cccdna — TargetMol Chemicals

Search Result

Search Results for " cccdna "

Compounds

Cat No.	Product Name	Synonyms	Targets
T22142	RO8191	RO4948191,CDM-3008	HCV Protease , HBV , JAK , IFNAR , STAT
	RO8191 (CDM-3008) (CDM-3008) is an agonist of interferon (IFN) receptor.		HCV Protease , HBV , JAK , IFNAR , STAT
T11409	GLP-26		HBV
	GLP-26 disrupts the encapsidation of pre-genomic RNA, causes nucleocapsid disassembly and reduces cccDNA pools. GLP-26 is a HBV capsid assembly modulators (CAM), inhibits HBV DNA replication in Hep AD38 system (IC50=3 nM...		HBV
T73440	Ccc_R08		HBV
	ccc_R08 is an orally available HBV cccDNA inhibitor that reduces extracellular levels of HBV DNA, HBsAg, and HBeAg in a dose-dependent manner. ccc_R08 is investigational for use in the treatment of HBV infections. ccc_R0...		HBV
T6446	Clevudine	L-FMAU,Levovir	HBV , DNA/RNA Synthesis
	Clevudine (Levovir) is a synthetic pyrimidine analogue with activity against hepatitis B virus (HBV). Intracellularly, clevudine is phosphorylated to its active metabolites, clevudine monophosphate and triphosphate. The ...		HBV , DNA/RNA Synthesis
T26771	Bentysrepinine	Y 101,Y101,Y-101
	Bentysrepinine, a novel anti-HBV agent, inhibits DNA-HBV and cccDNA activities for the treatment of hepatitis B virus (HBV)-infected hepatitis.
T61886	HBV-IN-16
	HBV-IN-16 is a quinoline derivative, which has an effective inhibitory effect on covalent closed circular DNA (cccDNA). CccDNA is the template for viral RNA transcription and subsequent viral DNA generation. HBV-IN-16 ha...
T73006	Cis-ccc_R08
	cis-ccc_R08 infection . cis-ccc_R08 is a cccDNA (covalently closed circular DNA) inhibitor .
T73283	HBV-IN-32
	HBV-IN-32, a potent inhibitor of covalently closed circular DNA (cccDNA), exhibits significant anti-Hepatitis B Virus (HBV) activity by achieving an IC50 of 0.14 µM against HBsAg. Additionally, it impedes cell growth.
T73282	HBV-IN-31
	HBV-IN-31, a potent inhibitor of covalently closed circular DNA (cccDNA), demonstrates significant anti-HBV activity by inhibiting cell growth and exhibiting an IC50 value of 0.13 µM for HBsAg.
T72884	Trans-ccc_R08
	Trans-ccc_R08 is a potent inhibitor of cccDNA (covalently closed circular DNA), displaying significant activity in decreasing HBeAg levels with an IC50 value of 0.08 µM. This compound shows promise for research into the ...
T62355	HBV-IN-14
	HBV-IN-14 is a pyridinopyrimidinone compound and a potent covalent closed-loop DNA (cccDNA) inhibitor. HBV-IN-14 has potential for the study of HBV infection.
T72796	Junceellolide C
	Junceellolide C, a potent anti-HBV agent, acts as a transcription inhibitor of cccDNA, effectively inhibiting HBV DNA replication and significantly reducing supernatant HBV RNA levels in HepAD38 cells, with EC50 values o...
T73281	HBV-IN-30
	HBV-IN-30 (ex44), a flavone derivative, acts as a potent inhibitor of covalently closed circular DNA (cccDNA), which is essential for viral RNA transcription and subsequent viral DNA production. This compound shows promi...
T73249	HBV-IN-15
	HBV-IN-15, a flavone derivative, acts as a potent inhibitor of covalently closed circular DNA (cccDNA), which is crucial for viral RNA transcription and subsequent viral DNA production. This compound shows promise for re...
T73280	HBV-IN-29
	HBV-IN-29 (ex8), a flavone derivative, functions as a potent inhibitor of covalently closed circular DNA (cccDNA), which is essential for viral RNA transcription and subsequent viral DNA replication. This compound shows ...
T61115	HBV-IN-25
	HBV-IN-25 is a novel chemical compound that acts as a potent HBV cccDNA reducer when administered orally. It exhibits significant anti-HBeAg potency and anti-HBV activity, with IC50 values of 0.58 μM and 1.15 μM, respect...