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Search Results for " colchicine "

20

Compounds

Cat No. Product Name Synonyms Targets
T0320 Colchicine Colcin,Colchineos,Colchisol Apoptosis , Microtubule Associated , Autophagy
Colchicine (Colcin) is a natural product that is an inhibitor of microtubule polymerization (IC50=3 nM) and blocks microtubule polymerization by binding to microtubule proteins. Colchicine can be used in the treatment of...
T30999 Colchicine, deacetamido-5,6-didehydro- Deacetamido-6-dehydrocolchicine,Colchicine,deacetamido-6-dehydro- (7CI)
Colchicine, deacetamido-5,6-didehydro- is a biochemical.
T31000 Colchicine, N-deacetyl-10-thio- N-Deacetylthiocolchicine,Desacetyl thiocolchicine,Deacetylthiocolchicine
Colchicine, N-deacetyl-10-thio- is a biochemical.
T41248 Thiocolchicine Microtubule Associated
Thiocolchicine is an effective inhibitor of tubulin polymerization with an IC50 of 2.5 µM and a Ki of 0.7 µM. Thiocolchicine induces cell apoptosis. Thiocolchicine can be used as an ADC cytotoxin in ADC technology.
T9812 Tubulin inhibitor 24 Microtubule Associated
Tubulin inhibitor 24 is a potent inhibitor that can inhibit tubulin polymerization.
TN6706 3-demethylcolchicine Reactive Oxygen Species
3-demethylcolchicine is a natural product isolated from Gloriosa superba.Inhibitory effect on the polymerization of purified bovine brain tubulin.
T15012 Crolibulin EPC2407 Microtubule Associated
Crolibulin (EPC2407) is an inhibitor of small molecule tubulin polymerization.
T31906 Gamma-Lumicolchicine
gamma-Lumicolchicine is three, alpha, beta, and gamma isomers of ultraviolet degradation products of colchicine that lack many of the physiological actions of the parent; used as experimental control for colchicine actio...
T32946 Lumicolchicine
Lumicolchicine is a bioactive chemical.
T31244 Deacetylisocolchicine
Deacetylisocolchicine is a biochemical.
T31255 Deacetylthiocolchicine hydrochloride Deacetylthiocolchicine chlorhydrate,Deacetylthiocolchicine HCl
Deacetylthiocolchicine hydrochloride is a biochemical.
T72544 4-Formylcolchicine
4-Formylcolchicine, a potent anticancer agent, demonstrates cytotoxicity with IC 50 values of 1.007 µM for A549 cells, 0.128 µM for HT-29 cells, and 0.054 µM for HCT116 cells.
TN7063 N-Acetaminophen NSC 403155,N-Acetyldemecolcine,N-Methylcolchicine,N-Acetylcolchamine Others
N-Acetaminophen (N-Methylcolchicine) is a methylated form of Colchicine.
T77647 Tubulin polymerization-IN-43 Apoptosis , Microtubule Associated
Tubulin polymerization-IN-43 is an inhibitor of tubulin polymerisation.Tubulin polymerization-IN-43 has multiple effects, disrupting the cellular microtubule network by targeting the colchicine locus and promoting cell c...
T60009 YS-370 P-gp
YS-370 is an orally active inhibitor of P-gp and shows moderate inhibition against CYP3A4. YS-370 effectively reverses multidrug resistance to paclitaxel and colchicine and exhibits stronger antitumor activity in combina...
T67935 Tubulin inhibitor 11 Apoptosis , Microtubule Associated
Tubulin Inhibitor 11 is a potent, orally active agent that inhibits tubulin by targeting the Colchicine binding site. It impedes tubulin polymerization, leading to mitotic blockade and apoptosis.
T9595 LP-261 Microtubule Associated
LP-261 is a novel tubulin targeting anticancer agent that binds at the colchicine site on tubulin, inducing G2/M arrest.
T28886 Suprafenacine N'-[(E)-(4-methylphenyl)methylidene]-4,5,6,7-tetrahydro-1H-indazole-3-carbohydrazide Microtubule Associated
Suprafenacine (N'-[(E)-(4-methylphenyl)methylidene]-4,5,6,7-tetrahydro-1H-indazole-3-carbohydrazide) is a cell-permeable microtubule destabilizer that induces cell cycle arrest and apoptosis in G2/M phase. Suprafenacine ...
T65128 Tartaric acid disodium dihydrate Disodium L-(+)-Tartrate Dihydrate Phosphatase , Endogenous Metabolite
Tartaric acid disodium dihydrate (Disodium L-(+)-Tartrate Dihydrate) is commonly used as a buffer in molecular biology and cell culture.Tartaric acid disodium dihydrate is an acid phosphatase inhibitor that increases the...
T2511 Plinabulin NPI-2358 Microtubule Associated
Plinabulin (NPI-2358) (NPI-2358) is a vascular disrupting agent (VDA) against tubulin-depolymerizing tumor cells ( IC50: 9.8-18 nM). Plinabulin selectively targets and binds to the colchicine-binding site of tubulin, the...

Compounds

Colchicine
T0320
Synonym: Colcin,Colchineos,Colchisol
Target: Apoptosis, Microtubule Associated, Autophagy
Colchicine, deacetamido-5,6-didehydro-
T30999
Synonym: Deacetamido-6-dehydrocolchicine,Colchicine,deacetamido-6-dehydro- (7CI)
Target:
Colchicine, N-deacetyl-10-thio-
T31000
Synonym: N-Deacetylthiocolchicine,Desacetyl thiocolchicine,Deacetylthiocolchicine
Target:
Thiocolchicine
T41248
Synonym:
Target: Microtubule Associated
Tubulin inhibitor 24
T9812
Synonym:
Target: Microtubule Associated
3-demethylcolchicine
TN6706
Synonym:
Target: Reactive Oxygen Species
Crolibulin
T15012
Synonym: EPC2407
Target: Microtubule Associated
gamma-Lumicolchicine
T31906
Synonym:
Target:
Lumicolchicine
T32946
Synonym:
Target:
Deacetylisocolchicine
T31244
Synonym:
Target:
Deacetylthiocolchicine hydrochloride
T31255
Synonym: Deacetylthiocolchicine chlorhydrate,Deacetylthiocolchicine HCl
Target:
4-Formylcolchicine
T72544
Synonym:
Target:
N-Acetaminophen
TN7063
Synonym: NSC 403155,N-Acetyldemecolcine,N-Methylcolchicine,N-Acetylcolchamine
Target: Others
Tubulin polymerization-IN-43
T77647
Synonym:
Target: Apoptosis, Microtubule Associated
YS-370
T60009
Synonym:
Target: P-gp
Tubulin inhibitor 11
T67935
Synonym:
Target: Apoptosis, Microtubule Associated
LP-261
T9595
Synonym:
Target: Microtubule Associated
Suprafenacine
T28886
Synonym: N'-[(E)-(4-methylphenyl)methylidene]-4,5,6,7-tetrahydro-1H-indazole-3-carbohydrazide
Target: Microtubule Associated
Tartaric acid disodium dihydrate
T65128
Synonym: Disodium L-(+)-Tartrate Dihydrate
Target: Phosphatase, Endogenous Metabolite
Plinabulin
T2511
Synonym: NPI-2358
Target: Microtubule Associated
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TargetMol