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Search Results for " cleaved-parp "

5

Compounds

Cat No. Product Name Synonyms Targets
T15212 Emamectin Benzoate MK-244 Apoptosis , Reactive Oxygen Species , GABA Receptor , Parasite
Emamectin Benzoate (MK-244), by binding gamma-aminobutyric acid (GABA) receptor and glutamate-gated chloride channels disrupting nerve signals within arthropods, acts as a chloride channel activator.
T10896L CSRM617 hydrochloride CSRM617 hydrochloride(787504-88-5 Free base) Apoptosis , Others , Androgen Receptor
CSRM617 hydrochloride is a selective small-molecule inhibitor of the transcription factor ONECUT2 ( OC2, a master regulator of androgen receptor) with a K d of 7.43 uM in SPR assays, directly binds to OC2-HOX domain. CSR...
T62044 Anticancer agent 71
Anticancer agent 71 (Compound 4b) is a potent anticancer agent. Anticancer agent 71 arrests cell cycle at G2/M phase. Anticancer agent 71 induces apoptosis through upregulating Bax, Ikb-α and cleaved PARP and downregulat...
T79482 Anticancer agent 137 PI3K
Anticancer agent 137 (8q), a potent PI3k inhibitor, exhibits broad-spectrum anticancer activity by inducing G2/M cell cycle arrest and apoptosis. It increases levels of cleaved PARP, and caspases 3 and 7, making it usefu...
T78054 JNJ-1013 Apoptosis
JNJ-1013 is a potent and selective IRAK1 degrader, demonstrating IC50 values of 72 nM for IRAK1, 443 nM for IRAK4, and 1071 nM for VHL FP. It induces apoptosis and augments the expression of cleaved PARP while decreasing...
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