20
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T25492 | Hepln-13 | Hepln 13,Hepln13 | c-Met/HGFR |
Hepln-13 is a hepsin inhibitor that acts by hindering prostate cancer bone metastasis. | |||
T73552 | BPDA2 | ||
BPDA2 is a highly selective and competitive SHP2 inhibitor, exhibiting IC50 values of 92.0 nM for SHP2, and 33.39 μM and 40.71 μM for SHP1 and SHP1B, respectively. This compound effectively downregulates mitogenic and ce... | |||
T17228 | Sabizabulin | ABI-231,VERU-111 | Microtubule Associated |
Sabizabulin (ABI-231) is an effective and orally bioavailable inhibitor of α and β tubulin against panels of melanoma and prostate cancer cell lines. Sabizabulin inhibits tumor growth and metastatic phenotypes of cervica... | |||
T28138 | NCDM-32B | NCDM 32B,NCDM32B | |
NCDM-32B, a novel potent and selective KDM4 inhibitor, impairs viability and transforms phenotypes of basal breast cancer. | |||
T34706 | SRI-29132 | SRI29132,SRI 29132,TPZ-11,TPZ 11,TPZ11 | |
SRI-29132 is potent; highly permeant of the blood-brain barrier; and selective for LRRK2 kinase activity, therefore effective in attenuating pro-inflammatory responses in macrophages and in rescuing neurite retraction ph... | |||
T71845 | Lockdown | ||
Lockdown is a reversible and non-competitive PPM1F inhibitor. Lockdown is selective for PPM1F, because this compound does not inhibit other protein phosphatases in vitro and does not induce additional phenotypes in PPM1F... | |||
T40950 | A3334 | ||
A3051, is a robust and orally active inhibitor of CXXC5-DVL with an IC 50 of 63.06 nM. Its applications include research into phenotypes associated with obesity, diabetes, and NASH that are induced by high fat diet (HFD)... | |||
T39586 | Cantrixil | TRX-E-002-1 | |
Cantrixil (TRX-E-002-1) is a second-generation super-benzopyran (SBP) compound, derived from TRX-E-002. It elicits an increase in phosphorylated c-Jun levels, leading to caspase-mediated apoptosis in ovarian cancer cells... | |||
T11219 | Equisetin | Others | |
Equisetin, an N-methylserine-derived acyl tetramic acid isolated from the terrestrial fungus Fusarium equiseti NRRL 5537, functions as a Quorum-sensing inhibitor (QSI) that specifically attenuates QS-regulated virulence ... | |||
T70138 | AZ0108 | ||
AZ0108 is an orally bioavailable, potent PARP1,2,6 inhibitor that potently inhibits centrosome clustering and is suitable for in vivo efficacy and tolerability studies. AZ0108 has been utilized as in vitro tools and in ... | |||
T10607 | BRD5631 | Autophagy | |
BRD5631 is an autophagy enhancer, enhances autophagy through an mTOR-independent pathway. BRD5631 affects several cellular disease phenotypes previously linked to autophagy, including protein aggregation, cell survival, ... | |||
T37745 | N-pentadecanoyl-L-Homoserine lactone | ||
Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density. This regulatory process manifests itself with a variety of phenotypes including biofilm forma... | |||
T37737 | N-cis-octadec-9Z-enoyl-L-Homoserine lactone | ||
Quorum sensing is a regulatory process used by bacteria for controlling gene expression in response to increasing cell density. This regulatory process manifests itself with a variety of phenotypes including biofilm form... | |||
T37879 | N-undecanoyl-L-Homoserine lactone | ||
Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density. This regulatory process manifests itself with a variety of phenotypes including biofilm forma... | |||
T37738 | N-cis-tetradec-9Z-enoyl-L-Homoserine lactone | ||
Quorum sensing is a regulatory process used by bacteria for controlling gene expression in response to increasing cell density. This regulatory process manifests itself with a variety of phenotypes including biofilm form... | |||
T37336 | N-3-oxo-hexadec-11(Z)-enoyl-L-Homoserine lactone | ||
Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density. This regulatory process manifests itself with a variety of phenotypes including biofilm forma... | |||
T37878 | N-tridecanoyl-L-Homoserine lactone | ||
Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density. This regulatory process manifests itself with a variety of phenotypes including biofilm forma... | |||
T37743 | N-octadecanoyl-L-Homoserine lactone | ||
Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density. This regulatory process manifests itself with a variety of phenotypes including biofilm forma... | |||
T37736 | N-cis-hexadec-9Z-enoyl-L-Homoserine lactone | N-(2-oxotetrahydrofuran-3S-yl) Palmitoleyl Amide,N-cis-hexadec-9Z-enoyl-L-Homoserine lactone | |
Quorum sensing is a regulatory process used by bacteria for controlling gene expression in response to increasing cell density.[1] This regulatory process manifests itself with a variety of phenotypes including biofilm f... | |||
T37741 | N-hexadecanoyl-L-Homoserine lactone | C16-HSL,N-palmitoyl-L-Homoserine,N-hexadecanoyl-L-Homoserine lactone | |
Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density.[1] This regulatory process manifests itself with a variety of phenotypes including biofilm fo... |