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Search Result

Search Results for " bifunctional "

20

Compounds

Cat No. Product Name Synonyms Targets
T39710 ARV-471 Vepdegestrant Estrogen Receptor/ERR
ARV-471 (Vepdegestrant) is a orally active Cereblon -based estrogen receptor (ER) PROTAC degrader. ARV-471 is developed for the research of breast cancer.
T6798 Tretazicar 5-Aziridino-2,4-dinitrobenzamide,CB1954,NSC 115829 DNA Alkylator/Crosslinker , DNA Alkylation
CB1954(Tretazicar (NSC-115829)), an anticancer prodrug, is activated by NAD(P)H quinone oxidoreductase 2. It is converted in the presence of the enzyme NQO2 and co-substrate caricotamide ( EP-0152R) (EP) into a potent cy...
T7750 N-[3,5-bis(trifluoroMethyl)phenyl]-N'-[(9R)-6'-Methoxycinchonan-9-yl]- Thiourea Others
N-[3,5-bis(trifluoroMethyl)phenyl]-N'-[(9R)-6'-Methoxycinchonan-9-yl]- Thiourea is a cinchona alkaloid-derived bifunctional catalyst.
T17159 Treosulfan NSC 39069,Treosulphan DNA Alkylator/Crosslinker , DNA Alkylation
Treosulfan (Treosulphan) is a bifunctional alkylating agent. It also has activity in ovarian cancer and other solid tumor types.
T11938L Macropa-NH2 Others
Macropa-NH2 is a bifunctional analog of macropa, a carrier molecule that is often coupled to antibodies and is often used as a chelator in cancer research.
T15178 DTRIM24 Others
dTRIM24 is a selective bifunctional TRIM24 degradation agent based on PROTAC technology, consisting of the ligands von Hippel-Lindau and TRIM24.
T82236 HBED-CC-tris(tert-butyl ester)
HBED-CC-tris(tert-butyl ester), a derivative of HBED-CC, serves as a bifunctional chelating agent with applications in agricultural research and radiopharmacy [1].
T18728 Sulfo-SMCC sodium Others
Sulfo-SMCC sodium, a widely utilized non-cleavable, hetero-bifunctional crosslinker for antibody-drug conjugates (ADCs), features both N-hydroxysuccinimide (NHS) ester and maleimide groups. These functionalities enable i...
T4382 Proguanil hydrochloride Paludrine hydrochloride,Chlorguanide hydrochloride,Chloroquanil Others , Dehydrogenase , DNA/RNA Synthesis , Antifolate , Parasite
Proguanil hydrochloride (Chloroquanil) is a biguanide compound which metabolizes in the body to form cycloguanil, an anti-malaria agent.Upon hydrolysis, Proguanil hydrochloride is converted to its active cyclic triazine ...
T28846 SR16835 AT-202,AT202,SR 16835,SR-16835
SR16835 is a NOP receptor agonist, with low-affinity bifunctional activity at the μ opioid receptor.
T25140 BCH 2763 BCH2763,BCH-2763
BCH 2763 is an effective, selective bifunctional thrombin inhibitor that blocks both the anion binding exosite and the active catalytic site.
T19168 9-Azido-Neu5DAz Others
9-Azido-Neu5DAz is a non-natural bifunctional carbohydrates as imaging agent.
T26803 Bibw 22 Bibw22,Bibw-22
Bibw 22 is a bifunctional modulator of P-glycoprotein and nucleoside transport.
T17469 Azide-PEG3-Sulfone-PEG3-azide Others
Azide-PEG3-Sulfone-PEG3-azide is a polyethylene glycol (PEG)-based bifunctional molecule, specifically designed as a PROTAC linker for the synthesis of PROTACs[1].
T14163 Ald-Ph-amido-C2-PEG3-NH-Boc Others
Ald-Ph-amido-C2-PEG3-NH-Boc is a polyethylene glycol (PEG)-based bifunctional linker utilized for the synthesis of Proteolysis Targeting Chimeras (PROTACs)[1].
T14267 Aminooxy-PEG3-C2-NH-Boc Others
Aminooxy-PEG3-C2-NH-Boc is a PEGylated PROTAC linker utilized in the synthesis of PROTACs, an emerging class of bifunctional molecules for targeted protein degradation[1].
T19207 BFCAs-1 Others
BFCAs-1 is a polyamine polycarboxylic bifunctional chelating agent (BFCAs) with a broad range of applications in biology, chemistry, medicine and diagnostic imaging.
T18834 Thiol-PEG-CH2COOH (MW 5000) Others
Thiol-PEG-CH2COOH (MW 5000) is a Polyethylene glycol (PEG) derived link molecule, commonly utilized in the construction of PROTACs, which are bifunctional compounds designed for targeted protein degradation [1].
T16181 N-(Azido-PEG2)-N-Boc-PEG4-Boc Others
N-(Azido-PEG2)-N-Boc-PEG4-Boc is a PEG-based bifunctional linker employed for the synthesis of PROTACs.
T68272 Batefenterol Succinate
Batefenterol Succinate is a first-in-class inhaled bifunctional bronchodilator possessing muscarinic receptor antagonist and β2-adrenoceptor agonist properties.
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