sulfatase — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T81089	Steroid sulfatase-IN-7
	Steroid sulfatase-IN-7 is an irreversible inhibitor of steroid sulfatase (STS), demonstrating potent activity with an IC50 of 0.05 nM against human placental STS, rendering it suitable for application in cancer research ...
T62237	Steroid sulfatase-IN-4
	Steroid sulfatase-IN-4 (Compound 16) is an irreversible inhibitor of steroid sulfatase (STS) that acts on human STS (IC50: 25 nM). steroid sulfatase-IN-4 can be used to study endometriosis.
T61212	Steroid sulfatase-IN-2
	Steroid sulfatase-IN-2 is an active inhibitor of steroid sulfatase (STS), demonstrating an IC50 value of 109.5 nM. Its potential application lies in hormone-dependent cancer research, specifically estrogen-dependent brea...
T61686	Steroid sulfatase-IN-3
	Steroid sulfatase-IN-3 (compound 1q) is a highly effective Steroid sulfatase (STS) inhibitor, exhibiting an IC 50 value of 25.8 nM. This compound also demonstrates antiproliferative properties against T-47D estrogen-depe...
T81091	Steroid sulfatase-IN-5
	Steroid sulfatase-IN-5 (compound 10b), an inhibitor of steroid sulfatase (STS) with an IC50 of 0.32 nM, effectively suppresses T-47D breast cancer cell proliferation, demonstrating an IC50 value of 35.7 μM. This compound...
T61687	Steroid sulfatase-IN-1
	Steroid sulfatase-IN-1 is a highly potent and orally active inhibitor of the enzyme Steroid sulfatase, with an impressive IC50 value of 1.71 μM. This compound exhibits notable antitumor activity, achieving a TGI (tumor g...
T81090	Steroid sulfatase-IN-6
	Steroid Sulfatase-IN-6 (Compound 10c) serves as an irreversible steroid sulfatase (STS) inhibitor, exhibiting a K i value of 0.4 nM against human placenta STS, and is applicable in tumor disease research [1].
T61979	Steroid sulfatase/17β-HSD1-IN-4
	Steroid sulfatase/17β-HSD1-IN-4 (compound 37) is a potent dual inhibitor of steroid sulfatase ( STS ) and 17β-hydroxysteroid dehydrogenase type 1 ( 17β HSD1 ). Steroid sulfatase/17β-HSD1-IN-4 irreversibly inhibits hSTS a...
T62236	Steroid sulfatase/17β-HSD1-IN-3
	Steroid sulfatase/17β-HSD1-IN-3 (compound 19) is a dual inhibitor of steroid sulfatase (STS) and 17β-hydroxysteroid dehydrogenase type 1 (17β HSD1). Steroid sulfatase/17β-HSD1-IN-3 can be used to study endometriosis and ...
T61716	Steroid sulfatase/17β-HSD1-IN-1
	Steroid sulfatase/17β-HSD1-IN-1 is a highly effective inhibitor of both steroid sulfatase and 17β-hydroxysteroid dehydrogenase type 1 (17β-HSD1) activities, displaying an IC50 value of 28 nM against cellular human steroi...
T81092	Steroid sulfatase/17β-HSD1-IN-5
	Steroid sulfatase/17β-HSD1-IN-5 serves as an irreversible inhibitor of steroid sulfatase (STS) and a reversible, selective inhibitor of 7β-hydroxysteroid dehydrogenase type1 (17β-HSD1), exhibiting IC50 values of 43 nM fo...
T82477	Elosulfase alfa	Chondrosulfatase,Chondrosulfatases,BMN 110,Chondroitinase,Chondroitin sulfatase
	Elosulfase alfa (BMN 110), a recombinant human N-acetylgalactosamine-6-sulfatase (GALNS), serves as enzyme replacement therapy for mucopolysaccharidosis IVA (MPS IVA), commonly referred to as Morquio A syndrome [1].
T36857	Estrone sulfate sodium	Estrone 3-sulfate (sodium salt),17β-Estrone 3-sulfate	Endogenous Metabolite
	Estrone sulfate sodium (17β-Estrone 3-sulfate) is an endogenous steroid and an estrogen ester that is biologically inactive. It is converted by steroid sulfatase into estrone . Estrone sulfate sodium has been investigate...		Endogenous Metabolite
T76163	Arylsulfatase
	Arylsulfatase, a type I sulfatase enzyme found in both prokaryotes and eukaryotes, is frequently utilized in biochemical research [1].
T11235	Estradiol 3-sulfamate	ES-J 995,E2MATE,BLE 00084	Others
	.Estradiol 3-sulfamate inhibits estrone sulfatase with an IC50 of 251 nM and a Ki of 133 nM. Estradiol 3-sulfamate is a potent, long-acting, and orally active steroid sulfatase inhibitor.		Others
T4464	Irosustat	667-Coumate,BN83495,STX64	Others
	Irosustat (667-Coumate) is a potent steroid sulfatase inhibitor, with an IC50 of 8 nM, and exhibits anti-breast cancer activity.		Others
T15082	DDAO		Others
	DDAO is a promising near-infrared (NIR) red fluorescent probe with long emission wavelength (λem = 656 nm) and tunable excitation wavelength (600-650 nm). It can de desiged for detection of the activities of different en...		Others
T72470	Estrone O-sulfamate	Estrone 3-O-sulfamate	Others
	Estrone O-sulfamate (Estrone 3-O-sulfamate) is a potent inhibitor of steroid sulfatase (STS). Estrone O-sulfamate is a placental microsomal inhibitor (P.M.) with IC50 values of 18 nM. Estrone O-sulfamate showed inhibitor...		Others
T32138	Iduronate 2-sulfate
	Iduronate 2-sulfate is a sulfatase enzyme related to Hunter syndrome.
T83172	Adam-20-S
	Adam-20-S is a potent inhibitor of glucosinolate sulfatase, exhibiting an IC50 of 9.04 μg/mL. This compound disrupts glucosinolate metabolism, enhancing the production of toxic isothiocyanates in P. xylostella [1].