377-91-3 99.84%
Arotinolol hydrochloride
Arotinolol hydrochloride(Arotinolol HCl) is a non-selective α/β-adrenergic receptor blocker.Arotinolol hydrochloride inhibits the binding of the radioligand 125I...
T27020 Cilansetron 120635-74-7 99.84%
Cilansetron
Cilansetron is an effective and selective 5-HT3 receptor antagonist that can be used for related diseases caused by colitis.
T2815 Puerarin 3681-99-0 99.84%
Puerarin
Puerarin (Kakonein), also known as Kakonein, is a member of the class of compounds known as isoflavonoid C-glycosides. It is a 5-HT2C receptor antagonist.
TP1127 Nemifitide diTFA 204992-09-6 99.84%
Nemifitide diTFA
Nemifitide diTFA (INN 00835 diTFA) is a synthetic pentapeptide, a peptide like melanocyte suppressor factor (MIF) that can cross the blood-brain barrier and has ...
T22591 ATC 0175 hydrochloride 510733-97-8 99.84%
ATC 0175 hydrochloride
ATC 0175 hydrochloride is an orally active melanocyte concentrating hormone 1 receptor antagonist that is potent and selective. ATC 0175 hydrochloride has affini...
T1279 Vilazodone 163521-12-8 99.83%
Vilazodone
Vilazodone (SB659746A) is a selective serotonin (5-HT) reuptake inhibitor (SSRI) and a 5-HT-1A receptor partial agonist, with antidepressant and anti-anxiety act...
T4008 Metergoline 17692-51-2 99.83%
Metergoline
Metergoline (Methergoline) is a dopamine agonist and serotonin antagonist. It has been used similarly to BROMOCRIPTINE as a dopamine agonist and also for migrain...
T23382 Spiroxatrine 1054-88-2 99.83%
Spiroxatrine
Spiroxatrine (R 5188) is a selective and potent 5-HT1α and α2-adrenergic dual antagonist with sedative activity and inhibitory effects on 5-HT1α, 5-HT1 β, 5-HT2,...
T80805 WAY-607695 380469-52-3 99.82%
WAY-607695
WAY-607695 is a potential 5-HT1A receptor agonist.
T60325 Viloxazine 46817-91-8 99.82%
Viloxazine
Viloxazine (Viloxazin) (Viloxazin) is a dual-action compound that functions as a norepinephrine reuptake inhibitor and exhibits potent agonistic activity towards...
T4274 Melitracen hydrochloride 10563-70-9 99.82%
Melitracen hydrochloride
Melitracen hydrochloride (Thymeol hydrochloride) , an antidepressant, is used as potential dopamine D1/2 receptor antagonist to treat depression.
T60027 (+)-OSU 6162 160777-43-5 99.81%
(+)-OSU 6162
(+)-OSU 6162 (Piperidine, 3-[3-(methylsulfonyl)phenyl]-1-propyl-, (3R)-) is an agonist of 5-HT Receptor with anti-Alzheimer and antidepressant activities.
TN2437 Serotonin 50-67-9 99.81%
Serotonin
Serotonin (5-hydroxytryptamine) is a natural product from animals
T23318L SB 258585 209480-63-7 99.8%
SB 258585
SB 258585 is a selective 5-HT6 receptor antagonist.SB 258585 has a high affinity for individual receptor populations in cell lines with human recombinant 5-HT6 r...
T12262L1 NPS ALX Compound 4a hydrochloride(1:1) T12262L1 99.8%
NPS ALX Compound 4a hydrochloride(1:1)
NPS ALX Compound 4a hydrochloride(1:1) is a potent and selective 5-hydroxytryptamine6 (5-HT6) receptor antagonist, with an IC50 of 7.2 nM and a Ki of 0.2 nM.
T6648 Rotundine 483-14-7 99.8%
Rotundine
Rotundine (Gindarine) (L-tetrahydropalmatine, L-THP) is a selective dopamine D1 receptor antagonist with IC50 of 166 nM.
T8357 SB-200646 143797-63-1 99.8%
SB-200646
SB-200646 is a selective and potent antagonist of 5-HT2B/5-HT2C receptor
Azasetron hydrochloride
T1528
Azasetron hydrochloride (Y-25130 HCl) is a 5-HT3 receptor antagonist which is used as an anti-emetic.
Nefazodone hydrochloride
T3275
Nefazodone hydrochloride (Serzone) is a serotoninergic modulating antidepressant that is used in therapy of depression, aggressive behavior and panic disorder.
Mosapride
T8128
Mosapride (AS-4370) is a selective 5HT4 agonist
Arotinolol hydrochloride
T30140
Arotinolol hydrochloride(Arotinolol HCl) is a non-selective α/β-adrenergic receptor blocker.Arotinolol hydrochloride inhibits the binding of the radioligand 125I...
Cilansetron
T27020
Cilansetron is an effective and selective 5-HT3 receptor antagonist that can be used for related diseases caused by colitis.
Puerarin
T2815
Puerarin (Kakonein), also known as Kakonein, is a member of the class of compounds known as isoflavonoid C-glycosides. It is a 5-HT2C receptor antagonist.
Nemifitide diTFA
TP1127
Nemifitide diTFA (INN 00835 diTFA) is a synthetic pentapeptide, a peptide like melanocyte suppressor factor (MIF) that can cross the blood-brain barrier and has ...
ATC 0175 hydrochloride
T22591
ATC 0175 hydrochloride is an orally active melanocyte concentrating hormone 1 receptor antagonist that is potent and selective. ATC 0175 hydrochloride has affini...
Vilazodone
T1279
Vilazodone (SB659746A) is a selective serotonin (5-HT) reuptake inhibitor (SSRI) and a 5-HT-1A receptor partial agonist, with antidepressant and anti-anxiety act...
Metergoline
T4008
Metergoline (Methergoline) is a dopamine agonist and serotonin antagonist. It has been used similarly to BROMOCRIPTINE as a dopamine agonist and also for migrain...
Spiroxatrine
T23382
Spiroxatrine (R 5188) is a selective and potent 5-HT1α and α2-adrenergic dual antagonist with sedative activity and inhibitory effects on 5-HT1α, 5-HT1 β, 5-HT2,...
WAY-607695
T80805
WAY-607695 is a potential 5-HT1A receptor agonist.
Viloxazine
T60325
Viloxazine (Viloxazin) (Viloxazin) is a dual-action compound that functions as a norepinephrine reuptake inhibitor and exhibits potent agonistic activity towards...
Melitracen hydrochloride
T4274
Melitracen hydrochloride (Thymeol hydrochloride) , an antidepressant, is used as potential dopamine D1/2 receptor antagonist to treat depression.
(+)-OSU 6162
T60027
(+)-OSU 6162 (Piperidine, 3-[3-(methylsulfonyl)phenyl]-1-propyl-, (3R)-) is an agonist of 5-HT Receptor with anti-Alzheimer and antidepressant activities.
Serotonin
TN2437
Serotonin (5-hydroxytryptamine) is a natural product from animals
SB 258585
T23318L
SB 258585 is a selective 5-HT6 receptor antagonist.SB 258585 has a high affinity for individual receptor populations in cell lines with human recombinant 5-HT6 r...
NPS ALX Compound 4a hydrochloride(1:1)
T12262L1
NPS ALX Compound 4a hydrochloride(1:1) is a potent and selective 5-hydroxytryptamine6 (5-HT6) receptor antagonist, with an IC50 of 7.2 nM and a Ki of 0.2 nM.
Rotundine
T6648
Rotundine (Gindarine) (L-tetrahydropalmatine, L-THP) is a selective dopamine D1 receptor antagonist with IC50 of 166 nM.
SB-200646
T8357
SB-200646 is a selective and potent antagonist of 5-HT2B/5-HT2C receptor
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TargetMol