Powder: -20°C for 3 years | In solvent: -80°C for 1 year
SR17018 is an mu-opioid-receptor (MOR) agonist, binding with GTPγS, with an EC50 of 97 nM.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | In stock | $ 64.00 | |
10 mg | In stock | $ 97.00 | |
25 mg | In stock | $ 213.00 | |
50 mg | In stock | $ 347.00 | |
100 mg | In stock | $ 563.00 | |
200 mg | In stock | $ 786.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 70.00 |
Description | SR17018 is an mu-opioid-receptor (MOR) agonist, binding with GTPγS, with an EC50 of 97 nM. |
Targets&IC50 | μ opioid receptor:NA |
In vitro | SR17018 acts as an agonist at the mu-opioid receptor (MOR), exhibiting binding affinity with GTPγS, demonstrated by an EC50 value of 97 nM. It does not significantly induce βarrestin2 recruitment to the MOR at concentrations below 10 μM, suggesting its mechanism of action primarily involves signaling through G proteins rather than βarrestin2 pathways. |
Molecular Weight | 410.72 |
Formula | C19H18Cl3N3O |
CAS No. | 2134602-45-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 4.11 mg/mL (10 mM), Sonification and heating are recommended.
You can also refer to dose conversion for different animals. More
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SR17018 2134602-45-0 Endocrinology/Hormones GPCR/G Protein Neuroscience Opioid Receptor SR 17018 SR-17018 inhibit Inhibitor inhibitor