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Search Results for " epigenetics "

10

Compounds

Cat No. Product Name Synonyms Targets
T7900 BAY-474 c-Met/HGFR
BAY-474 is an inhibitor of tyrosine-protein kinase c-Met. It acts as an epigenetics probe
T3624 A-366 A 366,A366 Epigenetic Reader Domain , Histone Methyltransferase
A-366 is a highly selective peptide-competitive histone methyltransferase G9a inhibitor with IC50s of 3.3 and 38 nM for G9a and GLP, respectively.It is more than 1,000-fold selective for G9a and GLP over the other 21 met...
T15784 LP99 Epigenetic Reader Domain
LP99 is an epigenetic probe. LP99 disrupts the binding of BRD7 and BRD9 to chromatin in cells. LP99 is an effective and selective inhibitor of the BRD7 and BRD9 bromodomains (Kd: 99 nM against BRD9).
T1972 GSK-5959 Epigenetic Reader Domain
GSK-5959 is an effective, specific and cell permeable BRPF1 bromodomain inhibitor (IC50: ~80 nM). The selectivity of GSK-5959 for BRPF1 is >100-fold over a panel of 35 other bromodomains, including BRPF2/3 and BET family...
T5198 Bobcat339 Bobcat339 hydrochloride DNA Methyltransferase
Bobcat339 is a novel cytosine-based TET enzyme inhibitor (IC50s: 33/73 uM for TET1/2), but not DNMT3a, does not inhibit the DNA methyltransferase DNMT3a.
T6879 LLY-507 LLY507,LLY 507 Histone Methyltransferase
LLY-507 is an effective, cell-active, and specific inhibitor of protein-lysine Methyltransferase SMYD2.
T7194 CM-272 Apoptosis , DNA Methyltransferase , Histone Methyltransferase
CM-272 is a dual G9a/DNA methyltransferases (DNMTs) inhibitor.
T17143 Toyocamycin Vengicide Apoptosis , Others , IRE1 , Antibiotic , Antifungal
Toyocamycin (Vengicide) is an adenosine analog produced by Actinomycete, acts as an XBP1 inhibitor, inhibits IRE1α-induced ATP-dependent XBP1 mRNA cleavage (IC50: 80 nM). Toyocamycin induces apoptosis.
T79131 KAT modulator-1 Histone Acetyltransferase
KAT modulator-1 (Compound 3), an epigenetics research tool, selectively interacts with the full-length p300 protein but not its catalytic domain [1].
T61012 Bobcat339 hydrochloride
Bobcat339 hydrochloride can be used in the field of epigenetics and as a starting point for new therapeutics targeting DNA methylation and gene transcription. Bobcat339 hydrochloride is a potent and selective cytosine-ba...
TargetMol