tuberculosis — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T38298	Tuberculosis inhibitor 3
	Tuberculosis inhibitor 3 (compound 2i) exhibits potent anti-TB properties (MIC < 0.016 μg/mL) against both drug-sensitive and resistant MTB strains, along with acceptable pharmacokinetic profiles and oral bioavailability...
T13223	Tuberculosis inhibitor 1		Others
	Tuberculosis inhibitor 1 is a potent and non-cytotoxic inhibitor of trypanosoma brucei growth (EC50: 5 nM).		Others
T62087	Tuberculosis inhibitor 4
	Tuberculosis inhibitor 4 (compound 16) is a spirothiazolidinone based on mandelic acid that exhibits potent antimycobacterial action. The inhibitor inhibited 98% of Mycobacterium tuberculosis strain H37Rv at concentratio...
T79510	Tuberculosis inhibitor 7
	Tuberculosis inhibitor 7 (compound 2d), a 3-methoxy-2-phenylimidazo[1,2-b]pyridazine derivative, exhibits potent activity against Mycobacterium tuberculosis and Mycobacterium marinum, with both displaying a MIC 90 of 0.6...
T80927	Tuberculosis inhibitor 10
	Tuberculosis Inhibitor 10 moderately inhibits the enzyme MSMEG_6649 and potentiates the antimycobacterial activity of PAS [1].
T38359	Dup-721		Antibacterial
	DuP-721 is a broad spectrum and orally active antibacterial agent. DuP-721 inhibits a variety of clinically susceptible and resistant bacteria, especially M. tuberculosis.		Antibacterial
T62086	Tuberculosis inhibitor 5
	Tuberculosis inhibitor 5 (Compound 11i) is a potent anti-tuberculosis agent with no apparent cytotoxicity. tuberculosis inhibitor 5 is an antimycobacterial biphenyl analogue.
T80925	Tuberculosis inhibitor 12
	Tuberculosis Inhibitor 12, an oxadiazole derivative, effectively inhibits Mycobacterium tuberculosis, demonstrating inhibition rates of 82% and 78% at a concentration of 20 μM on 7H9-Tw-OADC media, respectively [1].
T79511	Tuberculosis inhibitor 8
	Tuberculosis inhibitor 8 (compound 3b), a 3-methoxy-2-phenylimidazo[1,2-b]pyridazine derivative, exhibits potent activity against both Mycobacterium tuberculosis and Mycobacterium marinum with an MIC 90 of 0.69 μM [1].
T80926	Tuberculosis inhibitor 11
	Compound 14, also known as Tuberculosis Inhibitor 11, enhances the antimycobacterial efficacy of antitubercular agent [1].
T79509	Tuberculosis inhibitor 6
	Tuberculosis inhibitor 6 (compound 2c), a 3-methoxy-2-phenylimidazo[1,2-b]pyridazine derivative, is highly active against Mycobacterium tuberculosis (MIC 90 of ≤1.66 μM) and Mycobacterium marinum (MIC 90 of 2.65 μM) [1].
T79512	Tuberculosis inhibitor 9
	Tuberculosis inhibitor 9 (compound 3d), a 3-methoxy-2-phenylimidazo[1,2-b]pyridazine derivative, exhibits potent activity against Mycobacterium tuberculosis and Mycobacterium marinum, with an MIC 90 of 0.64 μM for both o...
T1426	Pyrazinamide	Pyrazinoic acid amide,Pyrazinecarboxamide	Antibacterial , Antibiotic , Autophagy , Fatty Acid Synthase
	Pyrazinamide (Pyrazinecarboxamide), an antimycobacterial, is utilized therapeutically as an antitubercular agent, which is a synthetic pyrazinoic acid amide derivative.
T9734	InhA-IN-2		CDK
	InhA-IN-2 directly inhibits InhA and does not require activation by the catalase peroxidase KatG.		CDK
T3582	BTZ043		Antibacterial , Antibiotic , DprE1
	BTZ043 is a DprE1 inhibitor with nanomolar bactericidal activity against Mycobacterium tuberculosis in vitro.		Antibacterial , Antibiotic , DprE1
T7342	BM212		Antibacterial
	BM212 is an antimycobacterial compound.It inhibits the growth of laboratory and clinical isolate M. tuberculosis strains.		Antibacterial
T4044	DprE1-IN-2		Antibacterial , DprE1
	DprE1-IN-2 is an effective DprE1 inhibitor.		Antibacterial , DprE1
T8411	C-215		Others
	C-215 is a novel inhibitor of mycobacterial membrane protein large 3 (MmpL3).		Others
T10411	AU1235		Antibacterial
	AU1235 is a Mycobacterium tuberculosis inhibitor.		Antibacterial
T8347	Rifamycin S		Reactive Oxygen Species , ROS , Antibacterial , Antibiotic
	Rifamycin S is a potent DNA-dependent RNA polymerase inhibitor,is a quinone and an antibiotic agnet against Gram-positive bacteria		Reactive Oxygen Species , ROS , Antibacterial , Antibiotic