hypothalamus — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T1997	JNJ-31020028	JNJ 31020028	Neuropeptide Y Receptor
	JNJ-31020028 is a selective brain penetrant antagonist of neuropeptide Y2 receptor with high affinity(pIC50=8.07, human; pIC50=8.22, rat); it exhibits >100-fold selectivity for Y2 versus human Y1/Y4/Y5 receptors.		Neuropeptide Y Receptor
T20332L	Bam 12P acetate	Bam 12P acetate(75513-71-2 Free base)	Endogenous Metabolite
	Bam 12P acetate is the putative enkephalin precursor in bovine adrenal, pituitary, and hypothalamus.		Endogenous Metabolite
T83651	AC-263093		Neuropeptide Y Receptor
	AC-263093 is an NPFFR2 agonist with anxiolytic activity that increases c-Fos protein expression in the paraventricular nucleus of the hypothalamus.		Neuropeptide Y Receptor
T9857L	Vasopressin acetate	Vasopressin acetate (11000-17-2 Free base)	Endogenous Metabolite
	Vasopressin acetate, a cyclic nonapeptide, is synthesized centrally in the hypothalamus. Vasopressin acetate acts as a neurotransmitter, exerting its action by binding to specific G protein-coupled receptors.		Endogenous Metabolite
TP1104L	Melanin Concentrating Hormone, salmon acetate	MCH (salmon),Melanin Concentrating Hormone, salmon acetate(87218-84-6 free base)	Others , Melanin-concentrating Hormone Receptor (MCHR)
	Melanin Concentrating Hormone, salmon acetate (MCH (salmon)) is a 19 amino acid cyclic peptide, is largely expressed in the hypothalamus.		Others , Melanin-concentrating Hormone Receptor (MCHR)
TP1070L	PACAP (1-27), human, ovine, rat acetate	PACAP 1-27 acetate,PACAP (1-27), human, ovine, rat acetate(127317-03-7 free base)	PACAP
	PACAP (1-27), human, ovine, rat acetate (PACAP 1-27 acetate) is a novel neuropeptides originally isolated from bovine hypothalamus, also found in humans and rats.		PACAP
TP1112L	LH-RH, salmon acetate(86073-88-3 free base)	Luteinizing Hormone Releasing Hormone (LH-RH), salmon acetate	Others
	LH-RH, salmon acetate(86073-88-3 free base) (Luteinizing Hormone Releasing Hormone (LH-RH), salmon acetate) is a pituitary Hormone synthesized in the hypothalamus and plays a crucial role in the control of reproductive f...		Others
T38193L	β-Endorphin (1-27) (human) acetate	β-Endorphin (1-27) (human) acetate(76622-84-9 Free base)	Opioid Receptor
	β-Endorphin (1-27) (human) acetate, existing in the hypophysis cerebri and hypothalamus, exhibits antinociception activity. β-Endorphin (1-27) (human) acetate is an agonist of opioid receptor, showing preferred affinity ...		Opioid Receptor
TP2015L	HS 014 acetate(207678-81-7 free base)		Melanocortin Receptor
	HS 014 acetate is a potent and selective melanocortin MC4 receptor antagonist (Ki values are 3.16, 108, 54.4 and 694 nM for cloned human MC4, MC1, MC3 and MC5 receptors respectively). Increases food intake in rats and no...		Melanocortin Receptor
T15368L	Galantide acetate	Galantide acetate(138579-66-5 Free base)	Neuropeptide Y Receptor
	Galantide acetate, a non-specific galanin receptor antagonist, is a peptide consisting of fragments of galanin and substance P. Galantide acetate recognizes two classes of galanin binding sites (KD<0.1 nM and ~6 nM) in t...		Neuropeptide Y Receptor
TP1104	Melanin Concentrating Hormone, salmon	MCH (salmon)
	Melanin Concentrating Hormone (MCH), a 19 amino acid cyclic peptide, is largely expressed in the hypothalamus.
T20403	Dynorphin A (1-8)	PH-8P,Dynorphin (1-8)
	Dynorphin (1-8) is an opioid octapeptide from the porcine hypothalamus. It comprises the N-terminal eight residues of dynorphin.
TP1950	PEN(mouse)	PEN (mouse)
	Endogenous peptide GPR83 agonist. ProSAAS-derived neuropeptide. Activates phospholipase C (PLC)-mediated signaling cascade in mouse hypothalamus.
TP1342	GnRH-I
	GnRH-I is a small 10 amino acid long peptide (decapeptide) from the hypothalamus,It is also known as luteinizing hormone releasing hormone (LHRH), is a key molecule in the regulation of reproduction in vertebrates. GnRH,...
T37478	Acetyl β-Endorphin (1-26) (human) (trifluoroacetate salt)
	Acetyl β-endorphin (1-26) is a neuropeptide found in rat hippocampus, brain stem, and pituitary. It is also present in the human hypothalamus, where it comprises approximately 4.9% of total β-endorphin peptides. Acetyl β...
T13433	β-Endorphin, human		Others
	β-Endorphin, human, a prominent endogenous peptide, existing in the hypophysis cerebri and hypothalamus,and is an agonist of opioid receptor.		Others
TP1649	Urocortin III, mouse
	Mouse UcnIII is expressed predominantly in regions of the brain known to be involved in stress-related behaviours, and its expression in the hypothalamus increases following restraint.
TP1070	PACAP (1-27), human, ovine, rat	PACAP 1-27
	PACAP (1-27) (the N-terminal fragment of PACAP-38) is a novel neuropeptides originally isolated from bovine hypothalamus, also found in humans and rats.
TP1112	Luteinizing Hormone Releasing Hormone (LH-RH), salmon	LH-RH, salmon
	Luteinizing Hormone Releasing Hormone (LH-RH) is a pituitary Hormone synthesized in the hypothalamus and plays a crucial role in the control of reproductive function.
T80116	LHRH		GNRH Receptor
	Luteinizing hormone-releasing hormone (LHRH) is a neuropeptide produced in the hypothalamus that plays a pivotal role in regulating reproduction and has applications in cancer research [1].		GNRH Receptor