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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T9072 | Tuxobertinib | BDTX-189 | EGFR , HER , BTK , RIP kinase |
Tuxobertinib (BDTX-189) is a potent and selective inhibitor of allosteric EGFR and HER2 oncogenic mutations(KDs of 0.2, 0.76, 13 and 1.2 nM for EGFR, HER2, BLK and RIPK2, reapectively). BDTX-189 exhibits anticancer activ... | |||
T64124 | Sunvozertinib | DZD9008,DZD 9008,DZD-9008 | EGFR , BTK |
Sunvozertinib (DZD9008) is a potent ErbBs and BTK inhibitor and has inhibitory effects on EGFR, Her2 and mutant epidermal growth factor. Sunvozertinib showed inhibition of EGFR exon 20 NPH insertion, EGFR exon 20 ASV ins... | |||
T35901 | EGFR-IN-99 | JBJ-03-142-02 | EGFR , HER |
EGFR-IN-99 (JBJ-03-142-02) is an EGFR and HER2 Exon 20 insertion mutation inhibitor with antiproliferative activity for the study of non-small cell lung cancer (NSCLC). | |||
T31932 | GJ071 oxalate | GJ 071,GJ-071,GJ071 | Others |
GJ071 oxalate is a Nonsense suppressor. Nonsense suppressors (NonSups) induce “readthrough”, i.e., the selection of near cognate tRNAs at premature termination codons and insertion of the corresponding amino acid into na... | |||
T31011 | Coralyne chloride | Topoisomerase | |
Coralyne chloride is a protoberberine with strong anticancer activity. It can be used to prepare Coralyne derivatives, a fluorescent DNA-based molecular rectifier built into DNA duplexes through site-specific insertion. ... | |||
TP1573L | CLIP 86-100 acetate(648881-58-7 free base) | Others | |
CLIP 86-100 acetate(648881-58-7 free base) is amino acids 86 to 100 fragment of class II-associated invariant chain peptide called CLIP. The major histocompatibility complex class II molecule displays peptide fragments o... | |||
T9304 | (S)-Sunvozertinib | N-[5-[[4-[5-Chloro-4-fluoro-2-(2-hydroxypropan-2-yl)anilino]pyrimidin-2-yl]amino]-2-[(3S)-3-(dimethylamino)pyrrolidin-1-yl]-4-methoxyphenyl]prop-2-enamide,DZD9008 | EGFR , HER |
(S)-Sunvozertinib (DZD9008) is a rationally designed selective, irreversible EGFR/HER2 inhibitor. | |||
T31933 | GJ072 | GJ-072,GJ 072 | |
GJ-072 is a Nonsense suppressor. Nonsense suppressors (NonSups) induce “readthrough”, i.e., the selection of near cognate tRNAs at premature termination codons and insertion of the corresponding amino acid into nascent p... | |||
T71991 | PUN-96956 | ||
PUN-96956 is a novel BAM complex inhibitor, interfering with BamA-related processes and affect folding and insertion of OMPs. This product has no formal name. For the convenience of scientific communication, we named it ... | |||
T63792 | LDC0496 | ||
LDC0496 is a potent inhibitor of EGFR. LDC0496 significantly inhibits EGFR and Her2 exon 20 insertion mutations, and is selective for wild-type EGFR and kinase within the kinome. | |||
TP1573 | CLIP (86-100) | CLIP 86-100 | |
CLIP (86-100) is amino acids 86 to 100 fragment of class II-associated invariant chain peptide called CLIP. The major histocompatibility complex class II molecule displays peptide fragments of foreign proteins to trigger... | |||
T37862 | 9(R)-HODE | ||
9(R)-HODE is one of several monohydroxylated products of linoleic acid. All known mammalian lipoxygenases appear to catalyze the oxygenation of arachidonic and linoleic acid to give products having strictly the (S) confi... | |||
T69498 | DBPR112 HCl | ||
DBPR112 is a potent EGFR inhibitor (IC50=487 nM) as a Clinical Candidate for the Treatment of Non-Small Cell Lung Cancer. DBPR112), DBPR112 not only displayed a potent inhibitory activity against EGFRL858R/T790M double ... | |||
T60997 | GL0388 | ||
GL0388 is a Bax activator and leads to Bax insertion into mitochondrial membrane that induce Bax-mediated apoptosis. GL0388 inhibits tumor growth of breast cancer xenograft in vivo which also exhibits antiproliferative a... | |||
T63573 | WF-47-JS03 | ||
WF-47-JS03 is a selective and potent inhibitor of RET kinase that crosses the blood-brain barrier and is more than 500-fold more selective for the kinase insertion domain receptor (KDR).WF-47-JS03 acts on Ba/F3 cells tra... | |||
T38356 | 1,2-Dipalmitoyl-13C-sn-glycero-3-PC | ||
1,2-Dipalmitoyl-13C-sn-glycero-3-PC is intended for use as an internal standard for the quantification of 1,2-dipalmitoyl-sn-glycero-3-PC by GC- or LC-MS. 1,2-Dipalmitoyl-sn-glycero-3-PC (DPPC) is a zwitterionic glycerop... |