μ-opioid — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T4351	DAMGO	Dagol,DAGO,RX-783006	Opioid Receptor
	DAMGO (DAGO) is an opioid receptor agonist with the ability to affect the locomotive activity in rodents. Possible analgesic agent due to μ-opiod receptor interaction.		Opioid Receptor
T8991	BMS986187		Opioid Receptor
	BMS986187 is a novel Potent and Selective Positive Allosteric Modulators of the delta-Opioid Receptor.		Opioid Receptor
T1242	Alvimopan		Opioid Receptor
	Alvimopan (LY 246736) is a synthetic trans-3, 4-dimethyl-4-(3-hydroxyphenyl) piperidine with peripherally selective opioid mu receptor antagonist activity. Alvimopan is a selective and competitive antagonist at mu-opioid...		Opioid Receptor
T4691	Asimadoline hydrochloride	EMD-61753 hydrochloride	Opioid Receptor
	Asimadoline hydrochloride (EMD-61753 hydrochloride) is a κ-opioid receptor agonist potentially for the treatment of pruritus. Asimadoline hydrochloride has also been shown to be used in the treatment of irritable bowel s...		Opioid Receptor
T79430	μ opioid receptor agonist 3		Opioid Receptor
	Compound 20, identified as μ opioid receptor agonist 3, is a potent µOR agonist that exhibits an EC50 value of 0.87 nM. It holds promise for research into pain management and neuropsychiatric disorders [1].		Opioid Receptor
T62025	μ opioid receptor agonist 2
	μ opioid receptor agonist 2 （Compound H-3）is a MOR receptor agonist. μ opioid receptor agonist 2 can be used for the research of pain and pain related diseases.
T62268	μ opioid receptor agonist 1
	μ opioid receptor agonist 1 (Compound H-1a) is an optically pure oxyheterocyclic substituted pyrroloxypyrazole derivative and an MOR receptor agonist that can be used in the study of pain and pain-related disorders.
T61901	σ1 Receptor/μ Opioid receptor modulator 1
	σ 1 Receptor/ μ Opioid receiver modulator 1 (Compound 44) is an effective σ 1 receptor antagonist (Ki=1.86 nM) and μ Opioid receptor agonists (Ki=2.1 nM). Opioid receptor modulator 1 shows potent analgesic activity, and ...
T4633	Asimadoline	EMD-61753	Opioid Receptor
	Asimadoline (EMD-61753) is a proprietary small molecule therapeutic, originally discovered by Merck KGaA of Darmstadt, Germany. Asimadoline was originally developed to treat peripheral pain such as arthritis. Asimadoline...		Opioid Receptor
T7567L	Adrenorphin 3TFA(88377-68-8(free base))	Metorphamide	Opioid Receptor
	Adrenorphin 3TFA(88377-68-8(free base)) (Metorphamide) is an agonist of μ-opioid receptor(Ki :12 nM).		Opioid Receptor
T4386	PZM21		Opioid Receptor
	PZM21 is an effective and selective μ opioid receptor agonist (EC50: 1.8 nM).		Opioid Receptor
T23002	ML-335		Opioid Receptor
	ML-335 is a μ-δ isomer-targeted agonist, a μOR-δOR-biased ligand that can serve as a scaffold for the development of unique types of (isomer-biased) drugs.ML-335 is a MOR (μ-opioid receptor)/DOR (δ-opioid receptor) heter...		Opioid Receptor
T7173L	[Leu5]-Enkephalin acetate(58822-25-6 free base)	Leucine enkephalin,Leu-enkephalin,Leucyl-enkephalin	Opioid Receptor , Endogenous Metabolite
	[Leu5]-Enkephalin acetate(58822-25-6 free base) is an endogenous neuropeptide involved in nociception and an agonist of δ-opioid and μ-opioid receptors (Kis = 4.0 and 3.4 nM, respectively)		Opioid Receptor , Endogenous Metabolite
TP1832	Gluten Exorphin C		Opioid Receptor
	Gluten exorphin C is an opioid peptide derived from wheat gluten. Its IC50 values are 40 μM and 13.5 μM for μ opioid and δ opioid activities in the GPI and MVD assays, respectively.Gluten Exorphin C, isolated from the pe...		Opioid Receptor
T6175	ADL-5859	ADL5859 Hydrochloride,ADL5859 HCl	Opioid Receptor
	ADL-5859 (ADL5859 Hydrochloride) is a selective δ-opioid receptor agonist ( Ki: 0.8 nM), selectivity against opioid receptor κ, μ, and little inhibition for the hERG channel.		Opioid Receptor
T5167	Cebranopadol	GRT6005	Opioid Receptor
	Cebranopadol (GRT6005) is an analgesic NOP and opioid receptor agonist with Kis of 0.9 nM, 0.7 nM, 2.6 nM, 18 nM for human NOP, μ-opioid (MOP), κ-opioid (KOP) and δ-opioid (DOP) receptor, respectively.		Opioid Receptor
T39284	EST73502 HCl		Opioid Receptor
	EST73502 is an agonist of μ-opioid receptor(Ki = 64 nM) agonist and an antagonist of σ1 receptor (Ki = 118 nM). EST73502 displays antinociceptive activity.		Opioid Receptor
T4407	SR17018		Opioid Receptor
	SR17018 is an mu-opioid-receptor (MOR) agonist, binding with GTPγS, with an EC50 of 97 nM.		Opioid Receptor
T14551	Bevenopran	CB-5945,ADL-5945	Opioid Receptor
	Bevenopran (CB-5945) is a peripheral antagonist of μ-opioid receptor and can be used in studies about the treatment of opioid-induced bowel dysfunction.		Opioid Receptor
T67888L	Samidorphan HCl	Samidorphan HCl（852626-89-2 free base）	Opioid Receptor
	Samidorphan HCl is an orally active and highly potent modulator of the opioid system that binds to μ‐opioid, κ‐opioid, and delta-opioid receptors. Samidorphan HCl is a novel μ-opioid receptor antagonist, a partial agonis...		Opioid Receptor