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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T9063 | Clathrin-IN-1 | HIV Protease | |
Clathrin-IN-1 is a inhibitor of clathrin, and inhibits clathrin-mediated endocytosis (CME) by associating with the terminal domain of clathrin. It has the potential for anti-cancer research. | |||
T25257 | Clathrin-IN-25 | Clathrin IN 25 | |
Clathrin-IN-25 is the most effective clathrin terminal domain-amphiphysin inhibitor reported to date. | |||
T72894 | Clathrin-IN-2 | ||
Clathrin-IN-2 is a potent inhibitor of clathrin-mediated endocytosis (CME), demonstrating an IC50 value of 2.3 μM. Additionally, it exhibits inhibitory effects on dynamin I GTPase, with an IC50 of 7.7 μM. | |||
T25256 | Pitstop1 | Clathrin inhibitor 1,Clathrin-inhibitor-1,Clathrin IN 1 | |
Clathrin-IN-1 is a selective clathrin inhibitor that acts by addressing clathrin function in cell physiology with potential applications as an inhibitor of virus and pathogen entry and as a modulator of cell signaling. | |||
T26357 | Pitstop 2 | Apoptosis | |
Pitstop2 is a selective inhibitor of amphiphysin association of clathrin terminal domain with an IC50 value of 12 μM. Pitstop2 acutely interferes with receptor-mediated endocytosis, entry of HIV, and synaptic vesicle rec... | |||
T6822 | Hydroxy-Dynasore | Dyngo-4a | Dynamin |
Hydroxy-Dynasore (Dyngo-4a) , a effective dynamin inhibitor, inhibits withDynI (brain), DynI (rec), and DynII (rec) of IC50 of 0.38 μM, 1.1 μM, and 2.3 μM, respectively. | |||
T64369 | Dynamin IN-2 | Dynamin | |
Dynamin IN-2 (compound 43) is a Wiskostatin analogue. Dynamin IN-2 is a potent dynamin inhibitor (dynamin I GTPase, IC50= 1.0 μM). Dynamin IN-2 blocks clathrin mediated endocytosis (CME) (IC50= 9.5 μM). | |||
T64368 | ES9-17 | Others | |
ES9-17, an analog of ES9 (endosidin9), is an inhibitor of clathrin-mediated endocytosis (CME). ES9-17 inhibits the uptake of FM4-64 and transferrin. ES9-17 inhibits root growth of Arabidopsis seedings. | |||
T15556 | Ikarugamycin | Others | |
Ikarugamycin, an antibiotic, is an inhibitor of clathrin-mediated endocytosis (CME). | |||
T39050 | Pitnot-2 | ||
Pitnot-2 is an inert analogue of the clathrin inhibitor Pitstop 2, commonly employed as a negative control in experimental studies. | |||
T61488 | Dynole 2-24 | ||
Dynole 2 24 is an indole-based dynamin GTPase inhibitor ( IC 50 =0.56 μM for dynamin I). Dynole 2 24 is nontoxic and shows increased potency against dynamin I and II in vitro and in cells (IC (CME) =1.9 μM). Dynole 2 2... | |||
T83891 | Sulfonadyn-47 | ||
Sulfonadyn-47 is a dynamin inhibitor that effectively inhibits dynamin GTPase activity with an IC50 of 3.5 µM in cell-free assays. Additionally, it disrupts clathrin-mediated endocytosis in U2OS cells (IC50 = 27.3 µM) an... | |||
T36368 | 2H-Cho-Arg (trifluoroacetate salt) | ||
2H-Cho-Arg is a steroid-based cationic lipid that contains a 2H-cholesterol skeleton coupled to an L-arginine head group and can be used to facilitate gene transfection. It forms a complex with plasmid DNA (pDNA) and dec... |