ventral — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T23283	2-Methoxyidazoxan monohydrochloride	RX 821002 hydrochloride	Adrenergic Receptor
	L-Albizziin (2-Methoxyidazoxan monohydrochloride) is a highly potent selective antagonist of the alpha 2r adrenergic receptor, with little or no antagonistic effect on imidazoline. It has a significantly higher affinity ...		Adrenergic Receptor
T15239	Epristeride	SKF105657,ONO-9302	Apoptosis , Reductase
	Epristeride (ONO-9302) is an orally active, selective and non-competitive steroidal 5-α-reductase isoform 2 inhibitor that inhibits SR isoform 2.Episteride reduces prostate size and improves symptoms in men with BPH.Epis...		Apoptosis , Reductase
T24885L	Tiaspirone hydrochloride	BMY-13859 hydrochloride,Tiaspirone hydrochloride（87691-91-6 Free base)	Dopamine Receptor , 5-HT Receptor
	Tiaspirone hydrochloride (BMY-13859 hydrochloride) exhibits antipsychotic activity. Tiaspirone hydrochloride influences the electrophysiological activity of dopaminergic neurons in the substantia nigra zona compacta (A9 ...		Dopamine Receptor , 5-HT Receptor
TP1413L	Crustacean Cardioactive Peptide Acetate	CCAP acetate
	Crustacean Cardioactive Peptide Acetate (CCAP acetate) is is the most conserved and ubiquitous neuropeptide in arthropods and is produced in insects by a network of conserved neurons in the ventral nerve cord.Crustacean ...
T7218	Endomorphin 2		Opioid Receptor
	Endomorphins-2 (EM-2) could decrease both the frequency and amplitude of the sEPSC of the motoneurons in lamina IX, which was reversed by the MOR antagonist CTOP. EM-2-IR fibers originated from primary afferent fibers f...		Opioid Receptor
T76863	Elezanumab	AE12-1Y-QL,ABT-555	TGF-beta/Smad
	Elezanumab(ABT-555) is a potent human anti-RGMa monoclonal antibody.Elezanumab exerts its inhibitory effect on RGMa-mediated BMP signaling through the SMAD1/5/8 pathway, with an IC50 of approximately 97 pM.Elezanumab pro...		TGF-beta/Smad
T26495	AA560	AA 560,AA-560
	AA560 is a nonsteroidal antiandrogen. AA560 decreases the uptake of 3H-androgens in the ventral prostate and decreases the weight of accessory organs.
T31903	Galphimine B
	Galphimine B is a cyclodesiccated triterpenoid from Galphimia Glauca, which can regulate the synaptic transmission of dopaminergic ventral tegmental neurons and has a sedative effect.
TP2136	(d(CH2)51,Tyr(Me)2,Arg8)-Vasopressin
	Selective vasopressin V1A receptor antagonist. Inhibits vasopressin and oxytocin-induced increases in intracellular calcium concentrations in vitro (IC50 values are 5 and 30 nM respectively). Exhibits potent and prolonge...
T73272	VU6019650
	VU6019650 is a potent and selective orthosteric antagonist of M5 mAChR ( IC 50 =36 nM), can be used for opioid use disorder (OUD) relief. VU6019650 can cross blood brain barrier, potentially modulates the mesolimbic dopa...
T62706	RTI-7470-44
	RTI-7470-44 is a potent and selective human trace amine-associated receptor 1 (hTAAR1) antagonist (IC50: 8.4 nM) that crosses the blood-brain barrier. RTI-7470-44 increases the spontaneous firing rate of dopaminergic neu...
T36373	Urocortin II (mouse) (trifluoroacetate salt)
	Urocortin II is a neuropeptide hormone and member of the corticotropin-releasing factor (CRF) family which includes mammalian CRF , urocortin , urocortin III , frog sauvagine, and piscine urotensin I.1 Mouse urocortin II...
T37718	Galanin (rat, mouse) (trifluoroacetate salt)	GAL (rat, mouse),Galanin (rat, mouse) (trifluoroacetate salt)
	Galanin is a neuropeptide with diverse biological activities. [1][2][3][4][5] It binds to rat galanin (GAL) receptor subtypes GAL1-3 (IC50s = 0.339, 1.35, and 3.31 nM, respectively) and human GAL1-3 (IC50s = 0.288, 1.62,...