biliary — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T3978	Linerixibat	GSK2330672,Iinerixibat	HBV
	Linerixibat (GSK2330672) is a highly effective, nonabsorbable ASBT inhibitor (IC50: 42 ± 3 nM). It can lower glucose in an animal model of type 2 diabetes and shows excellent developability properties.		HBV
T0396	Pipemidic acid	Acido pipemidico	Antibacterial , Antibiotic
	Pipemidic acid (Acido pipemidico), a new antibacterial agent, inhibits the activity of Pseudomonas aeruginosa.		Antibacterial , Antibiotic
T13522	7-Ketolithocholic acid	3α-Hydroxy-7-oxo-5β-cholanic acid	Endogenous Metabolite
	7-Ketolithocholic acid (3α-Hydroxy-7-oxo-5β-cholanic acid) (3α-Hydroxy-7-oxo-5β-cholanic acid) is capable of absorption and serves to suppress the production of endogenous bile acid and the secretion of biliary cholester...		Endogenous Metabolite
T19239	Cicloxilic acid	Cycloxilic acid	Others
	Cicloxilic acid（Cycloxilic acid） has choleretic activity and inhibits biliary cholesterol output.		Others
TJA2398	Taurodeoxycholic acid sodium hydrate	Sodium taurodeoxycholate monohydrate,Taurodeoxychloic Acid sodium hydrate,Taurohyodeoxycholic acid sodium salt	Apoptosis , Caspase
	Taurodeoxycholic acid sodium hydrate (Sodium taurodeoxycholate monohydrate), a hydrophilic bile salt, on bile salt and biliary lipid secretion in the rat.		Apoptosis , Caspase
T2532	Tauroursodeoxycholate	Taurolite,Tauroursodeoxycholic Acid,UR 906,Ursodeoxycholyltaurine,TUDCA	Apoptosis , ERK , P450 , Caspase , Endogenous Metabolite
	Tauroursodeoxycholate (UR 906), also known as ursodoxicoltaurine, is a highly hydrophilic tertiary bile acid that is produced in humans at a low concentration. Tauroursodeoxycholate is the more hydrophilic form of ursode...		Apoptosis , ERK , P450 , Caspase , Endogenous Metabolite
T23923	Cyclobutyrol	BRN 2209058,BRN-2209058,BRN2209058,Cyclobutyrolum,JL 130
	Cyclobutyrol is a choleretic agent. It also inhibits biliary lipid secretion.
T30904	Cholecystokinin-J	CCK-J
	Cholecystokinin-J can be used in cholecystography, radiomanometry and biliary cinematography.
T31820	Fluorescein lisicol	NRL972,NRL-972,NRL 972
	Fluorescein lisicol, as an investigational marker of hepatic biliary transporter function, is a fluorescent-labeled bile salt.
T26943	CAP-7.1	CAP7.1
	CAP-7.1, a DNA topoisomerase inhibitor, is used potentially for the treatment of biliary cancer and non-small cell lung cancer.
T32179	Ioglycamic acid	BE-419,Ioglycamide,BE419,BE 419
	Iodoxylic acid, a mixture of meglumine and sodium salts, is used to visualize the biliary tract as a radiopaque diagnostic aid.
T32180	Iophendylate	Maiodil,Panthopaque,Iodophendylate,Ethiodan,Ioglunide
	Iofendylate is a molecule used as a contrast medium. It is an absorbable iodized fatty acid of low viscosity used for roentgenography of the spinal cord, biliary tree, sinuses, and body cavities.
T71403	Cyclobutyrol sodium salt
	Cyclobutyrol sodium salt is a choleretic agent which also inhibits biliary lipid secretion.
T33314	Methantheline Bromide	Frenogastrico,Dixamone bromide,Banthine,Asabaine,Methanthelinium bromide
	Methantheline Bromide is a synthetic spasmolytic used to relieve cramps or spasms of the stomach, bowel, and bladder. It is also useful for intestinal or gastric ulcers (peptic ulcer disease), intestinal problems, pancre...
T27167	Diclofenac Acyl Glucuronide
	Diclofenac Acyl Glucuronide is a major biliary metabolite of Diclofenac (GLXC-07892), a nonsteroidal antiinflammatory drug and COX inhibitor.
T6582L	Mezlocillin	Bay-f 1353,Meslocillin,Melocin,Baypen,Mezlin
	Meloxicillin is a broad-spectrum penicillin antibiotic that is active against both Gram-negative bacteria and some Gram-positive bacteria. Unlike most other broad-spectrum penicillin, it is excreted by the liver and can ...
T30451	Biliatresone
	Biliatresone is a very rare natural isoflavone-related 1, 2-diaryl-2-allenone found in Dysphania Glomulifera and D. littoralis. It has been found to cause extrahepatic biliary atresia in zebra fish models.
T25325	Dicyclonon	LAB 145-138H,BAS 145-138
	Dicyclonon is a muscarinic antagonist utilized as an antispasmodic and in urinary incontinence. It has little effect on glandular secretion or the cardiovascular system. It has some local anesthetic properties and is uti...
T7475	S-Adenosyl-L-methionine	AdoMet,Ademetionine,SAMe,S-Adenosyl methionine	Others , Endogenous Metabolite
	S-Adenosyl-L-methionine (Ademetionine) is an intermediate metabolite of methionine,for treatment of primary biliary cirrhosis and major depressive disorder.		Others , Endogenous Metabolite
T63793	Tauro-ω-muricholic acid sodium
	Tauro-ω-muricholic acid sodium (TωMCA sodium) is an analogue of tauro-α-muricholic acid, a bile acid of hepatic origin. Tauro-ω-muricholic acid sodium can be used as a serum marker for early onset neonatal sepsis (EOS) a...