reactivator — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T24730	Roslin 2 bromide	Roslin-2,Benzylhexamethylenetetramine bromide,Roslin2	FAK , p53
	Roslin 2 bromide (Benzylhexamethylenetetramine bromide) is a p53 reactivator that disrupts the binding of FAK and p5. Roslin 2 bromide exhibits anticancer effects.		FAK , p53
T1111	Pralidoxime Chloride	2-PAM chloride,2-Pyridinealdoxime methochloride,2-PAM (chloride)	AChE
	Pralidoxime Chloride (2-PAM chloride) is a useful agent in the treatment of organophosphate poisoning. Pralidoxime binds to organophosphate-inactivated acetylcholinesterase, used to combat poisoning by organophosphates o...		AChE
T2464	ZMC1		p53
	NSC-319726 (ZMC1), a mutant p53R175 reactivator, suppresses growth of fibroblasts that expresses the p53R175 mutation (IC50 = 8 nM).		p53
T6954	PRIMA-1	2,2-Bis(hydroxymethyl)-3-quinuclidinone,NSC-281668,PRIMA 1	Apoptosis , Others , Ferroptosis , Autophagy
	PRIMA-1 (NSC-281668) is a mutant p53 reactivator. It induces apoptosis and inhibits growth of human tumors with mutant p53.		Apoptosis , Others , Ferroptosis , Autophagy
T70692	ST7612AA1		HIV Protease
	ST7612AA1 is a novel potent and oral HDCA inhibitor that acts as an HIV-1 latency reactivator. ST7612AA1 showed significant antitumor activity at low concentrations in vitro and in vivo. ST7612AA1 has potential anticance...		HIV Protease
T41068	P53R3		p53
	P53R3 is a potent reactivator of p53, effectively restoring sequence-specific DNA binding to several p53 hot spot mutants, namely p53 R175H, p53 R248W, and p53 R273H. This compound exhibits p53-dependent antiproliferativ...		p53
T27611	Ingenol 3-Hexanoate
	Ingenol 3-Hexanoate is a novel potent reactivator of latent HIV-1.
T70461	Pralidoxime mesylate
	Pralidoxime mesylate is a Cholinesterase Reactivator
T70236	Isonitrosoacetone
	Isonitrosoacetone is an acetylcholinesterase reactivator.
T68770	Obidoxime thiocyanate
	Obidoxime thiocyanate is an AChE reactivator.
T69271	Diethyxime
	Diethyxime is a a non-quaternarv Cholinesterase reactivator
T69079	Trimedoxime bromide
	Trimedoxime bromide is a cholinesterase reactivator used as an antidote in alkyl phosphate poisoning.
T21219	Isatin-O	Isatin-3-oxime
	Isatin-O acts as a neutral BBB crossing reactivator for acetylcholinesterase inhibited by paraoxon and is also an anticonvulsant.
T70641	Asoxime dimethanesulfonate
	Asoxime dimethanesulfonate is an oxime reactivator used for counteracting intoxication by nerve agents. It is able to reactivate acetylcholinesterase (AChE) inhibited by cytotoxic nerve agents such as sarin or soman.
T68624	Asoxime chloride monohydrate
	Asoxime chloride monohydrate is an oxime reactivator used for counteracting intoxication by nerve agents. It is able to reactivate acetylcholinesterase (AChE) inhibited by cytotoxic nerve agents such as sarin or soman.
T62857	K203
	K203 is a potent tabun-inhibited AChE reactivator and is an important antidote to organophosphorus poisoning.
T81998	K1833
	K1833 is an inhibitor and reactivator of human acetylcholinesterase (hrAChE), exhibiting an inhibition concentration (IC50) of 58$. Additionally, K1833 demonstrates potent inhibition (IC50 = 0.57$) and minimal reactivati...
T79013	SLMP53-2
	SLMP53-2 is a mutant p53 reactivator that restores the wild-type-like conformation and DNA-binding ability of mutp53-Y220C through enhanced interaction with Hsp70, thereby reinstating p53's transcriptional activity. This...