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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T7893 | Bepotastine | Bepotastine free base | Others , Histamine Receptor |
Bepotastine (Bepotastine free base) free base is a histamine 1 (H1) receptor antagonis. | |||
T6405 | Bepotastine Besilate | Talion,TAU 284,Bepreve,Bepotastine Beslilate | Histamine Receptor |
Bepotastine Besilate (TAU 284) is a non-sedating and selective H1 receptor antagonist (pIC50: 5.7). | |||
T0330 | Diphenhydramine hydrochloride | Diphenhydramine HCl,DPH | Histamine Receptor |
Diphenhydramine hydrochloride (DPH) is a histamine H1 antagonist used as an antitussive and antiemetic. It is also used for pruritus and dermatoses, for hypersensitivity reactions, as an antiparkinson, a hypnotic, and as... | |||
T21472 | Dimethindene maleate | UNII-6LL60J9E0O,SU 6518,SU-6518 | Histamine Receptor |
Dimethindene maleate (SU 6518) is a histamine H1 antagonist and can be used in studies about the treatment of hypersensitivity reactions, pruritus and rhinitis. | |||
TP1046 | SLIGRL-NH2 | Protease-Activated Receptor-2 Activating Peptide | Protease-activated Receptor |
SLIGRL-NH2 (Protease-Activated Receptor-2 Activating Peptide) is a protease-activated receptor-2 (PAR-2) agonist that induces non-histaminergic pruritus. | |||
T4691 | Asimadoline hydrochloride | EMD-61753 hydrochloride | Opioid Receptor |
Asimadoline hydrochloride (EMD-61753 hydrochloride) is a κ-opioid receptor agonist potentially for the treatment of pruritus. Asimadoline hydrochloride has also been shown to be used in the treatment of irritable bowel s... | |||
T0053 | Hydroxyzine Pamoate | Hydroxyzine embonate,Bobsule,Equipose | Histamine Receptor |
Hydroxyzine Pamoate (Bobsule) is a histamine H1 receptor antagonist that is effective in the treatment of chronic urticaria, dermatitis, and histamine-mediated pruritus. Unlike its major metabolite CETIRIZINE, it does ca... | |||
T76724 | Nemolizumab | CIM331 | Interleukin |
Nemolizumab (CIM331) is a humanized monoclonal antibody against human interleukin-31 receptor A that inhibits the binding and subsequent signal transduction of interleukin-31 (IL-31) to its receptor. Nemolizumab can be u... | |||
T2200 | Hydroxyzine dihydrochloride | Hydroxyzine 2HCl | Histamine Receptor |
Hydroxyzine dihydrochloride (Hydroxyzine 2HCl) is a histamine H1 receptor antagonist that is effective in the treatment of chronic urticaria, dermatitis, and histamine-mediated pruritus. Unlike its major metabolite CETIR... | |||
T6529 | Halobetasol propionate | Halobetasol Propionate,Ulobetasol propionate,BMY-30056,CGP-14458 | Phospholipase |
Halobetasol propionate (BMY-30056) is the propionate salt form of halobetasol, a synthetic corticosteroid with anti-inflammatory, antipruritic, and vasoconstrictor activities. Halobetasol, a topical steroid, diffuses acr... | |||
T0785L | Dexchlorpheniramine free base | Polaramine,Dexchlorpheniramine Maleate,Mylaramine | |
Dexchlorpheniramine Maleate, a histamine receptor antagonist, is used to treat urticaria, allergic rhinitis, allergic conjunctivitis and pruritus. | |||
T38419 | Difelikefalin | CR-845,FE-202845 | |
Difelikefalin (CR-845; FE-202845) is a peripherally restricted, selective agonist of the kappa opioid receptor (KOR). It exhibits anti-inflammatory properties and holds promise for modulating pruritus in conditions assoc... | |||
T72520 | GR 89696 free base | ||
GR 89696 free base is a potent κ2 opioid receptor agonist with a high selectivity, offering potential benefits in pruritus prevention. | |||
T62422 | Nav1.8-IN-2 | ||
Nav1.8-IN-2 (compound 35A) is a potent inhibitor of Nav1.8 (IC50: 0.4 nM). Nav1.8-IN-2 can be used in studies of pain disorders, cough, acute and chronic pruritus. | |||
T63965 | Bepotastine tosylate | ||
Bepotastine tosylate is a selective, orally active second-generation histamine H1 receptor antagonist that exhibits an inhibitory effect on histamine-mediated upregulation of nerve growth factor (NGF) expression. conjunc... |