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Search Results for " pruritus "

15

Compounds

Cat No. Product Name Synonyms Targets
T7893 Bepotastine Bepotastine free base Others , Histamine Receptor
Bepotastine (Bepotastine free base) free base is a histamine 1 (H1) receptor antagonis.
T6405 Bepotastine Besilate Talion,TAU 284,Bepreve,Bepotastine Beslilate Histamine Receptor
Bepotastine Besilate (TAU 284) is a non-sedating and selective H1 receptor antagonist (pIC50: 5.7).
T0330 Diphenhydramine hydrochloride Diphenhydramine HCl,DPH Histamine Receptor
Diphenhydramine hydrochloride (DPH) is a histamine H1 antagonist used as an antitussive and antiemetic. It is also used for pruritus and dermatoses, for hypersensitivity reactions, as an antiparkinson, a hypnotic, and as...
T21472 Dimethindene maleate UNII-6LL60J9E0O,SU 6518,SU-6518 Histamine Receptor
Dimethindene maleate (SU 6518) is a histamine H1 antagonist and can be used in studies about the treatment of hypersensitivity reactions, pruritus and rhinitis.
TP1046 SLIGRL-NH2 Protease-Activated Receptor-2 Activating Peptide Protease-activated Receptor
SLIGRL-NH2 (Protease-Activated Receptor-2 Activating Peptide) is a protease-activated receptor-2 (PAR-2) agonist that induces non-histaminergic pruritus.
T4691 Asimadoline hydrochloride EMD-61753 hydrochloride Opioid Receptor
Asimadoline hydrochloride (EMD-61753 hydrochloride) is a κ-opioid receptor agonist potentially for the treatment of pruritus. Asimadoline hydrochloride has also been shown to be used in the treatment of irritable bowel s...
T0053 Hydroxyzine Pamoate Hydroxyzine embonate,Bobsule,Equipose Histamine Receptor
Hydroxyzine Pamoate (Bobsule) is a histamine H1 receptor antagonist that is effective in the treatment of chronic urticaria, dermatitis, and histamine-mediated pruritus. Unlike its major metabolite CETIRIZINE, it does ca...
T76724 Nemolizumab CIM331 Interleukin
Nemolizumab (CIM331) is a humanized monoclonal antibody against human interleukin-31 receptor A that inhibits the binding and subsequent signal transduction of interleukin-31 (IL-31) to its receptor. Nemolizumab can be u...
T2200 Hydroxyzine dihydrochloride Hydroxyzine 2HCl Histamine Receptor
Hydroxyzine dihydrochloride (Hydroxyzine 2HCl) is a histamine H1 receptor antagonist that is effective in the treatment of chronic urticaria, dermatitis, and histamine-mediated pruritus. Unlike its major metabolite CETIR...
T6529 Halobetasol propionate Halobetasol Propionate,Ulobetasol propionate,BMY-30056,CGP-14458 Phospholipase
Halobetasol propionate (BMY-30056) is the propionate salt form of halobetasol, a synthetic corticosteroid with anti-inflammatory, antipruritic, and vasoconstrictor activities. Halobetasol, a topical steroid, diffuses acr...
T0785L Dexchlorpheniramine free base Polaramine,Dexchlorpheniramine Maleate,Mylaramine
Dexchlorpheniramine Maleate, a histamine receptor antagonist, is used to treat urticaria, allergic rhinitis, allergic conjunctivitis and pruritus.
T38419 Difelikefalin CR-845,FE-202845
Difelikefalin (CR-845; FE-202845) is a peripherally restricted, selective agonist of the kappa opioid receptor (KOR). It exhibits anti-inflammatory properties and holds promise for modulating pruritus in conditions assoc...
T72520 GR 89696 free base
GR 89696 free base is a potent κ2 opioid receptor agonist with a high selectivity, offering potential benefits in pruritus prevention.
T62422 Nav1.8-IN-2
Nav1.8-IN-2 (compound 35A) is a potent inhibitor of Nav1.8 (IC50: 0.4 nM). Nav1.8-IN-2 can be used in studies of pain disorders, cough, acute and chronic pruritus.
T63965 Bepotastine tosylate
Bepotastine tosylate is a selective, orally active second-generation histamine H1 receptor antagonist that exhibits an inhibitory effect on histamine-mediated upregulation of nerve growth factor (NGF) expression. conjunc...
TargetMol